Metabolite: h2o_c


Descriptive name:

H2O H2O

Model:

Recon3D

Formula:

H2O

Charge:

0

Compartment:

c - cytosol

Reactions:

BiGG ID
Name
BPNT2
3'-Phospho-5'-adenylyl sulfate 3'-phosphohydrolase
DODECANACt
Transport of Dodecanedioic Acid by FATP
ASNCYSCYSr
Metabolism (Formation/Degradation) of AsnCysCys
PHELEUr
Metabolism (Formation/Degradation) of PheLeu
RE3436C
Leukotriene-B4 20-Monooxygenase
HMR_0431
HMR 0431
GCHOLAt3
ABC bile acid transporter
THRHISHISr
Metabolism (Formation/Degradation) of ThrHisHis
TRYPTAOX
Tryptamine:oxygen oxidoreductase(deaminating)(flavin-containing)
NTD9
5'-nucleotidase (GMP)
13DAMPPOX
1,3-Diaminopropane:oxygen oxidoreductase (deaminating)
H2Otp
H2O transport peroxisomal
6MELACAChep
Conversion of lactone form of 6-exomethylene-lovastatin to acid form
TRPGLYPHEr
Metabolism (Formation/Degradation) of TrpGlyPhe
GLXO1
Glyoxylate oxidase
PE15_HSABCt
Transport of 1-Pentadecanoylglycerophosphoethanolamine (C15:0 Pe)
ADA
Adenosine deaminase
HMR_0819
Beta-Galactosidase
CE4843HYDc
Acylcoa Hydrolase, Cis, Cis-11, 14-Eicosadienoyl Coenzyme A
6BHGLZABCt
Excretion of 6-beta-OH-gliclazide into bile
CDCA3Gte
Glucuronidated bile acid excretion (CDCA-3G)
RADH
Retinal dehydrogenase
HMR_5387
5- (Methylthio)-2, 3-Dioxopentyl-Phosphate Phosphohydrolase (Isomerizing)
ASPGLUPROr
Metabolism (Formation/Degradation) of AspGluPro
DOPAOQNOX
Dopamine-O-Quinone Oxidase
NDP6
Nucleoside-diphosphatase (dCDP)
H2Otn
H2O transport nuclear
HMR_1756
Cholate Coenzyme A Ligase
ACMPGLUTthc
Uptake of acetaminophen-glutathione-conjugate by the hepatocytes
PI35P3P
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase
PCt
Phosphatidylcholine transporter
RE1099C
Steryl-Sulfatase
RAHY
Retinoic acid hydroxylation (P450)
PCHOLN19_HSABCt
Transport of 1-NoNADecanoylglycerophosphocholine, Sn1-Lpc (19:0)
HMR_2581
Prostaglandin-Endoperoxide Synthase
HKYNH
3 Hydroxy L kynurenine hydrolase
NTD3
5'-nucleotidase (dCMP)
TETDECA511ACc
Hydrolysis of Tetradecadienoyl Coenzyme A to Cis-5, 8-Tetradecadienoic Acid
APRGSTRNABCt
Hydroxyprogesterone Transport, Active
ASNPHEASPr
Metabolism (Formation/Degradation) of AsnPheAsp
PHETRPLEUr
Metabolism (Formation/Degradation) of PheTrpLeu
HISLYSTHRr
Metabolism (Formation/Degradation) of HisLysThr
ACMPGLUthc
Uptake of acetaminophen-glucuronide-conjugate by the hepatocytes
PCHOLN226_HSPLA2
Formation of 1-Docosahexenoylglycerophosphocholine (Delta 4, 7, 10, 13, 16, 19), Sn1-Lpc (22:6) by Phospholipase A2
PCHOL2LINL_HSABCt
Transport of 2-Linoleoylglycerophosphocholine
HMR_6747
L-Metanephrine:Oxygen Oxidoreductase (Deaminating) (Flavin-Containing)
r1518
ATP-binding Cassette (ABC) TCDB:3.A.1.211.1
TRPPROVALr
Metabolism (Formation/Degradation) of TrpProVal
TRPGLUTYRr
Metabolism (Formation/Degradation) of TrpGlutyr
GLUTHRLYSr
Metabolism (Formation/Degradation) of GluThrLys
CRVSM24teb
Efflux of cerivastatin-M24 into bile
CRVSATPthc
Cerivastatin uptake by hepatocytes by active transport
DHPM2
Dihydropyrimidinase (dihydrothymine)
DCTPD
DCTP deaminase
ALAASNLEUr
Metabolism (Formation/Degradation) of AlaAsnLeu
HMR_6978
Signal Peptidase I
XAO2
Xanthine oxidase (hypoxanthine)
STS2
Steryl-sulfatase
PRGNLONESte
Transport of Pregnenolone Sulfate, Extracellular
SERGLYGLUr
Metabolism (Formation/Degradation) of SerGlyGlu
RETH
Retinyl ester hydrolase
RNTR2
Ribonucleoside triphosphate reductase GTP
HMR_0291
HMR 0291
FAH1
Fatty acid omega-hydroxylase
HMR_1538
Sterol 14Alpha-Demethylase
3DHCHOLabc
3-Dehydrocholic acid ABC bile acid transporter
CYSAMPtev
Efflux of cysteine-conjugate-acetaminophen into hepatic vein
TRPVALASPr
Metabolism (Formation/Degradation) of TrpValAsp
RE3218C
Steryl-Sulfatase
PGLYCABCte
Phosphatidylglycerol Transport by ABCa3
HISMETGLNr
Metabolism (Formation/Degradation) of HisMetGln
HMR_8572
Alpha-Amylase
P4502F1
Cytochrome P450 2F1
PHEPROARGr
Metabolism (Formation/Degradation) of PheProArg
PHESERTRPr
Metabolism (Formation/Degradation) of PheSerTrp
XAO
Xanthine oxidase
HMR_0311
HMR 0311
PHETHPTOX
L-Phenylalanine,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating) Phenylalanine, tyrosine and tryptophan biosynthesis EC:1.14.16.1
VALHISASNr
Metabolism (Formation/Degradation) of ValHisAsn
HMR_1988
Steroid 21-Monooxygenase
CYSSERMETr
Metabolism (Formation/Degradation) of CysSerMet
TMABADH
4-trimethylaminobutyraldehyde dehydrogenase
THYPX
Thyroid peroxidase
ALAARGCYSr
Metabolism (Formation/Degradation) of AlaArgCys
ATPasel_1
V-Type ATPase, H+ Transporting, Lysosomal
FAEL184
Fatty-acyl-CoA elongation (n-C20:4CoA)
THCHOLSTOICATP
Transport of 3Alpha, 7Alpha, 12Alpha-Trihydroxy-5Beta-Cholestanoate, Active Transport
HMR_0391
HMR 0391
BPNT
3',5'-bisphosphate nucleotidase
6HMSMVACIDhep
Conversion of 6-beta-hydroxy-methyl simvastatin lactone to acid form
RE3286C
Unspecific Monooxygenase
AHANDROSTANte
Transport of 3Alpha-Hydroxy-5Beta-Androstan-17-One, Extracellular
RE3570C
RE3570
PCHOLLINL_HSABCt
Transport of 1-Linoleoylglycerophosphocholine (Delta 9, 12)
HMR_0277
HMR 0277
25HVITD3c
1-alpha hydroxylation of 25-hydroxy vitamin D
CE2513ATP
Transport of 15-Tetracosenoate, Active Transport
PAFH
Platelet-activating factor acetylhydrolase
HMR_6545
HMR 6545
GLZABCteb
Excretion of gliclazide into bile
DCA3Gte
Glucuronidated bile acid excretion (DCA-3G)
DASCBH
L-Dehydroascorbate lactonohydrolase
HMR_1981
Steroid 17Alpha-Monooxygenase
2HATVACIDteb
Efflux of 2-hydroxy-atorvastatin-acid into bile
CE5025t
Transport of 5-S-Glutathionyl-Dopamine
r0186
Ethanolamine-phosphate phospho-lyase (deaminating) EC:4.2.3.2
ARGGLYGLYr
Metabolism (Formation/Degradation) of ArgGlyGly
LIPOti_1
Transport of Lipoate via Sodium Symport
GLNTYRLEUr
Metabolism (Formation/Degradation) of GlntyrLeu
RE3122C
RE3122
VALTRPVALr
Metabolism (Formation/Degradation) of ValTrpVal
ACNAMPH
N-Acetylneuraminate 9-phosphate phosphohydrolase
DESAT20_2
Fatty acyl-CoA desaturase (n-C20:4CoA -> n-C20:5CoA)
AGDC
N-acetylglucosamine-6-phosphate deacetylase
LTC4CP
Leukotriene C4 carboxypeptidase
DOPACHRMISO
L-dopachrome isomerase 1
DESFVSteb
Efflux of N-desisopropyl-fluvastatin into bile for excretion into faeces
3M4HDXPAC
3-Methoxy-4-hydroxyphenylacetaldehyde:NAD+ oxidoreductase
HMR_6583
Phosphatidylinositol-3, 4, 5-Trisphosphate 3-Phosphatase
HMR_0358
Palmitoyl Coenzyme A Hydrolase
PHEGLNPHEr
Metabolism (Formation/Degradation) of PheGlnPhe
NTD10
5'-nucleotidase (XMP)
RNTR4
Ribonucleoside triphosphate reductase UTP
ARGALAALAr
Metabolism (Formation/Degradation) of ArgAlaAla
ETOHMO
Ethanol monooxygenase
CHOLATEt3
ABC bile acid transporter
HMR_1681
Cholestanetriol 26-Monooxygenase
S3MEACMPtev
Efflux of sulphate-conjugate-3-methoxy-acetaminophen into hepatic vein
RE1803C
RE1803
SPHMYLN181181_hs_ATPt
Transport of Sphingomyelin (D18:1/18:1), Active
PHETYRGLNr
Metabolism (Formation/Degradation) of PhetyrGln
BETALDHy
Betaine-aldehyde dehydrogenase
HMR_4816
2-Amino-4-Hydroxy-6- (Erythro-1, 2, 3-Trihydroxypropyl) Dihydropteridine Triphosphate Phosphohydrolase (Alkaline Optimum)
PCHOLOLE_HSABCt
Transport of 1-Oleoylglycerophosphocholine (Delta 9)
PHEPHEr
Metabolism (Formation/Degradation) of PhePhe
HMR_0422
Palmitoyl Coenzyme A Hydrolase
PCHOLPALM_HSPLA2
Formation of 1-Palmitoylglycerophosphocholine by Phospholipase A2
HMR_0362
Palmitoyl Coenzyme A Hydrolase
GLYGLYCNc
Hydrolysis of glycylycine for uptake
ARGSERSERr
Metabolism (Formation/Degradation) of ArgSerSer
7DHCDCHOLabc
7-Dehydrochenodeoxycholic acid ABC bile acid transporter
TYRARGGLUr
Metabolism (Formation/Degradation) of TyrArgGlu
HC02195te
Transport of Bile Acid, Tauroursodeoxycholate, Active Transport
HISARGCYSr
Metabolism (Formation/Degradation) of HisArgCys
PROLEUARGr
Metabolism (Formation/Degradation) of ProLeuArg
KDNH
2-keto-3deoxy-D-glycero-D-galactononic acid phosphohydrolase
ARGPHEARGr
Metabolism (Formation/Degradation) of ArgPheArg
DOPAc
Formation of Dopamine
UDPRIBc
UDPRIBc
RE2563C
RE2563
ILEPROLYSr
Metabolism (Formation/Degradation) of IleProLys
ADRNLPVESSEC_1
Adrenaline Secretion via Secretory Vesicle (ATP Driven)
FAEL183
Fatty-acyl-CoA elongation (n-C18:3CoA)
HMR_2295
Stearoyl Coenzyme A 9-Desaturase
GLYOX
Hydroxyacylglutathione hydrolase
P4502A6
Cytochrome P450 2A6
3ISPVSteb
Efflux of 3-alpha-iso-pravastatin into bile
ALOX52
Arachidonate 5-lipoxygenase
HMR_1503
Methylsterol Monooxygenase
HMR_0234
Palmitoyl Coenzyme A Hydrolase
FAS80COA_L
Fatty acyl CoA synthase n C80CoA lumped reaction
r1527
ATP-binding Cassette (ABC) TCDB:3.A.1.211.1
PI345P5P
Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase
FPGS7_1
Folylpolyglutamate Synthetase (10Fthf)
TYRPHETYRr
Metabolism (Formation/Degradation) of TyrPhetyr
SMO
Squalene monooxygenase
PCHOLN281_HSPLA2
Formation of Lysopc A C28:1 (Delta 5) by Phospholipase A2
HMR_0268
Palmitoyl Coenzyme A Hydrolase
HMR_8578
Alpha-Amylase
GLYLYSCYSr
Metabolism (Formation/Degradation) of GlyLysCys
AND19ONEc
Hydroxylation of Androst-4-Ene-3, 17-Dione
LNS14DM
Cytochrome P450 lanosterol 14 alpha demethylase NADP
MCITS
2-methylcitrate synthase
2HATVACIDhc
Conversion of 2-hydroxy-atorvastatin-lactone to its acid form in hepatocytes
3HPVSTETteb
Efflux of 3-S-hydroxy-pravastatin-tetranor into bile
LTD4DP
Leukotriene D4 dipeptidase
NADPPPS
NADP phosphatase
r1522
ATP-binding Cassette (ABC) TCDB:3.A.1.211.1
LYSCYSHISr
Metabolism (Formation/Degradation) of LysCysHis
PCHOL2PALM_HSPLA2
Formation of 2-Palmitoylglycerophosphocholine by Phospholipase A2
HMR_0767
Phosphatidate Phosphatase
ACMPtu
Efflux of acetaminophen by P-gp from the enterocytes into lumen
HMR_0950
HMR 0950
RNDR4
Ribonucleoside-diphosphate reductase (UDP)
CE2537ATP
Transport of 15-Hydroxy- (8Z, 11Z, 13E)-Eicosatrienoate, Active Transport
MDRPD
5-Methylthio-5-deoxy-D-ribulose 1-phosphate dehydratase
MERACMPthc
Uptake of acetaminophen-mercapturate-conjugate by the hepatocytes
NDERSVteb
Efflux of N-desmethyl-rosuvastatin into bile
VALARGGLYr
Metabolism (Formation/Degradation) of ValArgGly
HMR_0276
Palmitoyl Coenzyme A Hydrolase
SPHMYLN18120_hs_ATPt
Transport of Sphingomyelin (D18:1/20:0), Active
SPHMYLN18116_hs_ATPt
Transport of Sphingomyelin (D18:1/16:0), Active Transport
HMR_2472
HMR 2472
THFt2_1
Tetrahydrofolate Transport via Anion Antiport
LVSTACIDtu
Efflux of lovastatin acid by P-gp from the enterocytes into lumen
CYSLEUTHRr
Metabolism (Formation/Degradation) of CysLeuThr
FEROc
Ferroxidase
HMR_0261
HMR 0261
r0381
Hypotaurine:NAD+ oxidoreductase Taurine and hypotaurine metabolism EC:1.8.1.3
CYTD
Cytidine deaminase
HMR_0419
HMR 0419
ESTRSABCtc
Estrone-Sulphate Transport by ABCa8
HMR_0206
Palmitoyl Coenzyme A Hydrolase
PHEASNMETr
Metabolism (Formation/Degradation) of PheAsnMet
PI3PP
Phosphatidylinositol-3-phosphate 3-phosphatase
LPS
Lipase
LEUGLYHYc
Hydrolysis of leucylglycine
TRPGLYLEUr
Metabolism (Formation/Degradation) of TrpGlyLeu
GLUN
Glutaminase
ASNTYRPHEr
Metabolism (Formation/Degradation) of AsntyrPhe
RNDR3
Ribonucleoside-diphosphate reductase (CDP)
PE226_HSABCt
Transport of 1-Docosahexenoylglyceroethanolamine (Delta 4, 7, 10, 13, 16, 19), Lpe (22:6)
THMP
Thiamin phosphatase
HMR_0601
Phosphatidate Phosphatase
SPHMYLN181201_hs_ATPt
Transport of Sphingomyelin (D18:1/20:1), Active
CE2209te
Transport of 5Alpha-Androstane-3Alpha, 17Beta-Diol, Extracellular
UDPGP
UDP-glucose glucophosphohydrolase
HXAND
Hypoxanthine dehydrogenase
CYSASNMETr
Metabolism (Formation/Degradation) of CysAsnMet
LPS2
Lipase
AMPTASEPG
Aminopeptidase (pro-gly)
3MOXTYROX
3-Methoxytyramine:oxygen oxidoreductase (deaminating)
HCA24Gte
Glucuronidated bile acid excretion (HCA-24G)
HMBS
Hydroxymethylbilane synthase
ACLYSHYc
Hydrolysis of Acetyl-Lysine
IMPC
IMP cyclohydrolase
HMR_1990
21-Deoxycortisol, Hydrogen-Donor:Oxygen Oxidoreductase (21-Hydroxylating)
ARGCYSSERr
Metabolism (Formation/Degradation) of ArgCysSer
RE1918C
RE1918
DEDOLP2_L
Dehydrodolichol phosphate phosphatase (liver)
HMR_1940
Pregnenolone, Hydrogen-Donor:Oxygen Oxidoreductase (21-Hydroxylating)
HMR_0242
Palmitoyl Coenzyme A Hydrolase
2AMACHYD
2-Aminoacrylate hydrolysis
HCA6Gte
Glucuronidated bile acid excretion (HCA-6G)
HMR_1037
Arachidonate 12-Lipoxygenase
RE0958C
Alpha-Amylase
LCADi_D
Lactaldehyde dehydrogenase
PCHOLET_HSABCt
Transport of 1-Eicosatrienoylglycerophosphocholine (Delta 11, 14, 17)
r2505
ATP-binding Cassette (ABC) TCDB:3.A.1.208.8
r1523
ATP-binding Cassette (ABC) TCDB:3.A.1.211.1
PSFLIP
Phosphatidylserine flippase
CE1273t1
Transport of 5Beta-Cholestane-3Alpha, 7Alpha, 12Alpha, 24S, 25-Pentol, Active Transport
r0642
(S)-Methylmalonate semialdehyde:NAD+ oxidoreductase Valine, leucine and isoleucine degradation EC:1.2.1.3
ASPGLUTRPr
Metabolism (Formation/Degradation) of AspGluTrp
APRTO2
N acetylputrescine oxygen oxireductase deaminating
5HPETATP
Transport of 5(S)-HPETE, Active Transport
ATVLACtu
Efflux of atorvastatin lactone by P-gp from the enterocytes into lumen
MACOXO
3-Methylimidazole acetaldehyde:NAD+ oxidoreductase
PCHOLN203_HSPLA2
Formation of 1-Dihomo-Linolenoylglycerophosphocholine (20:3, Delta 8, 11, 14), Lysopc A C20:3 by Phospholipase A2
ESTRIOLATP
Transport of Estriol
GLNPROGLUr
Metabolism (Formation/Degradation) of GlnProGlu
HMR_0354
Palmitoyl Coenzyme A Hydrolase
DHEAte
Transport of 3Beta-Hydroxyandrost-5-En-17-One
PHETYRLYSr
Metabolism (Formation/Degradation) of PhetyrLys
3SPYRSP
3-sulfinopyruvate hydrolase (spotaneous reaction)
TRPTYRTYRr
Metabolism (Formation/Degradation) of Trptyrtyr
r2518
ATP-binding Cassette (ABC) TCDB:3.A.1.203.1
HMR_2007
Steroid 21-Monooxygenase
HMR_0310
Palmitoyl Coenzyme A Hydrolase
TRPSERTYRr
Metabolism (Formation/Degradation) of TrpSertyr
HMR_2344
Very-Long-Chain (3R)-3-Hydroxyacyl Coenzyme A Dehydratase
r1515
ATP-binding Cassette (ABC) TCDB:3.A.1.211.1
ASPHISCYSr
Metabolism (Formation/Degradation) of AspHisCys
RIBFLVt3o
Riboflavin transport out (ATP dependent)
PEAR_HSABCt
Transport of 1-Arachidonoyl-Sn-Glycero-3-Phosphoethanolamine
PI345P3P
Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
HISARGSERr
Metabolism (Formation/Degradation) of HisArgSer
HMR_1539
Sterol 14Alpha-Demethylase
ISOCHOLabc
Isocholic acid ABC bile acid transporter
NMNHYD
Nicotinamide ribonucleotide phosphohydrolase
ARGALATHRr
Metabolism (Formation/Degradation) of ArgAlaThr
FACOAE140
Fatty-acid-CoA thioesterase (tetradecanoate)
r0647
Spontaneous reaction
RE2541C
Beta-Glucuronidase
PCHOL2STE_HSPLA2
Formation of 2-Stearoylglycerophosphocholine by Phospholipase A2
NACASPAH
N-Acetyl-L-aspartate amidohydrolase
HMR_8580
Alpha-Amylase
C04483t1
Transport of Deoxycholate
IMACTD
Imidazole acetaldeyde dehydrogenase
HMR_2288
Stearoyl Coenzyme A 9-Desaturase
MAOX
Methylamine:oxygen oxidoreductase (deaminating) (copper-containing)
EANDRSTRNtr
Transport of 16Alpha-Hydroxydehydroepiandrosterone, Endoplasmatic Reticulum
HMR_0981
Leukotriene-B4 20-Monooxygenase
RE1807C
RE1807
PAILAR_HSPLA2
Formation of 1-Arachidonoylglycerophosphoinositol by Phospholipase A2
PE2LINL_HSPLA2
Formation of 2-Linoleoylglycerophosphoethanolamine by Phospholipase A2
GHMT2r
Glycine hydroxymethyltransferase, reversible
5HOXINDACTO2OX
5-Hydroxyindoleacetaldehyde:oxygen oxidoreductase
GLNHISLYSr
Metabolism (Formation/Degradation) of GlnHisLys
r0688
3Alpha, 7Alpha-Dihydroxy-5Beta-Cholestan-26-Al:NAD+ Oxidoreductase Bile Acid Biosynthesis
BALAVECSEC_1
B-Alanine Secretion via Secretory Vesicle (ATP Driven)
HMR_2292
Stearoyl Coenzyme A 9-Desaturase
HMR_6785
HMR 6785
ARGN
Arginase
ATPM
ATP maintenance requirement
CYSGLUHISr
Metabolism (Formation/Degradation) of CysGluHis
XOLDIOLONEATP
Transport of 7Alpha, 12Alpha-Dihydroxycholest-4-En-3-One, Active Transport
PCHOLN28_HSPLA2
Formation of Lysopc A C28:0 by Phospholipase A2
ALAARGGLYr
Metabolism (Formation/Degradation) of AlaArgGly
r1517
ATP-binding Cassette (ABC) TCDB:3.A.1.211.1
RE3167C
RE3167
HMR_2265
Very-Long-Chain (3R)-3-Hydroxyacyl Coenzyme A Dehydratase
HMR_0367
HMR 0367
LEUVALr
Metabolism (Formation/Degradation) of LeuVal
MELATNOX
Melatonin:NADP oxidoreductase
AMCOXO
2-aminomuconate reductase
5EIPENCte
Transport of 5, 8, 11, 14, 17-Eicosapentenoic Acid, Extracellular Space
SPHMYLN180241_hs_ATPt
Transport of Sphingomyelin (D18:0/24:1), Active Transport
NDP8
Nucleoside-diphosphatase (dUDP)
ILEGLNGLUr
Metabolism (Formation/Degradation) of IleGlnGlu
GALSGLT1le
Transport of D-Galactose from extracellular space to cytosol of mucosal cells in small intestine
5MTHFt2_1
5-Methyltetrahydrofolate Transport via Anion Exchange
PCHOLN205_HSPLA2
Formation of 1-Eicosapentenoylglycerophosphocholine (Delta 5, 8, 11, 14, 17), Sn1-Lpc (20:5) by Phospholipase A2
DESAT20_1
Fatty acyl-CoA desaturase (n-C20:3CoA -> n-C20:4CoA)
PYAM5PO
Pyridoxamine 5'-phosphate oxidase
PEFLIP
Phosphatidylethanolamine flippase
ASNTYRGLYr
Metabolism (Formation/Degradation) of AsntyrGly
ALAHISALAr
Metabolism (Formation/Degradation) of AlaHisAla
HISTRPHISr
Metabolism (Formation/Degradation) of HisTrpHis
HMR_1735
Cholesterol 24-Hydroxylase
LEUALAARGr
Metabolism (Formation/Degradation) of LeuAlaArg
NEU25
Sialidase, Cytosol (Neu2)
7DHCHOLabc
7-Dehydrocholic acid ABC bile acid transporter
AM4NC9CSteb
Efflux of AM4N9-cyclosporine into bile
FA160COAabcp_1
Fatty acyl-CoA peroxisomal transport via ABC system (16:0)
MTHFC
Methenyltetrahydrofolate cyclohydrolase
THEXDDte
Transport of 7Z, 10Z-Hexadecadienoic Acid into Extracellular Space
PEDH203_HSABCt
Transport of 1-Dihomo-Linolenoylglycerophosphoethanolamine (20:3, Delta 8, 11, 14)
RE2636C
RE2636
KYNATESYN
4-(2-Aminophenyl)-2,4-dioxobutanoate dehydratase
7BHGLZGLCABCt
Excretion of 7-beta-OH-gliclazide-glucuronide into bile
CE7081tm
Transport of 15(R)-HEPE, Extracellular Space, Active Transport
P4502C19
Cytochrome P450 2C19
34DHXMANDACOX
3,4-Dihydroxymandelaldehyde:NAD+ oxidoreductase
RE2069C
RE2069
NTD4
5'-nucleotidase (CMP)
CRVSM1teb
Efflux of cerivastatin-M1 into bile
ARGARGLYSr
Metabolism (Formation/Degradation) of ArgArgLys
HMR_0418
Palmitoyl Coenzyme A Hydrolase
HISGLUGLNr
Metabolism (Formation/Degradation) of HisGluGln
PCHOLLINL_HSPLA2
Formation of 1-Linoleoylglycerophosphocholine (Delta 9, 12) by Phospholipase A2
DEDOLP1_L
Dehydrodolichol diphosphate phosphatase (liver)
BIOMASS_reaction
Generic Human Biomass Reaction
r2498
ATP-binding Cassette (ABC) TCDB:3.A.1.203.3
3H3MGLTc
Formation of 3-Hydroxy-3-Methyl-Glutarate
HMR_0434
Palmitoyl Coenzyme A Hydrolase
PRGNLONEte
Transport of Pregnenolone, Extracellular
HISCYSCYSr
Metabolism (Formation/Degradation) of HisCysCys
HMR_0423
HMR 0423
HMR_1502
Methylsterol Monooxygenase
RE3251C
RE3251
HMR_6728
L-Tyrosine, Tetrahydrobiopterin:Oxygen Oxidoreductase (3-Hydroxylating)
HMR_8574
Alpha-Amylase
H2Ot
H2O transport via diffusion
HMR_0803
Alpha-Galactosidase
r1028
ATP-binding Cassette (ABC) TCDB:3.A.1.201.2
RE1709C
4A-Hydroxytetrahydrobiopterin Dehydratase
TYRTYRr
Metabolism (Formation/Degradation) of Tyrtyr
LYSGLNPHEr
Metabolism (Formation/Degradation) of LysGlnPhe
56DHPVSteb
Efflux of 3-keto-5,6,-dihydroxy-pravastatin into bile
TRPASPASPr
Metabolism (Formation/Degradation) of TrpAspAsp
SULPACMPtev
Efflux of acetaminophen-sulphate into hepatic vein
ARGLEUPHEr
Metabolism (Formation/Degradation) of ArgLeuPhe
BILDGLCURte
Bilirubin beta-diglucuronide transport MDR
THRGLNGLUr
Metabolism (Formation/Degradation) of ThrGlnGlu
HMR_0410
Palmitoyl Coenzyme A Hydrolase
6HLVSTAChep
Conversion of lactone form of 6-beta-hydroxy-lovastatin to acid form
LGNCCOAtcx_1
Transport of Lignocericyl Coenzyme A from Cytosol to Peroxisome.
FAS120COA
Fatty acyl CoA synthase n C120CoA
MVLACc
Formation of Mevalonate-Lactone
GLULEUr
Metabolism (Formation/Degradation) of GluLeu
C14771ATP
Transport of 14, 15-EET, Active Transport
TYRTHRr
Metabolism (Formation/Degradation) of TyrThr
5HTRPVESSEC_1
5-Hydroxy-L-Tryptophan Secretion via Secretory Vesicle (ATP Driven)
RE2626C
RE2626
ARGALAPHEr
Metabolism (Formation/Degradation) of ArgAlaPhe
ALDD19xr
Aldehyde dehydrogenase (phenylacetaldehyde, NAD)
GTHOXti2
Oxidized glutathione irreversible active transport (rbc)
CE4843t
Transport of Cis, Cis-11, 14-Eicosadienoyl Coenzyme A, Active Transport
DCA3Sabc
Deoxycholic acid 3-sulfate ABC bile acid transporter
SPHMYLN1824_hs_ATPt
Transport of Sphingomyelin (D18:0/24:0), Active Transport
GLUCYSte
Transport (ATP-Dependent) into Extracellular Space
CE2510t
Transport of 11-Cis-Eicosenoate
PRDX
Peroxidase (multiple substrates)
RNTR1
Ribonucleoside triphosphate reductase ATP
ESTRONEte
Transport of Estrone, Extracellular
5OHFVSteb
Efflux of 5-hydroxy-fluvastatin into bile for excretion into faeces
FADDP
FAD diphosphatase
3DHDCAS
3-dehydro-deoxycholic acid formation
PCHOLAR_HSABCt
Transport of 1-Arachidonoyl-Glycero-3-Phosphocholine
C05463t1
Transport of Taurodeoxycholate
PGLc
6-Phosphogluconolactonase
MLTHFte1
Transport by ABCa11 into Extracellular Space
HPDECEte
Transport of Trans-Delta-2-Heptadecanoic Acid, Extracellular
PE203_HSPLA2
Formation of 1-Eicosatrienoylglycerophosphoethanolamine (Delta 11, 14, 17), Lpe (20:3) by Phospholipase A2
RE3172C
RE3172
PE226_HSPLA2
Formation of 1-Docosahexenoylglyceroethanolamine (Delta 4, 7, 10, 13, 16, 19), Lpe (22:6) by Phospholipase A2
LCA3Sabc
Lithocholic acid 3-sulfate ABC bile acid transporter
HMR_0290
Palmitoyl Coenzyme A Hydrolase
PCHOLN183_HSPLA2
Formation of 1-Octadeca-Trienoylglycerophosphocholine, Sn1-Lpc (18:3, Delta 9, 12, 15) by Phospholipase A2
AM1ACSteb
Efflux of AM1A-cyclosporine into bile
NEU24
Sialidase, Cytosol (Neu2)
HMR_1948
17Alpha-Hydroxypregnenolone, Hydrogen-Donor:Oxygen Oxidoreductase (21-Hydroxylating)
HMR_6874
L-Tyrosine, L-Dopa:Oxygen Oxidoreductase
TRPLYSr
Metabolism (Formation/Degradation) of TrpLys
CE7082ATP
Transport of 15(S)-HEPE, Active Transport
CE2445t
Transport of 6-Trans-Leukotriene B4, Active Transport
PCHOLPALME_HSABCt
Transport of 1-Palmitoleoylglycerophosphocholine (Delta 9)
PI45P5P
Phosphatidylinositol-4,5-bisphosphate 5-phosphatase
LFORKYNHYD
L-Formylkynurenine hydrolase
HMR_0641
Acetylcholinesterase
PRISTCOAtcx
Transport of pristanoylcoa from cytosol to peroxisomes.
HMR_1739
7Alpha-Hydroxycholest-4-En-3-One 12Alpha-Hydroxylase
PROPHEr
Metabolism (Formation/Degradation) of ProPhe
LPS3
Lipase
HMR_2261
Very-Long-Chain (3R)-3-Hydroxyacyl Coenzyme A Dehydratase
NTD1
5'-nucleotidase (dUMP)
HMR_1516
HMR 1516
PCFLOPm
Phosphatidylcholine flippase
PTRCOX1
Putrescine:oxygen oxidoreductase (deaminating)
CE1352te
Transport of 17Alpha-Hydroxypregnenolone Sulfate, Extracellular
TRPHISMETr
Metabolism (Formation/Degradation) of TrpHisMet
HMR_0307
HMR 0307
PYDXDH
Pyridoxal dehydrogenase
RE3231C
RE3231
HMR_0415
HMR 0415
GLC3MEACPtev
Efflux of glucuronide-conjugate of 3-methoxy-acetaminophen into hepatic vein
P4502C93
Cytochrome P450 2C9
SPHMYLN18115_hs_ATPt
Transport of Sphingomyelin (D18:1/15:0), Active Transport
PCHOLN204_HSABCt
Transport of 1-Eicosatetraenoylglycerophosphocholine (Delta 8, 11, 14, 17), Sn1-Lpc (20:4)
GLYVESSEC_1
Secretion of Glycine via Secretory Vesicle (ATP Driven)
PCHOLSTE_HSABCt
Transport of 1-Stearoylglycerophosphocholine
RE1834C
Palmitoyl Coenzyme A Hydrolase
GLNHISHISr
Metabolism (Formation/Degradation) of GlnHisHis
PCHOLN201_HSPLA2
Formation of 1-Eicosenoylglycerophosphocholine (Delta 11) , Sn1-Lpc (20:1) by Phospholipase A2
5HOXINOXDA
5-Hydroxytryptamine:oxygen oxidoreductase(deaminating)(flavin-containing)
TYROXDAc
Tyramine:oxygen oxidoreductase(deaminating)(flavin-containing) (cytosol)
HMR_7197
HMR 7197
r0558
Gentisate aldehyde:NAD+ oxidoreductase Tyrosine metabolism EC:1.2.1.29
HMR_0253
HMR 0253
HMR_0299
HMR 0299
GLNLYSLYSr
Metabolism (Formation/Degradation) of GlnLysLys
HMR_4700
N, N-Dimethylglycine:Electron-Transfer Flavoprotein Oxidoreductase (Demethylating)
TTDCEAc
Hydrolysis of Fatty Acyl Coenzyme A (14:1)
RADH3
Retinal dehydrogenase
UDPGD
UDPglucose 6-dehydrogenase
PCHLN225_HSABCt
Transport of 1-Docosahexenoylglycerophosphocholine (Delta 4, 7, 10, 13, 16, 19), Sn1-Lpc (22:6)
SERARGALAr
Metabolism (Formation/Degradation) of SerArgAla
TXB2t
Transport of Thromboxane B2
CE7083t
Transport of Leukotriene B5, Active Transport
PI45P4P
Phosphatidylinositol-4,5-bisphosphate 4-phosphatase
CE2006te
Transport (ATP-Dependent) into Extracellular Space
CYP2R1
Vitamin D3 25-hydroxylase
TRPTYRGLNr
Metabolism (Formation/Degradation) of TrptyrGln
r1525
ATP-binding Cassette (ABC) TCDB:3.A.1.211.1
RE2155C
Steroid 21-Monooxygenase
DESAT16
Palmitoyl CoA desaturase n C160CoA n C161CoA
AHCi
Adenosylhomocysteinase
DESAT16_2
Palmitoyl-CoA desaturase (n-C16:0CoA -> n-C16:1CoA)
3DHLCAabc
3-dehydro-lithocholic acid ABC bile acid transporter
ASPPROLYSr
Metabolism (Formation/Degradation) of AspProLys
RE1096C
RE1096
HMR_6558
Phosphatidylinositol-3, 4, 5-Trisphosphate 3-Phosphatase
SPHMYLN_HsATPte
Extracellular Transport of Sphingomyeline, Active Transport
HMR_1557
HMR 1557
ACNAM9PL2
N-Acetylneuraminate 9-phosphate pyruvate-lyase (pyruvate-phosphorylating)
PPBNGS
Porphobilinogen synthase
PROASNCYSr
Metabolism (Formation/Degradation) of ProAsnCys
RE3411C_1
RE3411C
TSACMSULtev
Efflux of thiomethyl-sulphoxide-acetaminophen-sulphate into hepatic vein
HMR_0430
Palmitoyl Coenzyme A Hydrolase
ASPMETASPr
Metabolism (Formation/Degradation) of AspMetAsp
r0145
L-Arginine, NADPH:Oxygen Oxidoreductase (Nitric-Oxide-Forming)
SPHMDAc
Sphingomyelin deacylase
DES21
Sphingolipid C-4 Hydroxylase (Des2)
RIBFLVt3
Riboflavin transport (ATP dependent)
CE2537ABCt
Transport of 15-Hydroxy- (8Z, 11Z, 13E)-Eicosatrienoate, Active
HMR_1838
Lithocholic acid 1beta-hydroxylase
PCHOL2OLE_HSABCt
Transport of 2-Oleoylglycerophosphocholine
CYSASPPHEr
Metabolism (Formation/Degradation) of CysAspPhe
RE2346C
RE2346
RE2235C
Unspecific Monooxygenase
PSFLIPm
Phosphatidylserine flippase
DPGase
Diphosphoglycerate phosphatase
UCHOLabc
Ursocholic acid ABC bile acid transporter
ENO
Enolase
RE3346C
Aldehyde Dehydrogenase (NAD+)
HMR_0346
Palmitoyl Coenzyme A Hydrolase
DESAT18_9
Linoleoyl-CoA, hydrogen-donor:oxygen oxidoreductase
TRPGLYASPr
Metabolism (Formation/Degradation) of TrpGlyAsp
CAPROICc
Formation of Hexanoic Acid
BAMPPALDOX
Beta-Aminopropion aldehyde NAD+ oxidoreductase
r1536
ATP-binding Cassette (ABC) TCDB:3.A.1.208.7
DESAT18_3
Stearoyl-CoA desaturase (n-C18:0CoA -> n-C18:1CoA)
LEUPROARGr
Metabolism (Formation/Degradation) of LeuProArg
GLPASE2
Glycogen phosphorylase (amyls -> glc-D)
RADH2
Retinal dehydrogenase (NADPH)
PAN4PP
Phosphatase (pan4p)
NTPP2
Nucleoside triphosphate pyrophosphorylase (gtp)
HMR_2368
Linoleoyl Coenzyme A, Ferrocytochrome B5:Oxygen Oxidoreductase (6, 7 Cis-Dehydrogenating)
HMR_2193
Very-Long-Chain (3R)-3-Hydroxyacyl Coenzyme A Dehydratase
PCHOLPALME_HSPLA2
Formation of 1-Palmitoleoylglycerophosphocholine (Delta 9) by Phospholipase A2
HKt
H+/K+ gastric/non-gastric P-ATPase and ABC ATPase
PHELEUASPr
Metabolism (Formation/Degradation) of PheLeuAsp
PCHOLP_hs
Choline phosphatase
DKMPPD
2,3-diketo-5-methylthio-1-phosphopentane degradation reaction
HMR_0598
Phosphatidate Phosphatase
PCHOLN261_HSPLA2
Formation of Lysopc A C26:1 (Delta 5) by Phospholipase A2
RE3181C
RE3181C
DESAT18
Stearoyl CoA desaturase n C180CoA n C181CoA
HMR_4771
HMR 4771
DCSPTN1COAtxc
Transport of docosapentenoylcoa into peroxisomes.
ALDD20x
Aldehyde dehydrogenase (indole-3-acetaldehyde, NAD)
HMR_0378
Palmitoyl Coenzyme A Hydrolase
TRPILELYSr
Metabolism (Formation/Degradation) of TrpIleLys
VALPHEARGr
Metabolism (Formation/Degradation) of ValPheArg
HMR_0201
Palmitoyl Coenzyme A Hydrolase
PHELYSALAr
Metabolism (Formation/Degradation) of PheLysAla
H2OGLYAQPt
Water And Glycerol Transport by Aqp
HMR_0257
HMR 0257
r1533_1
ATP-Binding Cassette (ABC) Tcdb:3.A.1.208.15
DIGALSGALSIDEATPte
Extracellular Transport of Digalactosylceramidesulfate, Active Transport
ALALYSTHRr
Metabolism (Formation/Degradation) of AlaLysThr
TYRVALMETr
Metabolism (Formation/Degradation) of TyrValMet
TSACGLUCtev
Efflux of thiomethyl-sulphoxide-acetaminophen-glucuronide into hepatic vein
SULFOX
Sulfite oxidase
RE3422C
RE3422
UAG2EMA
UDP-N-acetyl-D-glucosamine 2-epimerase (Hydrolysis)
NTPP10
Nucleoside triphosphate pyrophosphorylase (ditp)
FAOXOHC22C22DCc
Fatty Acid Omega Oxidation (W-Ohc22->C22Dc)
FTHFDH
10-formyltetrahydrofolate:NADP+ oxidoreductase
FBP26
Fructose 2 6 bisphosphate 2 phosphatase
TRPPROLEUr
Metabolism (Formation/Degradation) of TrpProLeu
CE5072te
Transport of 21-Hydroxyallopregnanolone, Extracellular
GTPCI
GTP cyclohydrolase I
DOPAVESSEC_1
Secretion of Dopamine via Secretory Vesicle (ATP Driven)
ARGARGMETr
Metabolism (Formation/Degradation) of ArgArgMet
NTPP9
Nucleoside triphosphate pyrophosphorylase (itp)
2DR1PP
2-deoxy-D-ribose 1-phosphate phosphorylase
NFDLAChc
Lactonization of hydroxy metabolite of nifedipine in hepatocytes
ASPALAARGr
Metabolism (Formation/Degradation) of AspAlaArg
C14768ATP
Transport of 5, 6-EET, Active Transport
C05302te
Transport of 2-Methoxyestradiol-17Beta, Extracellular
LEUTYRTYRr
Metabolism (Formation/Degradation) of Leutyrtyr
IBUP_RCYPCARhep
Oxidation of R-3-hydroxy ibuprofen to R-carboxy ibuprofen
HMR_0807
Beta-N-Acetylhexosaminidase
4HATVACIDhc
Conversion of 4-hydroxy-atorvastatin-lactone to its acid form in hepatocytes
HMR_1550
Methylsterol Monooxygenase
HISASPr
Metabolism (Formation/Degradation) of HisAsp
SMVtu
Efflux of simvastatin by P-gp from the enterocytes into lumen
NADDP
NAD diphosphatase
CE7096te
Transport (ATP-Dependent) into Extracellular Space
HISLYSALAr
Metabolism (Formation/Degradation) of HisLysAla
GTHRDH_syn
Glutathione hydralase (periplasmic)
HMR_1332
HMR 1332
TRPLEUVALr
Metabolism (Formation/Degradation) of TrpLeuVal
H2Oter
H2O endoplasmic reticulum transport
VITEtl
Efflux of alpha-Tocopherol into the lyphatics in chylomicrons
6AHGLZABCt
Excretion of 6-alpha-OH-gliclazide into bile
RE3437C
RE3437
PCHOLN2254_HSPLA2
Formation of 1-Docosapentenoylglycerophosphocholine (Delta 4, 7, 10, 13, 16), Sn1-Lpc (22:5)-W6 by Phospholipase A2
ACNAM9PL
N-Acetylneuraminate 9-phosphate pyruvate-lyase (pyruvate-phosphorylating)
RE0918C
Steryl-Sulfatase
12HTACRtu
Efflux of 12-hydroxy tacrolimus into intestinal lumen by ABC transporter
DADA
Deoxyadenosine deaminase
THMPPtm_cho
Thiamine diphosphate transport in via anion antiport, mitochondria
HMR_0256
Palmitoyl Coenzyme A Hydrolase
PROGLNPROr
Metabolism (Formation/Degradation) of ProGlnPro
OPAH
5-Oxoproline amidohydrolase (ATP-hydrolysing) (ir)
HMR_0239
HMR 0239
PCHOLHEP_HSABCt
Transport of 1-Heptadecanoylglycerophosphocholine
ARGCYSGLYr
Metabolism (Formation/Degradation) of ArgCysGly
GLUMETr
Metabolism (Formation/Degradation) of GluMet
HMR_1126
Leukotriene-B4 20-Monooxygenase
C05298te
Transport of 2-Hydroxyestrone, Extracellular
UDCA3Sabc
Ursodeoxycholic acid 3-sulfate ABC bile acid transporter
C05769te
Transport by Atb Binding Cassette Transporter ABCc2 into Extracellular Space
STRDNCCOAtxc
Transport of stearidonylcoa into peroxisomes.
CBPS
Carbamoyl-phosphate synthase (glutamine-hydrolysing)
6OHFVSteb
Efflux of 6-hydroxy-fluvastatin into bile for excretion into faeces
HMR_0439
HMR 0439
6HSMVACIDteb
Efflux of 6-beta-hydroxy simvastatin acid into bile
DPCOAPP
Pyrophasphatase (dephospho-CoA)
r1026
ATP-binding Cassette (ABC) TCDB:3.A.1.201.2
NTD5
5'-nucleotidase (dTMP)
RE3352C
RE3352C
H2Otly
H2O transport, lysosomal
METGLNTYRr
Metabolism (Formation/Degradation) of MetGlntyr
CE1447te
Transport (ATP-Dependent) into Extracellular Space
C05299te
Transport of 2-Methoxyestrone, Extracellular
PAFABCt
Transport of 1-Alkyl 2-Acteylglycerol 3-Phosphocholine
SERPHELYSr
Metabolism (Formation/Degradation) of SerPheLys
r1519
ATP-binding Cassette (ABC) TCDB:3.A.1.211.1
BIOMASS_maintenance
Biomass maintenance reaction without replication precursors
TRPPHEr
Metabolism (Formation/Degradation) of TrpPhe
GLYSARCNc
Hydrolysis of glycylsarcosine for uptake
PROGLULYSr
Metabolism (Formation/Degradation) of ProGluLys
PROTRPLYSr
Metabolism (Formation/Degradation) of ProTrpLys
17AHPRGNLONEte
Transport of 17Alpha-Hydroxypregnenolone, Extracellular
r0510
Steroyl Coenzyme A, Hydrogen-Donor:Oxygen Oxidoreductase Polyunsaturated Fatty Acid Biosynthesis
RE1826C
RE1826
2HATVACIDGLUCteb
Efflux of 2-hydroxy-atorvastatin-acyl-glucuronide into bile
RE1835C
Palmitoyl Coenzyme A Hydrolase
AACTOOR
Aminoacetone:oxygen oxidoreductase(deaminating)(flavin-containing)
FPGS4_1
Folylpolyglutamate Synthetase (Dhf)
FACOAE60
Fatty-acid-CoA thioesterase (hexanoate)
AHANDROSTANGLCte
Glucuronidated compound transport
HMR_2349
Very-Long-Chain (3R)-3-Hydroxyacyl Coenzyme A Dehydratase
XAND
Xanthine dehydrogenase
PCHOLN15_HSABCt
Transport of 1-Pentadecanoylglycerophosphocholine, Sn1-Lpc (15:0)
FOLABCCte
Folate Transport by ABCa11
P4502C9
Cytochrome P450 2C9
56EPPVSteb
Efflux of 5,6-epoxy-3-alpha-iso-pravastatin into bile
3HLVSTACtbc
Release of 3-hydroxy-lovastatin acid form into bile
UREAt5
Urea, water cotransport
ARTCOAL3_cho
R group coenzyme a ligase
PCHOLAR_HSPLA2
Formation of 1-Arachidonoyl-Glycero-3-Phosphocholine by Phospholipase A2
THRASNTYRr
Metabolism (Formation/Degradation) of ThrAsntyr
HMR_2218
Very-Long-Chain (3R)-3-Hydroxyacyl Coenzyme A Dehydratase
3MOX4HOXPGALDOX
3-Methoxy-4-hydroxyphenylglycolaldehyde:NAD+ oxidoreductase
TDP
Thiamin pyrophosphatase
MI134PP
D-myo-Inositol 1,3,4-trisphosphate 1-phosphohydrolase
HMR_6607
HMR 6607
RE3153C
RE3153
HISGLNALAr
Metabolism (Formation/Degradation) of HisGlnAla
FBP
Fructose-bisphosphatase
ESTROSABCCte
Estrone-Sulphate Transport by ABCa11
PHYQt
Phylloquinone transport
TRPTHRTYRr
Metabolism (Formation/Degradation) of TrpThrtyr
LEUASNASPr
Metabolism (Formation/Degradation) of LeuAsnAsp
ILEASNHISr
Metabolism (Formation/Degradation) of IleAsnHis
HMR_0629
Phospholipase D
HMR_2284
Stearoyl Coenzyme A 9-Desaturase
TXB2c
Formation of Thromboxane B2
DOPA4GLCURt
Dopamine 4-O-Glucuronide Transport
6HMSMVACIDteb
Efflux of 6-beta-hydroxy-methyl-simvastatin-acid into bile
AM1CCSteb
Efflux of AM1c-cyclosporine into bile
FAS100COA
Fatty acyl CoA synthase n C100CoA
ANDRSTANDRte
Transport of 5Alpha-Androstane-3, 17-Dione, Extracellular
LTA4H
Leukotriene A-4 hydrolase
PCHOLOLE_HSPLA2
Formation of 1-Oleoylglycerophosphocholine (Delta 9) by Phospholipase A2
Am1CSAteb
Efflux of AM1-cyclosporine into bile
HDCA6Gte
Glucuronidated bile acid excretion (HDCA-6G)
3HPVSTEThc
3HPVSTEThc
PROHISTYRr
Metabolism (Formation/Degradation) of ProHistyr
PCHOLDET_HSPLA2
Formation of 1-Eicosatrienoylglycerophosphocholine (Delta 11, 14, 17) by Phospholipase A2
NTD7
5'-nucleotidase (AMP)
STS1
Steryl-sulfatase
HMR_0363
HMR 0363
ALDD19x_P
Aldehyde dehydrogenase (phenylacetaldehyde, NADP)
PEPALM_HSASBCt
Transport of 1-Palmitoylglycerophosphocholine
RE1836C
Propionyl Coenzyme A C2-Trimethyltridecanoyltransferase
RE2644C
Aspartoacylase
6HSMVACIDhep
Conversion of 6-beta-hydroxy simvastatin lactone to acid form
RE3176C
RE3176
HMR_2495
HMR 2495
BILGLCURte
Bilirubin monoglucuronide transport MDR
HMR_6839
Steryl-Sulfatase
HMR_4782
HMR 4782
THMTP
Thiamine-triphosphatase
ALR
Aldose reductase
LYSARGLEUr
Metabolism (Formation/Degradation) of LysArgLeu
HMR_1545
Methylsterol Monooxygenase
HMR_0317
HMR 0317
HMR_0395
HMR 0395
NT5C
5'-nucleotidase
GMAND
GDP-D-mannose dehydratase
AM4NCSteb
Efflux of AM4N-cyclosporine into bile
12HARACHDte
Transport of 12 Hydroxy Arachidonic Acid, Extracellular Space, Active Transport
PPAP
Phosphatidic acid phosphatase
NDP1
Nucleoside diphosphatase ADP
SPMDOX
Spermidine:(acceptor) oxidoreductase
HMR_0795
Sphingomyelin Phosphodiesterase
PSP_L
Phosphoserine phosphatase (L-serine)
AASAD3
L-aminoadipate-semialdehyde dehydrogenase (NADH)
PDE4
3',5'-cyclic-nucleotide phosphodiesterase
21HPRGNLONEt1
Transport of 21-Hydroxypregnenolone, Active Transport
MI34PP
D-myo-Inositol-3,4-bisphosphate 4-phosphohydrolase
31DMTtu
Efflux of 31-O-desmethyl tacrolimus into intestinal lumen by ABC transporter
SMPD4
Sphingomyelinase
PCHOLDEIC_HSPLA2
Formation of 1-Eicosadienoylglycerophosphocholine (Delta 11, 14) by Phospholipase A2
HMR_2281
Stearoyl Coenzyme A 9-Desaturase
RE3568C
RE3568
PVSGLUCteb
Efflux of pravastatin glucuronide into bile
THRNTt
Transport of L-Threonate by Active Transport
HISMETr
Metabolism (Formation/Degradation) of HisMet
34DHXMANDACOX_NADP
3,4-Dihydroxymandelaldehyde:NADP+ oxidoreductase
HMR_0830
Beta-Galactosidase
ASNTYRTHRr
Metabolism (Formation/Degradation) of AsntyrThr
FAH3_1
Fatty Acid Omega-Hydroxylase
RE0578C
Palmitoyl Coenzyme A Hydrolase
TDCA3Sabc
Taurodeoxycholic acid 3-sulfate ABC bile acid transporter
RE1134C
RE1134
RE3243C
RE3243
HMR_1989
Steroid, Reduced-Adrenal-Ferredoxin:Oxygen Oxidoreductase (11-Hydroxylating)
FAS180COA
Fatty acyl CoA synthase n C180CoA
r1532_1
ATP-Binding Cassette (ABC) Tcdb:3.A.1.208.15
4HOXPACDOX_NADP
4HOXPACDOX LPAREN NADP RPAREN
HMR_8570
Alpha-Amylase
1531TACRteb
Efflux of 15, 31-O-Didesmethyl-tacrolimus into bile
6BHGLZGLCABCt
Excretion of 6-beta-OH-gliclazide-glucuronide into bile
GBA
Glucosylceramidase
PCHOLN204_HSPLA2
Formation of 1-Eicosatetraenoylglycerophosphocholine (Delta 8, 11, 14, 17), Sn1-Lpc (20:4) by Phospholipase A2
TRPGLNGLNr
Metabolism (Formation/Degradation) of TrpGlnGln
PVSATPtu
Pravastatin efflux into lumen for excretion into feces
CA3Sabc
Cholic acid 3-sulfate ABC bile acid transporter
HMR_0281
HMR 0281
FAOXOHC16C16DCc
Fatty Acid Omega Oxidation (W-Ohc16->C16Dc)
PTVSTATPtu
Efflux of pitavastatin by BCRP from the enterocytes into lumen
CE2510ABCt
Transport of 11-Cis-Eicosenoate, Active
P4502C8
Cytochrome P450 2C8
HMR_0387
HMR 0387
HMR_7256
Dolichyl-Diphosphate Phosphohydrolase
RE3301C_1
Phospholipase D
P4502C92
Cytochrome P450 2C9
HMR_0287
HMR 0287
7OHOCTAc
Formation of 7-Hydroxy-Octanoate
ADPRDP
ADPribose diphosphatase
DESAT18_6
Fatty acyl-CoA desaturase (n-C18:1CoA -> n-C18:2CoA)
PCHOLMYR_HSPLA2
Formation of 1-Myristoylglycerophosphocholine by Phospholipase A2
PEDH17_HSPLA2
Formation of 1-Heptadecanoylglycerophosphoethanolamine (C17:0 Pe) by Phospholipase A2
HMR_1493
Methylsterol Monooxygenase
HMR_0406
Palmitoyl Coenzyme A Hydrolase
PDE1
3',5'-cyclic-nucleotide phosphodiesterase
WHARACHDt
Transport of W-Hydroxyl Arachidonic Acid, Active Transport
SPHMYLN18122_hs_ATPt
Transport of Sphingomyelin (D18:1/22:0), Active Transport
1513TACRtu
Efflux of 13,15-O-didesmethyl tacrolimus into intestinal lumen by ABC transporter
PEFLIPm
Phosphatidylethanolamine flippase
METPHEARGr
Metabolism (Formation/Degradation) of MetPheArg
DESAT24_1
Fatty acyl-CoA desaturase (n-C24:5CoA -> n-C24:6CoA)
DHORTS
Dihydroorotase
RE3273C_1
Phospholipase D
ESTRADIOLGLCt2
17-beta-D-glucuronide transport (ATP-dependent)
CE2047te
Transport (ATP-Dependent) into Extracellular Space
r2502
ATP-binding Cassette (ABC) TCDB:3.A.1.203.3
3MOXTYRESSte
3-Methoxytyramine secretion via secretory vesicle (ATP driven)
MALT
Alpha glucosidase
5ADTSTSTERONEGLCte
Glucuronidated compound transport
HDCA24Gte
Glucuronidated bile acid excretion (HDCA-24G)
LYSTRPARGr
Metabolism (Formation/Degradation) of LysTrpArg
FACOAE120
Fatty-acid-CoA thioesterase (dodecanoate)
ILEASPr
Metabolism (Formation/Degradation) of IleAsp
ACTNMO
Acetone monooxygenase
PGL
6-phosphogluconolactonase
TRPGLULEUr
Metabolism (Formation/Degradation) of TrpGluLeu
H2Otg
H2O transport, Golgi apparatus
VALSERARGr
Metabolism (Formation/Degradation) of ValSerArg
RE0908C
Steryl-Sulfatase
RE3493C
RE3493
IBUPGLUCtpvb
Release of iboprofen acyl glucuronides into the portal blood
NEU22
Sialidase, Cytosol (Neu2)
FCOAH2
Formyl coa hydrolase
STS3
Steryl-sulfatase
PESTE_HSABCt
Transport of 1-Stearoylglycerophosphoethanolamine
PEDH161_HSPLA2
Formation of 1-Hexadecenoylglycerophosphoethanolamine (C16:1 Pe, Delta 9) by Phospholipase A2
HMR_2457
Unspecific Monooxygenase
BUP2
Beta-ureidopropionase (D-3-amino-isobutanoate forming)
HISPROLYSr
Metabolism (Formation/Degradation) of HisProLys
NTD11
5'-nucleotidase (IMP)
SPHMYLN18118_hs_ATPt
Transport of Sphingomyelin (D18:1/18:0), Active
NADS2
Nicotinate-mononucleotide adenylyltransferase
ACHVESSEC_1
Acetylcholine Secretion via Secretory Vesicle (ATP Driven)
RE2948C
RE2948
ALAALACNc
Hydrolysis of Alanylalanine
VALLEUPHEr
Metabolism (Formation/Degradation) of ValLeuPhe
NOS2
Nitric Oxide Synthase (NO forming)
METHSUCC
Formation of Methyl-Succinate
CYSTS
Cystathionine beta synthase
AM1ALCSteb
Efflux of AM1AL-cyclosporine into bile
PELINL_HSPLA2
Formation of 1-Linoleoylglycerophosphoethanolamine (Delta 9, 12) by Phospholipase A2
GLYLEUHYDROc
Hydrolysis of Glycylleucine in the small intestine for cellular uptake
HMR_2435
Very-Long-Chain (3R)-3-Hydroxyacyl Coenzyme A Dehydratase
3DHCAS
3-dehydrocholic acid formation
NABTNO
N4 AcetylaminobutanalNAD oxidoreductase
LEUASPLYSr
Metabolism (Formation/Degradation) of LeuAspLys
HMR_2403
HMR 2403
HMR_2296
Stearoyl Coenzyme A 9-Desaturase
HMR_2287
Stearoyl Coenzyme A 9-Desaturase
NBAHH_ir
Nalpha-(beta-alanyl)-L-histidine hydrolase IR
RE2426C
RE2426
PEAMNO
Phenethylamine oxidase
r1516
ATP-binding Cassette (ABC) TCDB:3.A.1.211.1
HMR_0343
HMR 0343
FACOAE160
Fatty-acid-CoA thioesterase (hexadecanoate)
PROARGASPr
Metabolism (Formation/Degradation) of ProArgAsp
ILETRPTYRr
Metabolism (Formation/Degradation) of IleTrptyr
DESAT18_10
Fatty acyl-CoA desaturase (n-C18:2CoA -> n-C18:3CoA)
GLYVALHISr
Metabolism (Formation/Degradation) of GlyValHis
TTDCEAATP
Active Transport of Tetradecenoate (N-C14:1)
ISOLVSTtbc
Release of 3-hydroxy-iso-delta-4,5-hydroxy acid form of lovastatin into bile
RE2112C
RE2112
HMR_0303
HMR 0303
ADD
Adenine deaminase
PROARGCYSr
Metabolism (Formation/Degradation) of ProArgCys
ASPLYSGLUr
Metabolism (Formation/Degradation) of AspLysGlu
SPHMYLN181221_hs_ATPt
Transport of Sphingomyelin (D18:1/22:1), Active
ARTCOAL2_cho
R group coenzyme a ligase
21HPRGNLONE
Formation of 21-Hydroxypregnenolone
ESTRAABCtc
17Beta-Estradiol 3-Glucosiduronic Acid Transport by ABCa8
ARGHISTHRr
Metabolism (Formation/Degradation) of ArgHisThr
AM9CSAteb
Efflux of AM9-cyclosporine into bile
CDCA24Gte
Glucuronidated bile acid excretion (CDCA-24G)
MI1345PP
D-myo-Inositol 1,3,4,5-tetrakisphosphate 5-phosphohydrolase
ACMPthc
Uptake of acetaminophen by the hepatocytes
EIC21114TRte
Transport of Trans, Cis, Cis-2, 11, 14-Eicosatrienoic Acid
ARGARGr
Metabolism (Formation/Degradation) of ArgArg
THMTPt_1
Thiamine Triphosphate Transport in via Anion Antiport
4HATVACIDteb
Efflux of 4-hydroxy-atorvastatin-acid into bile
GLUMETHISr
Metabolism (Formation/Degradation) of GluMetHis
PHEPHEASNr
Metabolism (Formation/Degradation) of PhePheAsn
AMPDA
Adenosine monophosphate deaminase
ADPMAN
ADPmannose diphosphatase
HMR_0306
Palmitoyl Coenzyme A Hydrolase
LSTNtu
Efflux of losartan by P-gp from the enterocytes into lumen
PEDH13_HSPLA2
Formation of 1-Tridecanoylglycerophosphoethanolamine (C13:0 Pe) by Phospholipase A2
HMR_0194
HMR 0194
METASNTYRr
Metabolism (Formation/Degradation) of MetAsntyr
34DHALDD
Aldehyde dehydrogenase 3 4 dihydroxyphenylacetaldehyde NAD
AM6SAD
Aminomuconate-semialdehyde dehydrogenase
ETHMALACc
Formation of Ethylmalonic Acid
NEU21
Sialidase, Cytosol (Neu2)
TYRASPARGr
Metabolism (Formation/Degradation) of TyrAspArg
LEULEUTRPr
Metabolism (Formation/Degradation) of LeuLeuTrp
P4502E1
Cytochrome P450 2E1
ESTRONEGLCt
ABC transporter
LTHSTRLABCt
Transport of Lathosterol, Energy Dependant
NADPN
NADP nucleosidase
PEOLE_HSABCt
Transport of 1-Oleoylglycerophosphoethanolamine (Delta 9)
PIPLC
Phosphatidylinositol phospholipase C
ARGGLUPROr
Metabolism (Formation/Degradation) of ArgGluPro
r1384
Guanosine aminohydrolase EC:3.5.4.15
FAS180
Fatty acid synthase n C180
PROVALGLNr
Metabolism (Formation/Degradation) of ProValGln
PEOLE_HSPLA2
Formation of 1-Oleoylglycerophosphoethanolamine (Delta 9) by Phospholipase A2
AMPTASECG
Alanyl aminopeptidase (cys-gly)
HMR_1754
Cholate Coenzyme A Ligase
PMI12346PH
5 diphosphoinositol 1 2 3 4 6 pentakisphosphate diphosphohydrolase
ASNN
L-asparaginase
HMR_1479
Sterol 14Alpha-Demethylase
ACMPGLUTtep
Efflux of acetaminophen-glutathione-conjugate from enterocytes into portal blood
PCHOLSTE_HSPLA2
Formation of 1-Stearoylglycerophosphocholine by Phospholipase A2
TETDECA511ACt
Transport of Cis-5, 8-Tetradecadienoic Acid, Active Transport
HMR_1992
11Beta-Hydroxyprogesterone, Hydrogen-Donor:Oxygen Oxidoreductase (21-Hydroxylating)
MI134P4P
Inositol-1,3,4-trisphosphate 4-phosphatase
MI145PP
D-myo-Inositol-1,4,5-trisphosphate 5-phosphohydrolase
THRILEARGr
Metabolism (Formation/Degradation) of ThrIleArg
7KLITCHOLc
Formation of 7-Ketolithocholate
PHETYRr
Metabolism (Formation/Degradation) of Phetyr
LYSVALTRPr
Metabolism (Formation/Degradation) of LysValTrp
PCHOLEIC_HSABCt
Transport of 1-Eicosadienoylglycerophosphocholine (Delta 11, 14)
ASNMETPROr
Metabolism (Formation/Degradation) of AsnMetPro
RE3434C
Leukotriene-B4 20-Monooxygenase
CAATPS_1
Ca ATPase
THMMPtm_cho
Thiamine monophosphate transport, mitochondrial
CSND
Cytosine deaminase
EANDRSTRNte
Transport of 16Alpha-Hydroxydehydroepiandrosterone, Extracellular
4PYRDX
4-Pyridoxal secretion
PCHOLN1836_HSPLA2
Formation of 1-Octadeca-Trienoylglycerophosphocholine, Sn1-Lpc (18:3, Delta 6, 9, 12) by Phospholipase A2
FAEL204
Fatty-acyl-CoA elongation (n-C20:4CoA)
PYDXO_1
Pyridoxamine:oxygen oxidoreductase (deaminating)
35DSMVteb
Efflux of 3,5-dihydrodiol-simvastatin-lactone form into bile
HMR_0214
Palmitoyl Coenzyme A Hydrolase
HMR_0382
Palmitoyl Coenzyme A Hydrolase
ASCBSVCTtc
Transport of L-Ascorbate by SVCT1 or SVCT2 transporter
TCHOLAt3
ABC bile acid transporter
HMR_2355
Very-Long-Chain (3R)-3-Hydroxyacyl Coenzyme A Dehydratase
MEPIVESSte_cho
Metanephrine secretion via secretory vesicle (ATP driven)
HMR_0642
Phospholipase D
3HPPPNOHc
Hydroxylation of 3- (3-Hydroxyphenyl)Propionate
TYRCYSTHRr
Metabolism (Formation/Degradation) of TyrCysThr
NORMETEVESSte
L-Normetanephrine seceretion via secretory vesicle (ATP driven)
HMR_9805
Sn-Glycero-3-Phosphocholine Cholinephosphohydrolase
LEULEULAPc
Hydrolysis of Leucylleucine in the small intestine for cellular uptake
ALDD2y
Aldehyde dehydrogenase (acetaldehyde, NADP)
PEDH12_HSPLA2
Formation of 1-Didecanoylglycerophosphoethanolamine (C12:0 Pe) by Phospholipase A2
MI14PP
D-myo-Inositol-1,4-bisphosphate 1-phosphohydrolase
DSPVSteb
Efflux of desacyl dehydro-pravastatin into bile
HMR_2282
Stearoyl Coenzyme A 9-Desaturase
FUMAC
Fumarylacetoacetase
GCA3Sabc
Glycocholic acid 3-sulfate ABC bile acid transporter
3DHLCAS
3-dehydro-lithocholic acid formation
PRISTte
Transport (ATP-Dependent) into Extracellular Space
LYSPHEILEr
Metabolism (Formation/Degradation) of LysPheIle
6CSMVACIDhep
Conversion of 6-beta-carboxy simvastatin lactone to acid form
ANDRSTNDNte
Transport of Androst-4-Ene-3, 17-Dione, Extracellular
RE0915C
Alpha-Amylase
METARGLEUr
Metabolism (Formation/Degradation) of MetArgLeu
CE7172ATP
Transport of 14, 15-DIHETE, Active Transport
TYRALAPHEr
Metabolism (Formation/Degradation) of TyrAlaPhe
COPROSTabc
Coprostanol ABC bile acid transporter
MLTG1
Maltodextrin glucosidase (maltotriose)
TCA3Sabc
Taurocholic acid 3-sulfate ABC bile acid transporter
RE3491C
Leukotriene-A4 Hydrolase
HMR_0359
HMR 0359
APOCF
Apocarboxylase formation
ASPHISPROr
Metabolism (Formation/Degradation) of AspHisPro
CYSCYSr
Metabolism (Formation/Degradation) of CysCys
STACMPtev
Efflux of sulphate-thiomethyl-acetaminophen conjugate into hepatic vein
FAH2
Fatty acid omega-hydroxylase
HMR_2376
HMR 2376
HMR_0435
HMR 0435
CE1297t
Active Transport of 8-Dehydrocholesterol
6MELVACtbc
Release of 6-exomethylene-lovastatin-acid form into bile
DCYTD
Deoxycytidine deaminase
ETHP
Ethanolamine phosphate phosphatase
THRARGTYRr
Metabolism (Formation/Degradation) of ThrArgtyr
HMR_1991
Steroid, Hydrogen-Donor:Oxygen Oxidoreductase (17-Alpha-Hydroxylating)
ARGPROMETr
Metabolism (Formation/Degradation) of ArgProMet
HMR_0469
HMR 0469
GLUTRPALAr
Metabolism (Formation/Degradation) of GluTrpAla
SERCYSARGr
Metabolism (Formation/Degradation) of SerCysArg
GLYTYRLYSr
Metabolism (Formation/Degradation) of GlytyrLys
PNTEH
Hydrolase Class RXN R02973
RE3041C
Arachidonate 5-Lipoxygenase
GLUTHRr
Metabolism (Formation/Degradation) of GluThr
DNADDP
Deamino-NAD+ nucleotidohydrolase
FUM
Fumarase
HMR_2380
HMR 2380
HMR_0298
Palmitoyl Coenzyme A Hydrolase
ALLOPOXDhep
Oxidation of allopurinol to oxypurinol in hepatocytes
RE3012C
Aldehyde Dehydrogenase (NAD+)
GMPS2
GMP synthase
RE3289C
Unspecific Monooxygenase
3HPVSteb
Efflux of 3-S-hydroxy-pravastatin into bile
GTACMPtev
Efflux of glucuronide-thiomethyl-acetaminophen conjugate into hepatic vein
HMR_1944
Steroid 17Alpha-Monooxygenase
HMR_2585
Prostaglandin-Endoperoxide Synthase
DHGLZABCt
Excretion of dehydro-gliclazide into bile
PCHOLN2254_HSABCt
Transport of 1-Docosapentenoylglycerophosphocholine (Delta 4, 7, 10, 13, 16), Sn1-Lpc (22:5)-W6
7DHCHSTEROLt
Transport of Cholesta-5, 7-Dien-3Beta-Ol, Active Transport
PGPP_hs
Phosphatidylglycerol phosphate phosphatase (homo sapiens)
FOLt2_1
Folate Transport via Anion Antiport
ALAGLYLYSr
Metabolism (Formation/Degradation) of AlaGlyLys
MERACMPtep
Efflux of acetaminophen-mercapturate-conjugate from enterocytes into portal blood
HMR_2542
Very-Long-Chain (3R)-3-Hydroxyacyl Coenzyme A Dehydratase
LYSTYRILEr
Metabolism (Formation/Degradation) of LystyrIle
PEDH203_HSPLA2
Formation of 1-Dihomo-Linolenoylglycerophosphoethanolamine (20:3, Delta 8, 11, 14) by Phospholipase A2
CHLP
Choline phosphate phosphatase
RE3287C
Unspecific Monooxygenase
HMR_0273
HMR 0273
TYRDHINDOX
Tyrosinase: 5, 6-Dihydroxyindole Oxygen Oxidoreductase
RE3180C
RE3180C
11DOCRTSTRNte
Transport of 11-Deoxycorticosterone, Extracellular
RE2675C_1
RE2675C
HMR_0394
Palmitoyl Coenzyme A Hydrolase
DOPA3GLCURt
Dopamine 3-O-Glucuronide Transport
HMR_2088
Peroxidase
HMR_0215
HMR 0215
ARGTYRVALr
Metabolism (Formation/Degradation) of ArgtyrVal
IBUP_SACOT2
Hydrolysis of ibuprofen-CoA in hepatocytes
HMR_2363
Very-Long-Chain (3R)-3-Hydroxyacyl Coenzyme A Dehydratase
HMR_0960
Glutathione Peroxidase
5OHHEXAc
Formation of 5-Hydroxy-Hexanoate
PEAR_HSPLA2
Formation of 1-Arachidonoyl-Sn-Glycero-3-Phosphoethanolamine by Phospholipase A2
TYRARGSERr
Metabolism (Formation/Degradation) of TyrArgSer
HMR_6549
1-Phosphatidyl-1D-Myo-Inositol-3, 4-Bisphosphate 4-Phosphohydrolase
PCHOLDOC_HSABCt
Transport of 1-Docosahexaenoylglycerophosphocholine
r1530
ATP-binding Cassette (ABC) TCDB:3.A.1.208.15
TYRGLUr
Metabolism (Formation/Degradation) of TyrGlu
PROCYSr
Metabolism (Formation/Degradation) of ProCys
TCDCA3Sabc
Taurochenodeoxycholic acid 3-sulfate ABC bile acid transporter
PCHOLHEP_HSPLA2
Formation of 1-Heptadecanoylglycerophosphocholine by Phospholipase A2
GLYPROPRO1c
Hydrolysis of Prolylglycine in the small intestine for cellular uptake
6CSMVACIDteb
Efflux of 6-beta-carboxy-simvastatin-acid form into bile
QUILSYN
Quinolinate Synthase Eukaryotic
RE3237C
RE3237
RE0549C
RE0549
ARTCOAL1_cho
R group coenzyme a ligase
CHSTEROLt
Cholesterol efflux (ATP depedent)
HMR_0427
HMR 0427
7KILTCHOLATP
Transport of 7-Ketolithocholate, Active Transport
11DOCRTSLte
Transport of 11-Deoxycortisol, Extracellular
HMR_0386
Palmitoyl Coenzyme A Hydrolase
PPA
Inorganic diphosphatase
TCHOLABCtc
Bile Acid Transport by ABCa8
CTPS2
CTP synthase (glutamine)
IDHPOXOX3
Iodide:hydrogen-peroxide oxidoreductase 3
ASNASNARGr
Metabolism (Formation/Degradation) of AsnAsnArg
MI14P4P
Inositol-1,4-bisphosphate 4-phosphatase
VALTRPPHEr
Metabolism (Formation/Degradation) of ValTrpPhe
TYRCYSGLYr
Metabolism (Formation/Degradation) of TyrCysGly
STCOATxc
Transport of Stearoyl-CoA from cytosol to peroxisomes
METMETILEr
Metabolism (Formation/Degradation) of MetMetIle
MI13PP
Inositol-1,3-bisphosphate 3-phosphatase
PEDH15_HSPLA2
Formation of 1-Pentadecanoylglycerophosphoethanolamine (C15:0 Pe) by Phospholipase A2
HMR_1767
7Alpha-Hydroxycholest-4-En-3-One 12Alpha-Hydroxylase
DELACCRVSM23hc
De-lactonization of cerivastatin-M31 to cerivastatin-M23 in hepatocytes
PI45PLC
Phosphatidylinositol 4,5-bisphosphate phospholipase C
LEUKTRB4WCOOHt
Transport of W-Carboxy Leukotriene B4, Active Transport
HMR_0235
HMR 0235
RE3238C
RE3238
r1162
Active transport
RE1925C
RE1925
IMPD
IMP dehydrogenase
AM1C9CSteb
Efflux of AM1c9-cyclosporine into bile
AADSACYCL
AAPSAS
HMR_8582
Alpha-Amylase
PE161_HSABCt
Transport of 1-Hexadecenoylglycerophosphoethanolamine (C16:1 Pe, Delta 9)
GLUILELYSr
Metabolism (Formation/Degradation) of GluIleLys
KAS8
B-ketoacyl synthetase (palmitate, n-C16:0)
RE1587C
Quinine 3-Monooxygenase
DHCHOLESTANATEATP
Transport of 3Alpha, 7Alpha-Dihydroxy-5Beta-Cholestanate, Active Transport
ACTLMO
Acetol monooxygenase
HMR_2289
Stearoyl Coenzyme A 9-Desaturase
RE3113C
RE3113
RE3435C
Leukotriene-B4 20-Monooxygenase
SPHMYLN18117_hs_ATPt
Transport of Sphingomyelin (D18:1/17:0), Active
3HLVSTAChep
Conversion of 3-hydroxy-lovastatin lactone to acid form
GLUVESSEC
L-glutamate secretion via secretory vesicle (ATP driven)
HMR_0954
HMR 0954
HMR_0821
Beta-N-Acetylhexosaminidase
KYN
Kynureninase
HMR_6786
4-Hydroxybenzoyl Coenzyme A Hydrolase
HMR_1549
Methylsterol Monooxygenase
CRVSATPtu
Efflux of cerivastatin by P-gp or BCRP from the enterocytes into lumen
GLUARGLEUr
Metabolism (Formation/Degradation) of GluArgLeu
NTD6
5'-nucleotidase (dAMP)
HMR_1490
Methylsterol Monooxygenase
HMR_0243
HMR 0243
PROTRPTHRr
Metabolism (Formation/Degradation) of ProTrpThr
RE3630C
RE3630C
TREH
Alpha,alpha-trehalase
THRPHEARGr
Metabolism (Formation/Degradation) of ThrPheArg
TRPARGALAr
Metabolism (Formation/Degradation) of TrpArgAla
CSAtu
Efflux of cyclosporine by P-gp from the enterocytes into lumen
HMR_2029
Unspecific Monooxygenase
RE2649C
Palmitoyl Coenzyme A Hydrolase
LCADi
Lactaldehyde dehydrogenase
ACMPGLUtep
Efflux of acetaminophen-glucuronide-conjugate from enterocytes into portal blood
IZPN
Imidazolonepropionase
3DHDCAabc
3-dehydro-deoxycholic acid ABC bile acid transporter
HMR_0211
HMR 0211
C05301te
Transport of 2-Hydroxyestradiol-17Beta, Extracellular
PLA2_2
Phospholipase A2
HMR_0325
HMR 0325
FAOXOHMC10DC10c
Fatty acid omega oxidation(w-OHMC10-->DC10)c
PHEMEABCte
Heme Transport by ABCg2
SPHMYLN181161_hs_ATPt
Transport of Sphingomyelin (D18:1/16:1), Active Transport
LYSGLUGLUr
Metabolism (Formation/Degradation) of LysGluGlu
HMR_1834
Glycodeoxycholate Amidohydrolase
SPHS1Pt2e
Export Mediated by ATP Binding Cassette (ABC) Transporters
HMR_4079
Aldehyde Dehydrogenase (NAD+)
PCHOLN24_HSPLA2
Formation of 1-Lignocericylglycerophosphocholine (24:0), Lysopc A C24 by Phospholipase A2
RE3239C
RE3239
PHELYSPROr
Metabolism (Formation/Degradation) of PheLysPro
HMR_0438
Palmitoyl Coenzyme A Hydrolase
CRVSM23teb
Efflux of cerivastatin-M23 into bile
LTHSTRLOR
Lathosterol, NADPH:oxygen 5-oxidoreductase
HMR_1477
Sterol 14Alpha-Demethylase
GLYALDDr
D-Glyceraldehyde dehydrogenase
PCHOLN224_HSABCt
Transport of 1-Docosatetraenoylglycerophosphocholine (Delta 7, 10, 13, 16), Sn1-Lpc (22:4)
PROPROPROr
Metabolism (Formation/Degradation) of ProProPro
HISTAVESSEC_1
Histamine Secretion via Secretory Vesicle (ATP Driven)
HMR_0347
HMR 0347
RETH2
Retinyl ester hydrolase (11-cis)
Pe13_HSABCt
Transport of 1-Tridecanoylglycerophosphoethanolamine (C13:0 Pe)
RE3423C
RE3423
TRPTHRGLUr
Metabolism (Formation/Degradation) of TrpThrGlu
HMR_0207
HMR 0207
TYRALAr
Metabolism (Formation/Degradation) of TyrAla
RE1978C
RE1978
HMR_0280
Palmitoyl Coenzyme A Hydrolase
LEUSERTRPr
Metabolism (Formation/Degradation) of LeuSerTrp
BTNt3i_1
Biotin Transport via Sodium Symport
PE17_HSABCt
Transport of 1-Heptadecanoylglycerophosphoethanolamine (C17:0 Pe)
IBUP_Stbc
Biliary excretion of ibuprofen from hepatocytes
XOL7AONEATP
Transport of 7Alpha-Hydroxycholest-4-En-3-One, Active Transport
THBPT4ACAMDASE
Tetrahydrobiopterin-4a-carbinolamine dehydratase
THRSERARGr
Metabolism (Formation/Degradation) of ThrSerArg
ANDRSTANDRtr
Transport of 5Alpha-Androstane-3, 17-Dione, Endoplasmatic Reticulum
PELINL_HSABCt
Transport of 1-Linoleoylglycerophosphoethanolamine (Delta 9, 12)
SMOX
Spermine oxidase
FACOAE180
Fatty-acid-CoA thioesterase (octadecanoate)
THMATPe
Thiamine exit from the neterocytes
RE3235C
RE3235
1MNCAMti
N1-Methylnicotinamide transport
SERTRPHISr
Metabolism (Formation/Degradation) of SerTrpHis
UPPN
B-ureidopropionase
ILEGLYARGr
Metabolism (Formation/Degradation) of IleGlyArg
HMR_0193
Palmitoyl Coenzyme A Hydrolase
C03990ATP
Transport of Lithocholate, Active Transport
C14825ATP
Transport of 9 (10)-Epome, Active Transport
r0641
(5-Glutamyl)-peptide:amino-acid 5-glutamyltransferase Arachidonic acid metabolism EC:2.3.2.2
EIC21114TRc
Hydrolysis of Trans, Cis, Cis-2, 11, 14-Eicosatrienoyl Coenzyme A to Trans, Cis, Cis-2, 11, 14-Eicosatrienoic Acid
CRGLZABCt
Excretion of carboxy-gliclazide into bile
HMR_1765
25/26-Hydroxycholesterol 7Alpha-Hydroxylase
ANDRSTRNGLCte
Glucuronidated compound transport
HMR_1494
Methylsterol Monooxygenase
CE7085te
Transport (ATP-Dependent) into Extracellular Space
ABUTD
Aminobutyraldehyde dehydrogenase
RNDR2
Ribonucleoside-diphosphate reductase (GDP)
C03681te
Transport of 5Alpha-Pregnane-3, 20-Dione, Extracellular
RNTR3
Ribonucleoside triphosphate reductase CTP
RE3258C
Microsomal Epoxide Hydrolase
GLDBRAN
Glycogen debranching enzyme
3HSMVACIDhep
Conversion of 3-hydroxy simvastatin lactone to acid form
HMR_1536
Sterol 14Alpha-Demethylase
ESTRIOLGLCte
Glucuronidated compound transport
METGLYARGr
Metabolism (Formation/Degradation) of MetGlyArg
HMR_0946
Unspecific Monooxygenase
PCHOL2STE_HSABCt
Transport of 2-Stearoylglycerophosphocholine
SMVACIDATPteb
Efflux of simvastatin dihydroxy acid form into bile
r1521
ATP-binding Cassette (ABC) TCDB:3.A.1.211.1
RE1919C
RE1919
NADN
NAD nucleosidase
ALDD2x
Aldehyde dehydrogenase (acetaldehyde, NAD)
FAS140COA
Fatty acyl CoA synthase n C140CoA
AM1A4NCSteb
Efflux of AM1A4N-cyclosporine into bile
HMR_0328
Palmitoyl Coenzyme A Hydrolase
41R1H2MAE12BOOX
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol:oxygen oxidoreductase(deaminating)(flavin-containing)
r1514
ATP-binding Cassette (ABC) TCDB:3.A.1.211.1
DESAT14_9
Desaturation of Myristic Acid to 9-Tetradecenoic Acid
GLYLYSPHEr
Metabolism (Formation/Degradation) of GlyLysPhe
RE2349C
Kynurenine-Oxoglutarate Transaminase
TRPALAPROr
Metabolism (Formation/Degradation) of TrpAlaPro
ARGPROTHRr
Metabolism (Formation/Degradation) of ArgProThr
CE7090te
Transport (ATP-Dependent) into Extracellular Space
34DHPLACOX_NADP
34DHPLACOX LPAREN NADP RPAREN
HMR_1504
Methylsterol Monooxygenase
HMR_1478
Sterol 14Alpha-Demethylase
DOCO13ECOAtxc
Transport of 13-Docosenoylcoa into Peroxisomes
FACOAE1839Z12Z15Z
Alpha-Linolenoyl-CoA hydrolase (18:3(9Z,12Z,15Z))
FldAct
Fldact
CE1243ATP
Transport of 12S-HHT, FATP
ASNS1
Asparagine synthase (glutamine-hydrolysing)
HMR_1318
HMR 1318
PCHOLN201_HSABCt
Transport of 1-Eicosenoylglycerophosphocholine (Delta 11) , Sn1-Lpc (20:1)
CSASULPteb
Efflux of cyclosporine-sulphate into bile
THRMETARGr
Metabolism (Formation/Degradation) of ThrMetArg
PROLYSPROr
Metabolism (Formation/Degradation) of ProLysPro
PHEASPr
Metabolism (Formation/Degradation) of PheAsp
CE2049te
Transport (ATP-Dependent) into Extracellular Space
RSVLACteb
Efflux of rosuvastatin-5S-lactone into bile
HISGLUr
Metabolism (Formation/Degradation) of HisGlu
GPDDA1
Glycerophosphodiester phosphodiesterase (Glycerophosphocholine)
r1529
ATP-binding Cassette (ABC) TCDB:3.A.1.211.1
RE3040C
Microsomal Epoxide Hydrolase
P4503A5
Cytochrome P450 3A5
r1520
ATP-binding Cassette (ABC) TCDB:3.A.1.211.1
AM19CSteb
Efflux of AM19-cyclosporine into bile
HMR_0321
HMR 0321
HMR_0272
Palmitoyl Coenzyme A Hydrolase
MHGLZABCt
Excretion of Methyl-hydroxy-gliclazide into bile
NOS1
L-Arginine,NADPH:oxygen oxidoreductase (N-(omega)-hydroxyarginine-forming)
ILESERARGr
Metabolism (Formation/Degradation) of IleSerArg
ASPLYSHISr
Metabolism (Formation/Degradation) of AspLysHis
ARGLYSASPr
Metabolism (Formation/Degradation) of ArgLysAsp
PROFVShc
Thioesterase/ hydrolase for release of des-isoproylpropionic-acid-fluvastatin in hepatocytes
RE3220C
Steryl-Sulfatase
DESAT18_11
Stearoyl Coenzyme A Desaturase (N-C18:0CoA -> N-C18:1CoA)
CYSGLUTRPr
Metabolism (Formation/Degradation) of CysGluTrp
7BHGLZABCt
Excretion of 7-beta-OH-gliclazide into bile
ACODA
Acetylornithine deacetylase
HMR_0597
Phosphatidate Phosphatase
42A12BOOX
4-(2-Aminoethyl)-1,2-benzenediol:oxygen oxidoreductase(deaminating)(flavin-containing)
GLNLYSTRPr
Metabolism (Formation/Degradation) of GlnLysTrp
r0193
L-Cysteine L-homocysteine-lyase (deaminating) Cysteine metabolism EC:4.4.1.1
PCHOLN225_HSABCt
Transport of 1-Docosapentenoylglycerophosphocholine (Delta 7, 10, 13, 16, 19), Sn1-Lpc (22:5)-W3
PCHOLN225_HSPLA2
Formation of 1-Docosapentenoylglycerophosphocholine (Delta 7, 10, 13, 16, 19), Sn1-Lpc (22:5)-W3 by Phospholipase A2
r0210
L-Serine hydro-lyase (adding homocysteine) Glycine, serine and threonine metabolism EC:4.2.1.22
LPASE
Lysophospholipase
TRIPVSteb
Efflux of triol metabolite of pravastatin into bile
LEUTRPr
Metabolism (Formation/Degradation) of LeuTrp
TRPGLUPROr
Metabolism (Formation/Degradation) of TrpGluPro
CE4877te
Transport (ATP-Dependent) into Extracellular Space
DKMPPD3_1
Acireductone Synthase (Homo Sapiens)
PROPROARGr
Metabolism (Formation/Degradation) of ProProArg
PCHOLN1836_HSABCt
Transport of 1-Octadeca-Trienoylglycerophosphocholine, Sn1-Lpc (18:3, Delta 6, 9, 12)
LCA24Gte
Glucuronidated bile acid excretion (LCA-24G)
BETALDHx
Betaine-aldehyde dehydrogenase
r2497
ATP-binding Cassette (ABC) TCDB:3.A.1.203.3
NRVNCABCt
Transport of 15-Tetracosenoate, Diffusion
GUDCA3Sabc
Glycoursodeoxycholic acid 3-sulfate ABC bile acid transporter
TRPMETVALr
Metabolism (Formation/Degradation) of TrpMetVal
GLACO
D-Glucuronolactone:NAD+ oxidoreductase
HMR_0828
Beta-N-Acetylhexosaminidase
PSHSABCtc
Phosphatidylserine Transport by ABCa1
RE3228C
RE3228
RE2439C
RE2439
RE0575C
RE0575
ARGVALCYSr
Metabolism (Formation/Degradation) of ArgValCys
3DHCDCHOLabc
3-Dehydrochenodeoxycholic acid ABC bile acid transporter
41R2A1H12BOOX
4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol:oxygen oxidoreductase(deaminating)(flavin-containing)
PRFGS
Phosphoribosylformylglycinamidine synthase
HMR_2535
Very-Long-Chain (3R)-3-Hydroxyacyl Coenzyme A Dehydratase
GLUPRT
Glutamine phosphoribosyldiphosphate amidotransferase
SPHMYLN18114_hs_ATPt
Transport of Sphingomyelin (D18:1/14:0), Active Transport
RE3163C
RE3163
HMR_1847
Steryl-Sulfatase
VALLYSTYRr
Metabolism (Formation/Degradation) of ValLystyr
NTD8
5'-nucleotidase (dGMP)
RE3038C
Microsomal Epoxide Hydrolase
PE2LINL_HSABCt
Transport of 2-Linoleoylglycerophosphoethanolamine
URCN
Urocanase
VALVALr
Metabolism (Formation/Degradation) of ValVal
EPOXTACteb
Efflux of 31-O-Desmethyl,19-Hydroxy,37, 39-Epoxy-tacrolimus into bile
CE6247t
Transport of 5, 12, 20-Trihete, Active Transport
ACYP
Acylphosphatase
PPA2
Inorganic triphosphatase
CA24Gte
Glucuronidated bile acid excretion (CA-24G)
TACRtu
Efflux of tacrolimus into intestinal lumen by P-gp
METOX
L-Methionine oxidase
ARGDr
Arginine deiminase
ATVACIDhc
Conversion of lactone to acid form of atorvastatin in hepatocytes
THRTHRARGr
Metabolism (Formation/Degradation) of ThrThrArg
r1528
ATP-binding Cassette (ABC) TCDB:3.A.1.211.1
HC02194te
Transport of Bile Acid, Ursodeoxycholate, Active Transport
CPPPGO
Coproporphyrinogen oxidase (O2 required)
PHEPHETHRr
Metabolism (Formation/Degradation) of PhePheThr
CHSTEROLtg
Cholesterol efflux (ATP depedent), golgi
HMR_1548
Methylsterol Monooxygenase
ASPGLUr
Metabolism (Formation/Degradation) of AspGlu
AM1CGLCteb
Efflux of AM1c-glucuronide into bile
SERHL
L-Serine hydro-lyase
SBPP1
Sphinganine 1-phosphate phosphatase
PCHOLN183_HSABCt
Transport of 1-Octadeca-Trienoylglycerophosphocholine, Sn1-Lpc (18:3, Delta 9, 12, 15)
PNTOt5
Pantothenate sodium symporter II
PROSTGE1t3
Prostaglandine E1 transport (ATP-dependent)
GABAVESSEC_1
GABA Secretion via Secretory Vesicle (ATP Driven)
IDHPOXOX4
Iodide:hydrogen-peroxide oxidoreductase 4
FAEL205
Fatty-acyl-CoA elongation (n-C20:5CoA)
ASPASNGLUr
Metabolism (Formation/Degradation) of AspAsnGlu
TSTSTERONEGLCte
Glucuronidated compound transport
CDCA6AH
Chenodeoxycholic acid 6alpha-hydroxylase
NMNDA
Nicotinamide-nucleotide amidase
6EPSteb
Efflux of 6-epipravastatin into bile
C04805ATP
Transport of 5(S)-HETE, Active Transport
HMR_0366
Palmitoyl Coenzyme A Hydrolase
FVSteb
Efflux of fluvastatin into bile for excretion into faeces
PEDH14_HSPLA2
Formation of 1-Myristoylglycerophosphoethanolamine (C14:0 Pe) by Phospholipase A2
7HPVSteb
Efflux of 7-hydroxy-3-alpha-iso-pravastatin into bile
NOS2_2
Nitric Oxide Synthase (No Forming)
GDCA3Sabc
Glycodeoxycholic acid 3-sulfate ABC bile acid transporter
CYSTYRASNr
Metabolism (Formation/Degradation) of CystyrAsn
PI4PP
Phosphatidylinositol-4-phosphate 4-phosphatase
CYSTGL
Cystathionine g lyase
DHPM1
Dihydropyrimidinase (5,6-dihydrouracil)
AHANDROSTANtr
Transport of 3Alpha-Hydroxy-5Beta-Androstan-17-One, Endoplasmatic Reticulum
BIOMASS_maintenance_noTrTr
Biomass maintenance reaction without replication, transcription, and translation precursors
4HATVLACteb
Efflux of 4-hydroxy-atorvastatin-lactone into bile
PE14_HSABCt
Transport of 1-Myristoylglycerophosphoethanolamine (C14:0 Pe)
HYPOE
Hypothetical enyme
HISHISLYSr
Metabolism (Formation/Degradation) of HisHisLys
GLNTRPGLUr
Metabolism (Formation/Degradation) of GlnTrpGlu
r2517
ATP-binding Cassette (ABC) TCDB:3.A.1.203.1
3HSMVACIDteb
Efflux of 3-hydroxy-simvastatin-acid form into bile
PROHISr
Metabolism (Formation/Degradation) of ProHis
RE3288C
Unspecific Monooxygenase
CHTNASE
CHTNASE
HMR_1543
Methylsterol Monooxygenase
DOCOSCOAtxc
Transport of behenoylcoa into peroxisomes
METHISLYSr
Metabolism (Formation/Degradation) of MetHisLys
HMR_0210
Palmitoyl Coenzyme A Hydrolase
GLNASNGLNr
Metabolism (Formation/Degradation) of GlnAsnGln
PCHOLN19_HSPLA2
Formation of 1-NoNADecanoylglycerophosphocholine, Sn1-Lpc (19:0) by Phospholipase A2
G5SADs
L-glutamate 5-semialdehyde dehydratase (spontaneous)
1331TACRteb
Efflux of 13,31-O-Didesmethyl-tacrolimus into bile
HMR_2293
Stearoyl Coenzyme A 9-Desaturase
ILEARGILEr
Metabolism (Formation/Degradation) of IleArgIle
HMR_7756
2-Phenylacetamide Amidohydrolase
ACChex
Palmitoyl Coenzyme A Hydrolase
HMR_0414
Palmitoyl Coenzyme A Hydrolase
PE12_HSABCt
Transport of 1-Didecanoylglycerophosphoethanolamine (C12:0 Pe)
GPDDACHOL
Glycerophosphocholine Phosphodiesterase
THYOCHOLabc
Taurohyocholic acid ABC bile acid transporter
CLOHtex2_1
Chloride Transport via Hydroxide Antiport (2:1)
DESAT18_8
Fatty acyl-CoA desaturase (n-C18:1CoA -> n-C18:2CoA)
GLYHISASNr
Metabolism (Formation/Degradation) of GlyHisAsn
HMR_6611
Urate:Oxygen Oxidoreductase
TYROX
L-Tyrosine oxidase
RE2675C2
Re2675C2
RE1933C
Arylesterase
CAMPt
CAMP transport (ATP-dependent)
RE3013C
Unspecific Monooxygenase
GLCSGLT1le
Transport of D-glucose from extracellular space to cytosol of mucosal cells in small intestine
MAOLNOR
Monoamine oxidase (L-Normetanephrine)
SCP21cx
Transport of phytanoylcoa from cytosol to peroxisomes.
THRS
Threonine synthase
HMR_0374
Palmitoyl Coenzyme A Hydrolase
HMR_2269
Very-Long-Chain (3R)-3-Hydroxyacyl Coenzyme A Dehydratase
HMR_0847
Exo-Alpha-Sialidase
BTNt3i
Biotin transport via sodium symport
HMR_1737
24-Hydroxycholesterol 7Alpha-Hydroxylase
PAILPALM_HSPLA2
Formation of 1-Palmitoylglycerophosphoinositol by Phospholipase A2
BTND1
Biotinidase (biotin)
DCA24Gte
Glucuronidated bile acid excretion (DCA-24g)
HMR_8643
Carboxylesterase
HOXG
Heme oxygenase 1
RE2240C
RE2240
PROSTGE2t3
Prostaglandine E2 transport (ATP-dependent)
P4502D6
Cytochrome P450 2D6
HMR_1993
Progesterone, Reduced Ferredoxin:Oxygen Oxidoreductase (11-Hydroxylating)
RETABCtc
Vitamin Transport by ABCa4
ICDCHOLabc
Isochenodeoxycholic acid ABC bile acid transporter
GTHRDt
Glutathione transport into mitochondria
C05770te
Transport by Atb Binding Cassette Transporter ABCc2 into Extracellular Space
CBL2OR
NADH:cob(III)alamine oxidoreductase
CYSGLNMETr
Metabolism (Formation/Degradation) of CysGlnMet
HYOCHOLabc
Hyocholic acid ABC bile acid transporter
12HPETATP
Transport of 12-Hydroperoxyeicosa-5, 8, 10, 14-Tetraenoate, by FATP
UDPG1P
UDPglucuronate uridine-monophosphohydrolase
PPPGO
Protoporphyrinogen oxidase (aerobic)
18HARACHDte
Transport of 18 Hydroxy Arachidonic Acid, Extracellular Space, Active Transport
RE3381C
Beta-Glucuronidase
NRPPHRVESSEC_1
Secretion of Noradrenaline via Secretory Vesicle (ATP Driven)
IBUP_SCYPCARhep
Oxidation of S-3-hydroxy ibuprofen to S-carboxy ibuprofen
r0795
Spontaneous reaction
RE0691C
RE0691
HMR_0811
Alpha-N-Acetylgalactosaminidase
RSVSPONhc
Conversion of lactone to open acid form of rosuvastatin
CE2211te
Transport of Allopregnanolone, Extracellular
r0085
2-Oxoglutaramate amidohydrolase Glutamate metabolism EC:3.5.1.3
HMR_0825
Exo-Alpha-Sialidase
HMR_4702
HMR 4702
HMR_0370
Palmitoyl Coenzyme A Hydrolase
4GLU56DIHDINDt
Transport of 4-S-Glutathionyl-5, 6-Dihydroxyindoline
DESAT18_5
Stearoyl-CoA desaturase (n-C18:0CoA -> n-C18:1CoA)
MI1PP
Myo-inositol 1-phosphatase
ARGGLUGLUr
Metabolism (Formation/Degradation) of ArgGluGlu
PNTOt5_1
Pantothenate Sodium Symporter Ii
HMR_0672
Triacylglycerol Lipase
TRPGLUGLYr
Metabolism (Formation/Degradation) of TrpGluGly
FACOAE161
Fatty-acid-CoA thioesterase (hexadecenoate)
17AHPRGSTRNte
Transport of 17Alpha-Hydroxyprogesterone, Extracellular
HC02196te
Transport of Bile Acid, Glycoursodeoxycholate, Active Transport
HMR_0246
Palmitoyl Coenzyme A Hydrolase
RE2080C
RE2080
RE0916C
Steryl-Sulfatase
HMR_0383
HMR 0383
RE1233C
Kynurenine-Oxoglutarate Transaminase
HC02220te
Transport of Bile Acid, Sulfochenodeoxycholate, Active Transport
RETH1
Retinyl ester hydrolase (9-cis)
HMR_2560
HMR 2560
MITKP
D-myo-Inositol 1,3,4,5-tetrakisphosphate 3-phosphohydrolase
3MOX4HOXPGALDOX_NADP
3-Methoxy-4-hydroxyphenylglycolaldehyde:NADP+ oxidoreductase
SPHMYLN18123_hs_ATPt
Transport of Sphingomyelin (D18:1/23:0), Active
RE3095C
Peroxidase
PI4PLC
Phosphatidylinositol 4-phosphate phospholipase C
TUDCA3Sabc
Tauroursodeoxycholic acid 3-sulfate ABC bile acid transporter
LEUKABCtc
Leukotriene Transport by ABCa8
RE0571C
RE0571
HMR_0324
Palmitoyl Coenzyme A Hydrolase
HMR_0426
Palmitoyl Coenzyme A Hydrolase
UPP3S
Uroporphyrinogen-III synthase
RE0577C
Palmitoyl Coenzyme A Hydrolase
LYSVALPHEr
Metabolism (Formation/Degradation) of LysValPhe
CE0328t
Transport of Docosahexaenoate
AM1C4N9CSteb
Efflux of AM1c4N9-cyclosporine into bile
12DHCHOLabc
12-Dehydrocholic acid ABC bile acid transporter
CRVSM1SPhc
De-lactonization of cerivastatin-M22 to cerivastatin-M1 in hepatocytes
PE224_HSPLA2
Formation of 1-Docosatetraenoyglycerophosphoethanolamine (22:4, Delta 7, 10, 13, 16) by Phospholipase A2
r0466_1
Alpha-Aminobutyryl Histidine Hydrolase
HMR_0302
Palmitoyl Coenzyme A Hydrolase
LYSLYSLYSr
Metabolism (Formation/Degradation) of LysLysLys
TRPTHRILEr
Metabolism (Formation/Degradation) of TrpThrIle
TYRLEUARGr
Metabolism (Formation/Degradation) of TyrLeuArg
ASPVALASNr
Metabolism (Formation/Degradation) of AspValAsn
5FTHFt2_1
5-Formyltetrahydrofolate Transport via Anion Exchange
DESAT18_12
Fatty Acyl Coenzyme A Desaturase (N-C18:1CoA -> N-C18:2CoA)
GUR1PP
Glucuronate 1-phosphate phosphatase
STS4
Steryl-sulfatase
PE203_HSABCt
1-Eicosatrienoylglycerophosphoethanolamine (Delta 11, 14, 17), Lpe (20:3)
HMR_2359
HMR 2359
TRPILETRPr
Metabolism (Formation/Degradation) of TrpIleTrp
PELPALM_HSABCt
Transport of 1-Palmitoylglycerophosphoethanolamine
HEXDIACATP
Transport of Hexadecanediocacid by FATP
GLUASNLEUr
Metabolism (Formation/Degradation) of GluAsnLeu
ATVACIDtu
Efflux of atorvastatin acid by P-gp from the enterocytes into lumen
RE2640C
N-Acyl-Aliphatic-L-Amino Acid Amidohydrolase
PCHOLN224_HSPLA2
Formation of 1-Docosatetraenoylglycerophosphocholine (Delta 7, 10, 13, 16), Sn1-Lpc (22:4) by Phospholipase A2
C14769td2
Transport of 8, 9-EET, Active Transport
MI4PP
1D-myo-Inositol 4-phosphate phosphohydrolase
HMR_0247
HMR 0247
RADH4
Retinal dehydrogenase (NADPH)
G6PDA
Glucosamine-6-phosphate deaminase
MDZtu
Efflux of midazolam by P-gp from the enterocytes into lumen
HMR_6550
Phosphatidylinositol-3, 4, 5-Trisphosphate 3-Phosphatase
r2503
ATP-binding Cassette (ABC) TCDB:3.A.1.203.3
HMR_7628
L-Phenylalanine:Oxygen Oxidoreductase (Decarboxylating)
HMR_1544
Methylsterol Monooxygenase
PCHOL2OLE_HSPLA2
Formation of 2-Oleoylglycerophosphocholine by Phospholipase A2
HMR_8576
Alpha-Amylase
ALDD21
Aldehyde dehydrogenase (pristanal, NAD)
LVSTACIDhep
Conversion of pro-durg lovastatin to active hydroxyacid form in hepatocytes
CGMPt
CGMP transport (ATP-dependent)
PCHOLDOC_HSPLA2
Formation of 1-Docosahexaenoylglycerophosphocholine by Phospholipase A2
PTVSTM3eb
Efflux of pitavastatin-M3 into bile
ARGVALTRPr
Metabolism (Formation/Degradation) of ArgValTrp
NRVNCCOAtxc
Transport of nervonylcoa into peroxisomes
2HATVLACteb
Efflux of 2-hydroxy-atorvastatin-lactone into bile
RE3490C
RE3490
HISLYSGLUr
Metabolism (Formation/Degradation) of HisLysGlu
MI3PP
1D-myo-Inositol 3-phosphate phosphohydrolase
HMR_2336
Very-Long-Chain (3R)-3-Hydroxyacyl Coenzyme A Dehydratase
r0239
N-Formylanthranilate amidohydrolase Tryptophan metabolism EC:3.5.1.9
HMR_0329
HMR 0329
4BHGLZABCt
Excretion of 4-beta-OH-gliclazide into bile
ACP1_FMN
Acid phosphatase (FMN)
TCDCA6AH
Taurochenodeoxycholic acid 6alpha-hydroxylase
NaKt_1
Na+/K+ Exchanging ATPase
NTD2
5'-nucleotidase (UMP)
HISGLYLYSr
Metabolism (Formation/Degradation) of HisGlyLys
r2501
ATP-binding Cassette (ABC) TCDB:3.A.1.203.3
C04717ATP
Transport of 13(S)-HPODE, Active
HMGCOAS
Hydroxymethylglutaryl CoA synthase
RNDR1
Ribonucleoside-diphosphate reductase (ADP)
HMR_2484
HMR 2484
TYRTRPPHEr
Metabolism (Formation/Degradation) of TyrTrpPhe
r1531_1
ATP-Binding Cassette (ABC) Tcdb:3.A.1.208.15
PCHOLMYR_HsABCt
Transport of 1-Myristoylglycerophosphocholine
GGT6
Gamma-glutamyltransferase
P4503A4
Cytochrome P450 3A4
r0993
ATP-binding Cassette (ABC) TCDB:3.A.1.208.2
HMR_1321
HMR 1321
H2Otm
H2O transport mitochondrial
PHELEUHISr
Metabolism (Formation/Degradation) of PheLeuHis
LCA3Gte
Glucuronidated bile acid excretion (LCA-3G)
LEUKTRB4WOHt
Transport of W-Hydroxyl Leukotriene B4, Active Transport
KYN3OX
Kynurenine 3 monooxygenase
FAS160COA
Fatty acyl CoA synthase n C160CoA
GLYHISLYSr
Metabolism (Formation/Degradation) of GlyHisLys
PCHOLN205_HSABCt
Transport of 1-Eicosapentenoylglycerophosphocholine (Delta 5, 8, 11, 14, 17), Sn1-Lpc (20:5)
RE0579C_1
Palmitoyl Coenzyme A Hydrolase
NTD12
5'-nucleotidase (dIMP)
TRPGLYVALr
Metabolism (Formation/Degradation) of TrpGlyVal
r0511
Steroyl Coenzyme A, Hydrogen-Donor:Oxygen Oxidoreductase Polyunsaturated Fatty Acid Biosynthesis
UDPGNP
UDP-glucuronate glucuronohydrolase
NEU23
Sialidase, Cytosol (Neu2)
4HALDD
Aldehyde dehydrogenase 4 hydroxyphenylacetaldehyde NAD
r0741
5Beta-Cholestane-3Alpha, 7Alpha, 12Alpha-Triol, NADPH:Oxygen Oxidoreductase (26-Hydroxylating) Bile Acid Biosynthesis
3DHCDCAS
3-dehydro-chenodehydroxycholic acid formation
TYRDOPOX
Tyrosinase: Dopamine Oxidation
C14826ATP
Transport of 12 (13)-Epome, FATP
RE1632C
Quinine 3-Monooxygenase
TRPPROGLYr
Metabolism (Formation/Degradation) of TrpProGly
3OHACMPtev
Efflux of 3-OH-acetaminophen into hepatic vein
HMR_9807
5-Phosphonooxy-L-Lysine Phospho-Lyase
HMR_0260
Palmitoyl Coenzyme A Hydrolase
CE5026t
Transport of 5-S-Glutathionyl-L-Dopa
GLYPHEHYc
Hydrolysis of glycylphenylalanine
XOL7AH3ATP
Transport of 5Beta-Cholestane-3Alpha, 7Alpha, 26-Triol, Active Transport
FKYNH
N Formyl L kynurenine amidohydrolase
LEUPROr
Metabolism (Formation/Degradation) of LeuPro
SPHMYLN1825_hs_ATPt
Transport of Sphingomyelin (D18:0/25:0), Active Transport
SBPP3
Sphingosine 1-phosphate phosphatase
HMR_0390
Palmitoyl Coenzyme A Hydrolase
THRTYRMETr
Metabolism (Formation/Degradation) of ThrtyrMet
TYRDOPO3
Tyrosine:dopa oxidase (dopaquinone producing 2)
2HATVLACGLUCteb
Efflux of 2-hydroxy-atorvastatin-lactone-glucuronide into bile
ACOAH
Acetyl-CoA hydrolase
PCHOLN203_HSABCt
Transport of 1-Dihomo-Linolenoylglycerophosphocholine (20:3, Delta 8, 11, 14), Lysopc A C20:3
RSVATPtu
Efflux of rosuvastatin by BCRP from the enterocytes into lumen
FACOAE1836Z9Z12Z
Gamma-Linolenoyl-CoA hydrolase (18:3(6Z,9Z,12Z))
SMVHYDROhep
Conversion of simvastatin pro-drug to active form
RE0830C
4A-Hydroxytetrahydrobiopterin Dehydratase
GTHPi
Glutathione peridoxase
LVSTPGPtu
Efflux of lovastatin lactone by P-gp from the enterocytes into lumen
C14825c
Formation of 9 (10)-Epome
RE2130C
RE2130
GLUGLUr
Metabolism (Formation/Degradation) of GluGlu
DUTPDP
DUTP diphosphatase
TRPMETARGr
Metabolism (Formation/Degradation) of TrpMetArg
15HPETATP
Transport of 15(S)-HPETE, Active Transport
PCHOL2LINL_HSPLA2
Formation of 2-Linoleoylglycerophosphocholine by Phospholipase A2
RE3259C
Microsomal Epoxide Hydrolase
P4502C94
Cytochrome P450 2C9
VALPROTRPr
Metabolism (Formation/Degradation) of ValProTrp
RE3486C
RE3486
5HOXINDACTOX
5-Hydroxyindoleacetaldehyde:NAD+ oxidoreductase
DCMPDA
DCMP deaminase
r0403
L-Tryptophan, Tetrahydrobiopterin:Oxygen Oxidoreductase (5-Hydroxylating)
HMR_1958
17Alpha-Hydroxypregnenolone Acetaldehyde-Lyase
HMR_0371
HMR 0371
TYMc
Formation of Tyraminium
HEXDTRte
Transport of 7, 10, 13-Hexadecatrienoic Acid into Extracellular Space
LEUTRPARGr
Metabolism (Formation/Degradation) of LeuTrpArg
13DMTtu
Efflux of 13-O-desmethyl tacrolimus into intestinal lumen by ABC transporter
RE3252C
RE3252
PGS
Prostaglandin G/H synthase
PCHOLN15_HSPLA2
Formation of 1-Pentadecanoylglycerophosphocholine, Sn1-Lpc (15:0) by Phospholipase A2
HISLYSILEr
Metabolism (Formation/Degradation) of HisLysIle
MHISOR
N-Methylhistamine:oxygen oxidoreductase (deaminating)
GCDCA3Sabc
Glycochenodeoxycholic acid 3-sulfate ABC bile acid transporter
GCALDD
Glycolaldehyde dehydrogenase
THRGLNTYRr
Metabolism (Formation/Degradation) of ThrGlntyr
FACOAE1829Z12Z
Linoleoyl-CoA hydrolase (18:2(9Z,12Z))
HMR_2393
HMR 2393
HMR_1786
Cholesterol 25-Hydroxylase
r2499
ATP-binding Cassette (ABC) TCDB:3.A.1.203.3
PPP9ABCte
Transport by ABCg2 into Extracellular Space
DOPABMO_1
Dopamine Beta-Monooxygenase
7AHGLZABCt
Excretion of 7-alpha-OH-gliclazide into bile
SPHMYLN18121_hs_ATPt
Transport of Sphingomyelin (D18:1/21:0), Active
THMMPt4_1
Thiamine Monophosphate Transport in via Anion Antiport
HMR_2365
HMR 2365
SERARGTRPr
Metabolism (Formation/Degradation) of SerArgTrp
r1383_1
Gamma-Glutamyl Hydrolase
PHETHRLYSr
Metabolism (Formation/Degradation) of PheThrLys
C14770ATP
Transport of 11, 12-EET, FATP
HISLYSVALr
Metabolism (Formation/Degradation) of HisLysVal
INOSTO
Myo-Inositol:oxygen oxidoreductase
METAT
Methionine adenosyltransferase
HMR_0753
Ceramidase
SERLYSHISr
Metabolism (Formation/Degradation) of SerLysHis
HISPHEARGr
Metabolism (Formation/Degradation) of HisPheArg
HCO3E
HCO3 equilibration reaction
GUAD
Guanine deaminase
ACGPID
N-acetylglucosaminylphosphatidylinositol deacetylase
HMR_0375
HMR 0375
PCHOLN264_HSABCt
Transport of 1-Lignocericylglycerophosphocholine (24:0), Lysopc A C24
ASNPHECYSr
Metabolism (Formation/Degradation) of AsnPheCys
PYDXPP
Pyridoxal 5-phosphate phosphatase
PDXPP
Pyridoxine 5-phosphate phosphatase
APOC_LYS_BTNP
Proteolysis of apoC-Lys-btn
DHEASABCCte
Dhea Transport by ABCa11
FACOAE181
Fatty-acid-CoA thioesterase (octadecenoate)
r1392
Amylo-1,6-glucosidase, 4-alpha-glucanotransferase EC:3.2.1.33
PEPALM_HSPLA2
Formation of 1-Palmitoylglycerophosphoethanolamine by Phospholipase A2
FPGS_1
Folylpolyglutamate Synthetase
AK2LGCHOLABCt
1-Alkyl 2-Acylglycerol 3-Phosphocholine Transport
RE0567C
RE0567
HMR_6729
L-Tyrosine:Oxygen Oxidoreductase
HMR_0238
Palmitoyl Coenzyme A Hydrolase
METTRPPHEr
Metabolism (Formation/Degradation) of MetTrpPhe
HMR_0942
Unspecific Monooxygenase
15DMTtu
Efflux of 15-O-desmethyl tacrolimus into intestinal lumen by ABC transporter
SFGTHi
S-Formylglutathione hydralase
HISTASE
HISTASE

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Universal metabolite ?

Old identifiers

    h2o[c]

h2o in other models