BiGG Models is currently a beta release, which means that we are still
testing the database and website. Please be patient if you encounter bugs,
and be aware that some changes to the database content may change before the
final release. If you have questions or find any bugs in the database,
please contact Zachary King (zaking-AT-ucsd-DOT-edu).
BiGG is a knowledgebase of Biochemically, Genetically and Genomically
structured genome-scale metabolic network reconstructions.
BiGG integrates more than 70 published genome-scale metabolic
networks into a single database with a set of stardized identifiers
called BiGG IDs. Gene in the BiGG models are mapped to NCBI genome
annotations, and metabolites are linked to many external databases
(KEGG, PubChem, and many more).
BiGG can be browsed on this website or accessed using a web
API. Try searching for a metabolite, reaction, gene, or organism in the
search box to browse the content of genome-scale models. Question marks like
are available throughout the site to
provide more help. Further information is available in the
BiGG Models publication.
How do I cite BiGG Models?
When using the BiGG Models knowledgebase in your research, we kindly ask
that you cite the latest publication. Your citation of BiGG Models will help
us to apply for ongoing funding to maintain this resource.
King ZA, Lu JS, Dräger A, Miller PC, Federowicz S, Lerman JA, Ebrahim A,
Palsson BO, and Lewis NE. (2015). BiGG Models: A platform for
integrating, standardizing, and sharing genome-scale models.
Nucl Acids Res. doi:10.1093/nar/gkv1049.
Permission to use, copy, modify and distribute any part of BiGG Models for
educational, research and non-profit purposes, without fee, and without a
written agreement is hereby granted, provided that the above copyright
notice, this paragraph and the following three paragraphs appear in all
Those desiring to incorporate BiGG Models into commercial products or use
for commercial purposes should contact the Technology Transfer &
Intellectual Property Services, University of California, San Diego, 9500
Gilman Drive, Mail Code 0910, La Jolla, CA 92093-0910, Ph: (858) 534-5815,
FAX: (858) 534-7345, e-mail: firstname.lastname@example.org.
In no event shall the University of California be liable to any party for
direct, indirect, special, incidental, or consequential damages, including
lost profits, arising out of the use of this bigg database, even if the
University of California has been advised of the possibility of such damage.
The BiGG Models provided herein is on an "as is" basis, and the University
of California has no obligation to provide maintenance, support, updates,
enhancements, or modifications. The University of California makes no
representations and extends no warranties of any kind, either implied or
express, including, but not limited to, the implied warranties of
merchantability or fitness for a particular purpose, or that the use of the
BiGG Models will not infringe any patent, trademark or other rights.