Reaction: SMVHYDROhep

Descriptive name:

Conversion of simvastatin pro-drug to active form

Model:

Recon3D

Reaction:

h2o_c + smv_c → h_c + smvacid_c

Metabolites:

Stoichiometry
BiGG ID
Name
1.0
h_c
H+
-1.0
h2o_c
H2O H2O
1.0
smvacid_c
Simvastatin dihydroxy acid form
-1.0
smv_c
Simvastatin lactone form

Default bounds:

(0.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Drug metabolism

Gene Reaction Rule:

5446_AT1

Genes:

5446_AT1 (PON3)

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Universal reaction ?

External database links

Old identifiers

    SMVHYDROhep

SMVHYDROhep in other models