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Metabolite: smv_c


Descriptive name:

Simvastatin lactone form

Model:

Recon3D

Formula:

C25H38O5

Charge:

0

Compartment:

c - cytosol

Reactions:

BiGG ID
Name
SMVHYDROhep
Conversion of simvastatin pro-drug to active form
SMVitr
SMVitr
SMVLAChep
Conversion of open acid form to lactone form of simvastatin
SMVthep
Uptake of simvastatin by hepatocytes
SMVtu
Efflux of simvastatin by P-gp from the enterocytes into lumen
SMVtv
Uptake of simvastatin by enterocytes

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Universal metabolite ?

  • smv

External database links

Old identifiers

    smv[c]

smv in other models


Latest BiGG Models publication:

King ZA, Lu JS, Dräger A, Miller PC, Federowicz S, Lerman JA, Ebrahim A, Palsson BO, and Lewis NE. BiGG Models: A platform for integrating, standardizing, and sharing genome-scale models (2016) Nucleic Acids Research 44(D1):D515-D522. doi:10.1093/nar/gkv1049


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