Reaction: SMVtu

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Descriptive name:

Efflux of simvastatin by P-gp from the enterocytes into lumen

Model:

Recon3D

Reaction:

atp_c + h2o_c + smv_c → adp_c + h_c + pi_c + smv_e

Metabolites:

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Default bounds:

(0.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Drug metabolism

Gene Reaction Rule:

5243_AT1

Genes:

5243_AT1 (ABCB1)

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