Universal reaction: SMVtu

Descriptive name:

Efflux of simvastatin by P-gp from the enterocytes into lumen

Reaction:

atp_c + h2o_c + smv_c ⇌ adp_c + h_c + pi_c + smv_e

Metabolites:

Stoichiometry
BiGG ID
Name
1.0
adp_c
ADP C10H12N5O10P2
-1.0
atp_c
ATP C10H12N5O13P3
1.0
h_c
H+
-1.0
h2o_c
H2O H2O
1.0
pi_c
Phosphate
1.0
smv_e
Simvastatin lactone form
-1.0
smv_c
Simvastatin lactone form

SMVtu in BiGG models:

Organism
Model
Homo sapiens
Recon3D

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External database links

Old identifiers

    SMVtu