BiGG Models

Gene: 5243_AT1

Descriptive name:

ABCB1

Model:

Position:

Left: 87504243 – Right: 87600184

Strand:

Minus

Chromosome:

Associated reactions:

BiGG ID

Name

Gene reaction rule

DIGALSGALSIDEATPte

Extracellular Transport of Digalactosylceramidesulfate, Active Transport

5243_AT1 or 4363_AT1

SPHMYLN_HsATPte

Extracellular Transport of Sphingomyeline, Active Transport

5243_AT1 or 4363_AT1

SPHMYLN180241_hs_ATPt

Transport of Sphingomyelin (D18:0/24:1), Active Transport

5243_AT1 or 4363_AT1

SPHMYLN18114_hs_ATPt

Transport of Sphingomyelin (D18:1/14:0), Active Transport

5243_AT1 or 4363_AT1

SPHMYLN18115_hs_ATPt

Transport of Sphingomyelin (D18:1/15:0), Active Transport

5243_AT1 or 4363_AT1

SPHMYLN18116_hs_ATPt

Transport of Sphingomyelin (D18:1/16:0), Active Transport

5243_AT1 or 4363_AT1

SPHMYLN181161_hs_ATPt

Transport of Sphingomyelin (D18:1/16:1), Active Transport

5243_AT1 or 4363_AT1

SPHMYLN18117_hs_ATPt

Transport of Sphingomyelin (D18:1/17:0), Active

5243_AT1 or 4363_AT1

SPHMYLN18118_hs_ATPt

Transport of Sphingomyelin (D18:1/18:0), Active

5243_AT1 or 4363_AT1

SPHMYLN181181_hs_ATPt

Transport of Sphingomyelin (D18:1/18:1), Active

5243_AT1 or 4363_AT1

SPHMYLN18120_hs_ATPt

Transport of Sphingomyelin (D18:1/20:0), Active

5243_AT1 or 4363_AT1

SPHMYLN181201_hs_ATPt

Transport of Sphingomyelin (D18:1/20:1), Active

5243_AT1 or 4363_AT1

SPHMYLN18121_hs_ATPt

Transport of Sphingomyelin (D18:1/21:0), Active

5243_AT1 or 4363_AT1

SPHMYLN18122_hs_ATPt

Transport of Sphingomyelin (D18:1/22:0), Active Transport

5243_AT1 or 4363_AT1

SPHMYLN181221_hs_ATPt

Transport of Sphingomyelin (D18:1/22:1), Active

5243_AT1 or 4363_AT1

SPHMYLN18123_hs_ATPt

Transport of Sphingomyelin (D18:1/23:0), Active

5243_AT1 or 4363_AT1

SPHMYLN1824_hs_ATPt

Transport of Sphingomyelin (D18:0/24:0), Active Transport

5243_AT1 or 4363_AT1

SPHMYLN1825_hs_ATPt

Transport of Sphingomyelin (D18:0/25:0), Active Transport

5243_AT1 or 4363_AT1

Transport of Androst-4-Ene-3, 17-Dione, Extracellular

Transport of 16Alpha-Hydroxydehydroepiandrosterone, Extracellular

Transport of 3Alpha-Hydroxy-5Beta-Androstan-17-One, Extracellular

Transport of 5Alpha-Androstane-3, 17-Dione, Extracellular

Transport of 5Alpha-Androstane-3Alpha, 17Beta-Diol, Extracellular

Transport of 2-Hydroxyestradiol-17Beta, Extracellular

Transport of 2-Methoxyestrone, Extracellular

Transport of 2-Methoxyestradiol-17Beta, Extracellular

Transport of 21-Hydroxyallopregnanolone, Extracellular

Transport of 11-Deoxycortisol, Extracellular

Transport of 11-Deoxycorticosterone, Extracellular

Transport of Pregnenolone, Extracellular

Transport of Allopregnanolone, Extracellular

Transport of 17Alpha-Hydroxyprogesterone, Extracellular

Transport of 17Alpha-Hydroxypregnenolone, Extracellular

Transport of 5Alpha-Pregnane-3, 20-Dione, Extracellular

Transport of Pregnenolone Sulfate, Extracellular

Transport of 17Alpha-Hydroxypregnenolone Sulfate, Extracellular

2HATVACIDGLUCteb

Efflux of 2-hydroxy-atorvastatin-acyl-glucuronide into bile

1244_AT1 or 5243_AT1

Efflux of 2-hydroxy-atorvastatin-acid into bile

1244_AT1 or 5243_AT1

2HATVLACGLUCteb

Efflux of 2-hydroxy-atorvastatin-lactone-glucuronide into bile

1244_AT1 or 5243_AT1

Efflux of 2-hydroxy-atorvastatin-lactone into bile

1244_AT1 or 5243_AT1

Efflux of 4-hydroxy-atorvastatin-acid into bile

1244_AT1 or 5243_AT1

Efflux of 4-hydroxy-atorvastatin-lactone into bile

1244_AT1 or 5243_AT1

Release of 6-exomethylene-lovastatin-acid form into bile

Efflux of acetaminophen by P-gp from the enterocytes into lumen

Efflux of atorvastatin acid by P-gp from the enterocytes into lumen

Efflux of atorvastatin lactone by P-gp from the enterocytes into lumen

Efflux of cerivastatin by P-gp or BCRP from the enterocytes into lumen

5243_AT1 or 9429_AT1

Efflux of cyclosporine by P-gp from the enterocytes into lumen

Release of 3-hydroxy-iso-delta-4,5-hydroxy acid form of lovastatin into bile

Efflux of losartan by P-gp from the enterocytes into lumen

Efflux of lovastatin acid by P-gp from the enterocytes into lumen

Efflux of lovastatin lactone by P-gp from the enterocytes into lumen

Efflux of midazolam by P-gp from the enterocytes into lumen

Efflux of simvastatin dihydroxy acid form into bile

Efflux of simvastatin by P-gp from the enterocytes into lumen

Efflux of tacrolimus into intestinal lumen by P-gp

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External database links

Online Mendelian Inheritance in Man: 171050
Human Protein Reference Database: 01370
NCBI Entrez Gene: 5243
CCDS: CCDS5608.1

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Old identifiers

5243.1