Reaction: HMR_0981

Descriptive name:

Leukotriene-B4 20-Monooxygenase

Model:

Recon3D

Reaction:

h_c + nadph_c + o2_c + CE6246_c → h2o_c + nadp_c + CE6247_c

Metabolites:

Stoichiometry
BiGG ID
Name
-1.0
h_c
H+
1.0
h2o_c
H2O H2O
1.0
nadp_c
Nicotinamide adenine dinucleotide phosphate
-1.0
nadph_c
Nicotinamide adenine dinucleotide phosphate - reduced
-1.0
o2_c
O2 O2
1.0
CE6247_c
5,12,20-TriHETE
-1.0
CE6246_c
5,12-Dihydroxy-6,8,10,14-Eicosatetraenoic Acid

Default bounds:

(0.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Arachidonic acid metabolism

Gene Reaction Rule:

57834_AT1 or 126410_AT1 or 8529_AT1 or 11283_AT1 or 4051_AT1

Genes:

11283_AT1 (CYP4F8)
8529_AT1 (CYP4F2)
4051_AT1 (CYP4F3)
57834_AT1 (CYP4F11)
126410_AT1 (CYP4F22)

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Universal reaction ?

External database links

Old identifiers

    HMR_0981

HMR_0981 in other models