21HPRGNLONE

Formation of 21-Hydroxypregnenolone

25HVITD3c

1-alpha hydroxylation of 25-hydroxy vitamin D

2AMACSULT

2-Aminoacrylate sulfotransferase

34DHPEAR

3, 4-Dihydroxyphenylethanol:NADP+ Reductase

34DHPLACOX_NADP

34DHPLACOX LPAREN NADP RPAREN

34DHXMANDACOX_NADP

3,4-Dihydroxymandelaldehyde:NADP+ oxidoreductase

3DHCAS

3-dehydrocholic acid formation

3DHCDCAS

3-dehydro-chenodehydroxycholic acid formation

3DHDCAS

3-dehydro-deoxycholic acid formation

3DHLCAS

3-dehydro-lithocholic acid formation

3DSPHR

3 Dehydrosphinganine reductase

3HPPPNOHc

Hydroxylation of 3- (3-Hydroxyphenyl)Propionate

3MGLUTRc

Formation of 3-Methyl-Glutarate

3MOX4HOXPGALDOX_NADP

3-Methoxy-4-hydroxyphenylglycolaldehyde:NADP+ oxidoreductase

4HOXPACDOX_NADP

4HOXPACDOX LPAREN NADP RPAREN

5OHHEXAc

Formation of 5-Hydroxy-Hexanoate

7KLITCHOLc

Formation of 7-Ketolithocholate

7OHOCTAc

Formation of 7-Hydroxy-Octanoate

ACTLMO

Acetol monooxygenase

ACTNMO

Acetone monooxygenase

AKR1C1

Aldo-keto reductase family 1, member C1 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)

AKR1D

Aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)

AKR1D2

Aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)

ALCD19y

Alcohol dehydrogenase glycerol NADP

ALCD2y

Alcohol dehydrogenase (ethanol, NADP)

ALDD19x_P

Aldehyde dehydrogenase (phenylacetaldehyde, NADP)

ALDD2y

Aldehyde dehydrogenase (acetaldehyde, NADP)

ALR

Aldose reductase

ALR2

Aldose reductase (methylglyoxal)

ALR3

Aldose reductase (acetol)

AM1ALCShr

Formation of AM1AL-cyclosporine in hepatocytes

AMCOXO

2-aminomuconate reductase

AND19ONEc

Hydroxylation of Androst-4-Ene-3, 17-Dione

ARABR

Arabinose reductase

BETALDHy

Betaine-aldehyde dehydrogenase

BILIRED

Nad(p)h biliverdin reductase

C14825c

Formation of 9 (10)-Epome

C14STR

C 14 sterol reductase

CBR2

Carbonyl reductase [NADPH] 1

CDCA6AH

Chenodeoxycholic acid 6alpha-hydroxylase

CYP2R1

Vitamin D3 25-hydroxylase

DASCBR_1

Dehydroascorbate Reductase

DEDOLR_L

Dehydrodolichol reductase (liver)

DES21

Sphingolipid C-4 Hydroxylase (Des2)

DESAT16

Palmitoyl CoA desaturase n C160CoA n C161CoA

DESAT18

Stearoyl CoA desaturase n C180CoA n C181CoA

DHCRD1

Dihydroceramide desaturase

DHFR

Dihydrofolate reductase

DHGLZhc

Dehydrogenation of gliclazide to dehydro-gliclazide in hepatocytes

DOPAc

Formation of Dopamine

DSMSTOLR

Desmosterol reductase

DURAD

Dihydrouracil dehydrogenase (NADP)

DURAD2

Dihydrothymin dehydrogenase (NADP)

ECOAR

Trans-2-enoyl-CoA reductase (18:0) (NADPH)

ETOHMO

Ethanol monooxygenase

FADRx2

FAD reductase

FAEL183

Fatty-acyl-CoA elongation (n-C18:3CoA)

FAEL184

Fatty-acyl-CoA elongation (n-C20:4CoA)

FAEL204

Fatty-acyl-CoA elongation (n-C20:4CoA)

FAEL205

Fatty-acyl-CoA elongation (n-C20:5CoA)

FAH1

Fatty acid omega-hydroxylase

FAH2

Fatty acid omega-hydroxylase

FAH3_1

Fatty Acid Omega-Hydroxylase

FAS100COA

Fatty acyl CoA synthase n C100CoA

FAS120COA

Fatty acyl CoA synthase n C120CoA

FAS140COA

Fatty acyl CoA synthase n C140CoA

FAS160COA

Fatty acyl CoA synthase n C160CoA

FAS180

Fatty acid synthase n C180

FAS180COA

Fatty acyl CoA synthase n C180CoA

FAS80COA_L

Fatty acyl CoA synthase n C80CoA lumped reaction

FOLR2

Folate reductase

FTHFDH

10-formyltetrahydrofolate:NADP+ oxidoreductase

G3PD2

Glycerol-3-phosphate dehydrogenase (NADP)

G6PDH2c

Glucose 6-Phosphate Dehydrogenase

G6PDH2r

Glucose 6-phosphate dehydrogenase

GALOR

D-Galactose:NADP+ 1-oxidoreductase

GFUCS

GDP-L-fucose synthase

GLRASE

Glucuronolactone reductase

GLYCLTDy

Glycolate dehydrogenase (NADP)

GMPR

GMP reductase

GND

Phosphogluconate dehydrogenase

GNDc

Phosphogluconate Dehydrogenase

GTHOr

Glutathione oxidoreductase

GULND

Gulonate dehydrogenase

H2O2syn

Hydrogen peroxide synthesis (NADPH dependent)

HC02194c

Formation of Ursodeoxycholate

HMGCOAR

Hydroxymethylglutaryl CoA reductase

HMR_0942

Unspecific Monooxygenase

HMR_0946

Unspecific Monooxygenase

HMR_0950

HMR 0950

HMR_0954

HMR 0954

HMR_0980

Carbonyl Reductase (NADPH)

HMR_0981

Leukotriene-B4 20-Monooxygenase

HMR_1126

Leukotriene-B4 20-Monooxygenase

HMR_1280

Carbonyl Reductase (NADPH)

HMR_1329

(5Z, 13E)- (15S)-9Alpha, 11Alpha, 15-Trihydroxyprosta-5, 13-Dienoate:NADP+ 11-Oxidoreductase

HMR_1467

Presqualene-Diphosphate Diphosphate-Lyase (Reducing, Squalene-Forming)

HMR_1477

Sterol 14Alpha-Demethylase

HMR_1478

Sterol 14Alpha-Demethylase

HMR_1479

Sterol 14Alpha-Demethylase

HMR_1490

Methylsterol Monooxygenase

HMR_1493

Methylsterol Monooxygenase

HMR_1494

Methylsterol Monooxygenase

HMR_1495

3Beta-Hydroxysteroid-4Alpha-Carboxylate 3-Dehydrogenase (Decarboxylating)

HMR_1500

3Beta-Hydroxysteroid 3-Dehydrogenase

HMR_1502

Methylsterol Monooxygenase

HMR_1503

Methylsterol Monooxygenase

HMR_1504

Methylsterol Monooxygenase

HMR_1505

3Beta-Hydroxysteroid-4Alpha-Carboxylate 3-Dehydrogenase (Decarboxylating)

HMR_1509

3Beta-Hydroxysteroid 3-Dehydrogenase

HMR_1516

HMR 1516

HMR_1536

Sterol 14Alpha-Demethylase

HMR_1538

Sterol 14Alpha-Demethylase

HMR_1539

Sterol 14Alpha-Demethylase

HMR_1540

Delta14-Sterol Reductase

HMR_1543

Methylsterol Monooxygenase

HMR_1544

Methylsterol Monooxygenase

HMR_1545

Methylsterol Monooxygenase

HMR_1546

3Beta-Hydroxysteroid-4Alpha-Carboxylate 3-Dehydrogenase (Decarboxylating)

HMR_1547

3Beta-Hydroxysteroid 3-Dehydrogenase

HMR_1548

Methylsterol Monooxygenase

HMR_1549

Methylsterol Monooxygenase

HMR_1550

Methylsterol Monooxygenase

HMR_1551

3Beta-Hydroxysteroid-4Alpha-Carboxylate 3-Dehydrogenase (Decarboxylating)

HMR_1552

3Beta-Hydroxysteroid 3-Dehydrogenase

HMR_1565

Cholesterol:NADP+ Delta7-Oxidoreductase

HMR_1681

Cholestanetriol 26-Monooxygenase

HMR_1735

Cholesterol 24-Hydroxylase

HMR_1737

24-Hydroxycholesterol 7Alpha-Hydroxylase

HMR_1739

7Alpha-Hydroxycholest-4-En-3-One 12Alpha-Hydroxylase

HMR_1740

Delta4-3-Oxosteroid 5Beta-Reductase

HMR_1741

Delta4-3-Oxosteroid 5Beta-Reductase

HMR_1742

3Alpha-Hydroxysteroid 3-Dehydrogenase (Si-Specific)

HMR_1743

3Alpha-Hydroxysteroid 3-Dehydrogenase (Si-Specific)

HMR_1765

25/26-Hydroxycholesterol 7Alpha-Hydroxylase

HMR_1767

7Alpha-Hydroxycholest-4-En-3-One 12Alpha-Hydroxylase

HMR_1768

Delta4-3-Oxosteroid 5Beta-Reductase

HMR_1769

Delta4-3-Oxosteroid 5Beta-Reductase

HMR_1770

3Alpha-Hydroxysteroid 3-Dehydrogenase (Si-Specific)

HMR_1771

3Alpha-Hydroxysteroid 3-Dehydrogenase (Si-Specific)

HMR_1786

Cholesterol 25-Hydroxylase

HMR_1838

Lithocholic acid 1beta-hydroxylase

HMR_1940

Pregnenolone, Hydrogen-Donor:Oxygen Oxidoreductase (21-Hydroxylating)

HMR_1944

Steroid 17Alpha-Monooxygenase

HMR_1948

17Alpha-Hydroxypregnenolone, Hydrogen-Donor:Oxygen Oxidoreductase (21-Hydroxylating)

HMR_1958

17Alpha-Hydroxypregnenolone Acetaldehyde-Lyase

HMR_1976

3-Oxo-5Alpha-Steroid 4-Dehydrogenase (NADP+)

HMR_1981

Steroid 17Alpha-Monooxygenase

HMR_1988

Steroid 21-Monooxygenase

HMR_1989

Steroid, Reduced-Adrenal-Ferredoxin:Oxygen Oxidoreductase (11-Hydroxylating)

HMR_1990

21-Deoxycortisol, Hydrogen-Donor:Oxygen Oxidoreductase (21-Hydroxylating)

HMR_1991

Steroid, Hydrogen-Donor:Oxygen Oxidoreductase (17-Alpha-Hydroxylating)

HMR_1992

11Beta-Hydroxyprogesterone, Hydrogen-Donor:Oxygen Oxidoreductase (21-Hydroxylating)

HMR_1993

Progesterone, Reduced Ferredoxin:Oxygen Oxidoreductase (11-Hydroxylating)

HMR_1996

11Beta-Hydroxysteroid Dehydrogenase

HMR_2002

Transferred to 1.3.1.30 And 1.3.1.22

HMR_2007

Steroid 21-Monooxygenase

HMR_2014

Delta4-3-Oxosteroid 5Beta-Reductase

HMR_2018

3 (Or 17)Alpha-Hydroxysteroid Dehydrogenase

HMR_2210

Very-Long-Chain Enoyl Coenzyme A Reductase

HMR_2217

Very-Long-Chain 3-Oxoacyl Coenzyme A Reductase

HMR_2219

Very-Long-Chain Enoyl Coenzyme A Reductase

HMR_2260

Very-Long-Chain 3-Oxoacyl Coenzyme A Reductase

HMR_2262

Very-Long-Chain Enoyl Coenzyme A Reductase

HMR_2264

Very-Long-Chain 3-Oxoacyl Coenzyme A Reductase

HMR_2266

Very-Long-Chain Enoyl Coenzyme A Reductase

HMR_2268

Very-Long-Chain 3-Oxoacyl Coenzyme A Reductase

HMR_2270

Very-Long-Chain Enoyl Coenzyme A Reductase

HMR_2281

Stearoyl Coenzyme A 9-Desaturase

HMR_2282

Stearoyl Coenzyme A 9-Desaturase

HMR_2284

Stearoyl Coenzyme A 9-Desaturase

HMR_2287

Stearoyl Coenzyme A 9-Desaturase

HMR_2288

Stearoyl Coenzyme A 9-Desaturase

HMR_2289

Stearoyl Coenzyme A 9-Desaturase

HMR_2292

Stearoyl Coenzyme A 9-Desaturase

HMR_2293

Stearoyl Coenzyme A 9-Desaturase

HMR_2295

Stearoyl Coenzyme A 9-Desaturase

HMR_2296

Stearoyl Coenzyme A 9-Desaturase

HMR_2334

Very-Long-Chain 3-Oxoacyl Coenzyme A Reductase

HMR_2338

Very-Long-Chain Enoyl Coenzyme A Reductase

HMR_2343

Very-Long-Chain 3-Oxoacyl Coenzyme A Reductase

HMR_2345

Very-Long-Chain Enoyl Coenzyme A Reductase

HMR_2348

Very-Long-Chain 3-Oxoacyl Coenzyme A Reductase

HMR_2350

Very-Long-Chain Enoyl Coenzyme A Reductase

HMR_2354

Very-Long-Chain 3-Oxoacyl Coenzyme A Reductase

HMR_2356

Very-Long-Chain Enoyl Coenzyme A Reductase

HMR_2359

HMR 2359

HMR_2362

Very-Long-Chain 3-Oxoacyl Coenzyme A Reductase

HMR_2364

Very-Long-Chain Enoyl Coenzyme A Reductase

HMR_2365

HMR 2365

HMR_2368

Linoleoyl Coenzyme A, Ferrocytochrome B5:Oxygen Oxidoreductase (6, 7 Cis-Dehydrogenating)

HMR_2374

HMR 2374

HMR_2380

HMR 2380

HMR_2391

HMR 2391

HMR_2393

HMR 2393

HMR_2403

HMR 2403

HMR_2434

Very-Long-Chain 3-Oxoacyl Coenzyme A Reductase

HMR_2436

Very-Long-Chain Enoyl Coenzyme A Reductase

HMR_2457

Unspecific Monooxygenase

HMR_2472

HMR 2472

HMR_2484

HMR 2484

HMR_2495

HMR 2495

HMR_2533

Very-Long-Chain 3-Oxoacyl Coenzyme A Reductase

HMR_2537

Very-Long-Chain Enoyl Coenzyme A Reductase

HMR_2541

Very-Long-Chain 3-Oxoacyl Coenzyme A Reductase

HMR_2543

Very-Long-Chain Enoyl Coenzyme A Reductase

HMR_2581

Prostaglandin-Endoperoxide Synthase

HMR_2585

Prostaglandin-Endoperoxide Synthase

HMR_3855

Propane-1, 2-Diol:NAD+ 1-Oxidoreductase

HMR_4079

Aldehyde Dehydrogenase (NAD+)

HMR_4700

N, N-Dimethylglycine:Electron-Transfer Flavoprotein Oxidoreductase (Demethylating)

HMR_4702

HMR 4702

HMR_6826

Thyroxine 5'-Deiodinase

HMR_6834

Thyroxine 5'-Deiodinase

HMR_6854

L-Thyroxine Iodohydrolase (Reducing)

HOXG

Heme oxygenase 1

HPROb

L hydroxyproline reductase NADP

HPYRRy

Hydroxypyruvate reductase (NADPH)

HSD17B1

Testicular 17-beta-hydroxysteroid dehydrogenase

ICDHyr

Isocitrate dehydrogenase (NADP)

KAS8

B-ketoacyl synthetase (palmitate, n-C16:0)

KYN3OX

Kynurenine 3 monooxygenase

LALDO2

D-Lactaldehyde:NADP+ 1-oxidoreductase

LNS14DM

Cytochrome P450 lanosterol 14 alpha demethylase NADP

LTHSTRLOR

Lathosterol, NADPH:oxygen 5-oxidoreductase

ME2

Malic enzyme (NADP)

MELATNOX

Melatonin:NADP oxidoreductase

MTHFD

Methylenetetrahydrofolate dehydrogenase (NADP)

MTHFR3

5 10 methylenetetrahydrofolatereductase NADPH

NADK

NAD kinase

NADPN

NADP nucleosidase

NADPPPS

NADP phosphatase

NADPQNOXR

Dt-Diaphorase: NADP Quinone Oxireductase

NADPtru

NADP transporter, endoplasmic reticulum

NADPtxu

NADP transport, glyoxysome

NFDOXDhc

Oxidation of nifepine to nitropyridine metabolite in hepatocytes

NOS1

L-Arginine,NADPH:oxygen oxidoreductase (N-(omega)-hydroxyarginine-forming)

NOS2

Nitric Oxide Synthase (NO forming)

NOS2_2

Nitric Oxide Synthase (No Forming)

P4502A6

Cytochrome P450 2A6

P4502C18

Cytochrome P450 2C18

P4502C19

Cytochrome P450 2C19

P4502C8

Cytochrome P450 2C8

P4502C9

Cytochrome P450 2C9

P4502C92

Cytochrome P450 2C9

P4502C93

Cytochrome P450 2C9

P4502C94

Cytochrome P450 2C9

P4502D6

Cytochrome P450 2D6

P4502E1

Cytochrome P450 2E1

P4502F1

Cytochrome P450 2F1

P4503A4

Cytochrome P450 3A4

P4503A5

Cytochrome P450 3A5

P5CR

Pyrroline-5-carboxylate reductase

PGS

Prostaglandin G/H synthase

PPDOy

Propane-1,2-diol:NADP+ 1-oxidoreductase

r0027

NADPH:CoA-glutathione oxidoreductase EC:1.8.1.9

r0145

L-Arginine, NADPH:Oxygen Oxidoreductase (Nitric-Oxide-Forming)

r0398

NADPH:6,7-dihydropteridine oxidoreductase Folate biosynthesis EC:1.5.1.34

r0402

Tetrahydrobiopterin:NADP+ oxidoreductase Folate biosynthesis EC:1.1.1.153

r0422

Isocitrate:NADP+ oxidoreductase (decarboxylating) Citrate cycle (TCA cycle) EC:1.1.1.42

r0673

6-Lactoyl-5,6,7,8-tetrahydropterin:NADP+ 2-oxidoreductase Folate biosynthesis EC:1.1.1.220

r0741

5Beta-Cholestane-3Alpha, 7Alpha, 12Alpha-Triol, NADPH:Oxygen Oxidoreductase (26-Hydroxylating) Bile Acid Biosynthesis

r0747

3alpha,7alpha-Dihydroxy-5beta-cholestane:NADP+ oxidoreductase (B-specific); 3alpha,7alpha-Dihydroxy-5beta-cholestane:NADP+ oxidoreductase Bile acid biosynthesis EC:1.1.1.50

r0750

3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane:NADP+ oxidoreductase (B-specific); 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane:NADP+ oxidoreductase Bile acid biosynthesis EC:1.1.1.50

r1457

Hexadecanal:NADP+ delta2-oxidoreductase EC:1.3.1.27

RADH2

Retinal dehydrogenase (NADPH)

RADH4

Retinal dehydrogenase (NADPH)

RAHY

Retinoic acid hydroxylation (P450)

RDH1a

Retinol dehydrogenase (all-trans,NADPH)

RDH2a

Retinol dehydrogenase (9-cis,NADPH)

RDH3a

Retinol dehydrogenase (11-cis,NADPH)

RE0566C

RE0566

RE0568C

RE0568

RE0570C

RE0570

RE0574C

RE0574

RE0576C_1

RE0576C

RE0581C

RE0581

RE1096C

RE1096

RE1134C

RE1134

RE1587C

Quinine 3-Monooxygenase

RE1632C

Quinine 3-Monooxygenase

RE1711C

Alcohol Dehydrogenase

RE1803C

RE1803

RE1807C

RE1807

RE1826C

RE1826

RE2112C

RE2112

RE2235C

Unspecific Monooxygenase

RE2240C

RE2240

RE2407C

RE2407C

RE2410C

7-Dehydrocholesterol Reductase

RE2526C

NADPH:Quinone Reductase

RE2626C

RE2626

RE2636C

RE2636

RE2675C2

Re2675C2

RE2766C

17Beta-Estradiol 17-Dehydrogenase

RE2799C

Prostaglandin-F Synthase

RE3013C

Unspecific Monooxygenase

RE3041C

Arachidonate 5-Lipoxygenase

RE3104C

RE3104

RE3106C

RE3106

RE3108C

3Alpha-Hydroxysteroid 3-Dehydrogenase (Si-Specific)

RE3112C

RE3112

RE3119C

RE3119

RE3121C

RE3121

RE3134C

Delta14-Sterol Reductase

RE3152C

RE3152

RE3154C

RE3154

RE3162C

RE3162

RE3164C

RE3164

RE3166C

RE3166

RE3168C

RE3168

RE3169C

RE3169

RE3171C

RE3171

RE3173C

RE3173

RE3175C

RE3175

RE3227C

RE3227

RE3229C

RE3229

RE3230C

RE3230

RE3232C

RE3232

RE3234C

RE3234

RE3236C

RE3236

RE3242C

RE3242

RE3244C

RE3244

RE3251C

RE3251

RE3307C

Carbonyl Reductase (NADPH)

RE3432C

Carbonyl Reductase (NADPH)

RE3434C

Leukotriene-B4 20-Monooxygenase

RE3435C

Leukotriene-B4 20-Monooxygenase

RE3436C

Leukotriene-B4 20-Monooxygenase

RE3470C

Carbonyl Reductase (NADPH)

RE3476C

Carbonyl Reductase (NADPH)

RE3597C

Carbonyl Reductase (NADPH)

SBTR

D sorbitol reductase

SK_nadp_c

Sink nadp[c]

SMO

Squalene monooxygenase

SPR

Sepiapterin reductase

TCDCA6AH

Taurochenodeoxycholic acid 6alpha-hydroxylase

TRDR

Thioredoxin reductase (NADPH)

TRDR2

Thioredoxin (ubiquinone 10) reductase (NADPH)

TYMc

Formation of Tyraminium

XYLR

Xylose reductase

XYLUR

Xylulose reductase