Reaction: HMR_2018

Descriptive name:

3 (Or 17)Alpha-Hydroxysteroid Dehydrogenase

Model:

Recon3D

Reaction:

h_c + nadph_c + andrstandn_c → nadp_c + andrstrn_c

Metabolites:

Stoichiometry
BiGG ID
Name
-1.0
h_c
H+
1.0
nadp_c
Nicotinamide adenine dinucleotide phosphate
-1.0
nadph_c
Nicotinamide adenine dinucleotide phosphate - reduced
1.0
andrstrn_c
Andrstrn c
-1.0
andrstandn_c
5alpha-androstane-3,17-dione

Default bounds:

(0.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Androgen and estrogen synthesis and metabolism

Gene Reaction Rule:

1646_AT1 or 1645_AT1 or 8644_AT1 or 1109_AT1

Genes:

1645_AT1 (AKR1C1)
1109_AT1 (AKR1C4)
8644_AT1 (AKR1C3)
1646_AT1 (AKR1C2)

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Universal reaction ?

External database links

Old identifiers

    HMR_2018

HMR_2018 in other models