Reaction: r0741

Descriptive name:

5Beta-Cholestane-3Alpha, 7Alpha, 12Alpha-Triol, NADPH:Oxygen Oxidoreductase (26-Hydroxylating) Bile Acid Biosynthesis

Model:

Recon3D

Reaction:

h_c + nadph_c + o2_c + xoltriol_c → h2o_c + nadp_c + xoltetrol_c

Metabolites:

Stoichiometry
BiGG ID
Name
-1.0
h_c
H+
1.0
h2o_c
H2O H2O
1.0
nadp_c
Nicotinamide adenine dinucleotide phosphate
-1.0
nadph_c
Nicotinamide adenine dinucleotide phosphate - reduced
-1.0
o2_c
O2 O2
-1.0
xoltriol_c
3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane
1.0
xoltetrol_c
3alpha,7alpha,12alpha,26-Tetrahydroxy-5beta-cholestane

Default bounds:

(0.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Bile acid synthesis

Gene Reaction Rule:

1593_AT1

Genes:

1593_AT1 (CYP27A1)

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Universal reaction ?

External database links

Old identifiers

    r0741

r0741 in other models