Reaction: MTHFD

Descriptive name:

Methylenetetrahydrofolate dehydrogenase (NADP)

Model:

Recon3D

Reaction:

mlthf_c + nadp_c ⇌ methf_c + nadph_c

Metabolites:

Stoichiometry
BiGG ID
Name
1.0
methf_c
5,10-Methenyltetrahydrofolate
-1.0
mlthf_c
5,10-Methylenetetrahydrofolate
-1.0
nadp_c
Nicotinamide adenine dinucleotide phosphate
1.0
nadph_c
Nicotinamide adenine dinucleotide phosphate - reduced

Default bounds:

(-1000.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Folate metabolism

Gene Reaction Rule:

4522_AT1 or 4524_AT1

Genes:

4522_AT1 (MTHFD1)
4524_AT1 (MTHFR)

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Universal reaction ?

External database links

Provided by MetaNetX (CC BY 4.0)

Old identifiers

    MTHFD

MTHFD in other models