Reaction: MTHFD

Descriptive name:

Methylenetetrahydrofolate dehydrogenase (NADP)

Model:

iJN1463

Reaction:

mlthf_c + nadp_c ⇌ methf_c + nadph_c

Metabolites:

Stoichiometry
BiGG ID
Name
1.0
methf_c
5,10-Methenyltetrahydrofolate
-1.0
mlthf_c
5,10-Methylenetetrahydrofolate
-1.0
nadp_c
Nicotinamide adenine dinucleotide phosphate
1.0
nadph_c
Nicotinamide adenine dinucleotide phosphate - reduced

Default bounds:

(-999999.0, 999999.0)

Objective coefficient:

0.0

Subsystem:

S_Cofactor_and_Prosthetic_Group_Biosynthesis__One_Carbon_pool_by_folate

Gene Reaction Rule:

PP_1945 or PP_2265

Genes:

PP_1945 (folD-I)
PP_2265 (folD-II)

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Universal reaction ?

External database links

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Old identifiers

    MTHFD

MTHFD in other models