Reaction: HMR_1478

Descriptive name:

Sterol 14Alpha-Demethylase

Model:

Recon3D

Reaction:

h_c + nadph_c + o2_c + M00939_c → 2.0 h2o_c + nadp_c + M00937_c

Metabolites:

Stoichiometry
BiGG ID
Name
-1.0
h_c
H+
2.0
h2o_c
H2O H2O
1.0
nadp_c
Nicotinamide adenine dinucleotide phosphate
-1.0
nadph_c
Nicotinamide adenine dinucleotide phosphate - reduced
-1.0
o2_c
O2 O2
-1.0
M00939_c
4,4-Dimethyl-14Alpha-Hydroxymethyl-5Alpha-Cholesta-8,24-Dien-3Beta-Ol
1.0
M00937_c
4,4-Dimethyl-14Alpha-Formyl-5Alpha-Cholesta-8,24-Dien-3Beta-Ol

Default bounds:

(0.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Cholesterol metabolism

Gene Reaction Rule:

1595_AT1

Genes:

1595_AT1 (CYP51A1)

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Universal reaction ?

External database links

Old identifiers

    HMR_1478

HMR_1478 in other models