Reaction: HMGCOAR

Descriptive name:

Hydroxymethylglutaryl CoA reductase

Model:

Recon3D

Reaction:

coa_c + 2.0 nadp_c + mev__R_c ⇌ 2.0 h_c + 2.0 nadph_c + hmgcoa_c

Metabolites:

Stoichiometry
BiGG ID
Name
-1.0
coa_c
Coenzyme A
2.0
h_c
H+
-2.0
nadp_c
Nicotinamide adenine dinucleotide phosphate
2.0
nadph_c
Nicotinamide adenine dinucleotide phosphate - reduced
1.0
hmgcoa_c
Hydroxymethylglutaryl CoA C27H39N7O20P3S
-1.0
mev__R_c
R Mevalonate C6H11O4

Default bounds:

(-1000.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Cholesterol metabolism

Gene Reaction Rule:

3156_AT1

Genes:

3156_AT1 (HMGCR)

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Universal reaction ?

External database links

Provided by MetaNetX (CC BY 4.0)

Old identifiers

    r0488

HMGCOAR in other models