Reaction: KAS8

Descriptive name:

B-ketoacyl synthetase (palmitate, n-C16:0)

Model:

Recon3D

Reaction:

accoa_c + 20.0 h_c + 7.0 malcoa_c + 14.0 nadph_c → 7.0 co2_c + 8.0 coa_c + 6.0 h2o_c + hdca_c + 14.0 nadp_c

Metabolites:

Stoichiometry
BiGG ID
Name
-1.0
accoa_c
Acetyl-CoA
7.0
co2_c
CO2 CO2
8.0
coa_c
Coenzyme A
-20.0
h_c
H+
6.0
h2o_c
H2O H2O
1.0
hdca_c
Hexadecanoate (n-C16:0)
-7.0
malcoa_c
Malonyl CoA C24H33N7O19P3S
14.0
nadp_c
Nicotinamide adenine dinucleotide phosphate
-14.0
nadph_c
Nicotinamide adenine dinucleotide phosphate - reduced

Default bounds:

(0.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Fatty acid synthesis

Gene Reaction Rule:

2194_AT1 or ((2194_AT1 and 79071_AT1) and 60481_AT1 and 54898_AT1)

Genes:

54898_AT1 (ELOVL2)
60481_AT1 (ELOVL5)
79071_AT1 (ELOVL6)
2194_AT1 (FASN)

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Universal reaction ?

External database links

Provided by MetaNetX (CC BY 4.0)

Old identifiers

    KAS8

KAS8 in other models