Reaction: r0750

Descriptive name:

3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane:NADP+ oxidoreductase (B-specific); 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane:NADP+ oxidoreductase Bile acid biosynthesis EC:1.1.1.50

Model:

Recon3D

Reaction:

nadp_c + xoltriol_c ⇌ h_c + nadph_c + xoldioloneh_c

Metabolites:

Stoichiometry
BiGG ID
Name
1.0
h_c
H+
-1.0
nadp_c
Nicotinamide adenine dinucleotide phosphate
1.0
nadph_c
Nicotinamide adenine dinucleotide phosphate - reduced
1.0
xoldioloneh_c
7alpha,12alpha-Dihydroxy-5beta-cholestan-3-one
-1.0
xoltriol_c
3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane

Default bounds:

(-1000.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Bile acid synthesis

Gene Reaction Rule:

1109_AT1

Genes:

1109_AT1 (AKR1C4)

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Universal reaction ?

External database links

Provided by MetaNetX (CC BY 4.0)

Old identifiers

    r0750

r0750 in other models