Reaction: P4503A4

Descriptive name:

Cytochrome P450 3A4

Model:

Recon3D

Reaction:

h_c + nadph_c + o2_c + nifedipine_c → h2o_c + nadp_c + hnifedipine_c

Metabolites:

Stoichiometry
BiGG ID
Name
-1.0
h_c
H+
1.0
h2o_c
H2O H2O
1.0
nadp_c
Nicotinamide adenine dinucleotide phosphate
-1.0
nadph_c
Nicotinamide adenine dinucleotide phosphate - reduced
-1.0
o2_c
O2 O2
1.0
hnifedipine_c
Hnifedipine c
-1.0
nifedipine_c
Nifedipine c

Default bounds:

(0.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Cytochrome metabolism

Gene Reaction Rule:

1576_AT1

Genes:

1576_AT1 (CYP3A4)

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Universal reaction ?

External database links

Provided by MetaNetX (CC BY 4.0)

Old identifiers

    P4503A4

P4503A4 in other models