Reaction: 2HATVACIDhc

Descriptive name:

Conversion of 2-hydroxy-atorvastatin-lactone to its acid form in hepatocytes

Model:

Recon3D

Reaction:

h2o_c + 2hatvlac_c → h_c + 2hatvacid_c

Metabolites:

Stoichiometry
BiGG ID
Name
1.0
h_c
H+
-1.0
h2o_c
H2O H2O
1.0
2hatvacid_c
2-hydroxy-atorvastatin-acid / ortho-hydroxy-atorvastatin acid
-1.0
2hatvlac_c
2-hydroxy-atorvastatin-lactone / ortho-hydroxy-atorvastatin lactone

Default bounds:

(0.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Drug metabolism

Gene Reaction Rule:

5446_AT1

Genes:

5446_AT1 (PON3)

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Universal reaction ?

External database links

Old identifiers

    2HATVACIDhc

2HATVACIDhc in other models