Reaction: LVSTACIDhep

Descriptive name:

Conversion of pro-durg lovastatin to active hydroxyacid form in hepatocytes

Model:

Recon3D

Reaction:

h2o_c + lvst_c → h_c + lvstacid_c

Metabolites:

Stoichiometry
BiGG ID
Name
1.0
h_c
H+
-1.0
h2o_c
H2O H2O
1.0
lvstacid_c
Lovastatin-hydroxyacid form
-1.0
lvst_c
Lovastatin lactone form

Default bounds:

(0.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Drug metabolism

Gene Reaction Rule:

5446_AT1

Genes:

5446_AT1 (PON3)

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Universal reaction ?

External database links

Old identifiers

    LVSTACIDhep

LVSTACIDhep in other models