Reaction: ALLOPOXDhep

Descriptive name:

Oxidation of allopurinol to oxypurinol in hepatocytes

Model:

Recon3D

Reaction:

h2o_c + o2_c + allop_c → h2o2_c + oxyp_c

Metabolites:

Stoichiometry
BiGG ID
Name
-1.0
h2o_c
H2O H2O
1.0
h2o2_c
Hydrogen peroxide
-1.0
o2_c
O2 O2
-1.0
allop_c
Allopurinol
1.0
oxyp_c
Oxypurinol

Default bounds:

(0.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Drug metabolism

Gene Reaction Rule:

7498_AT1 or 316_AT1

Genes:

316_AT1 (AOX1)
7498_AT1 (XDH)

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Universal reaction ?

External database links

Old identifiers

    ALLOPOXDhep

ALLOPOXDhep in other models