Reaction: 4HATVACIDhc

Descriptive name:

Conversion of 4-hydroxy-atorvastatin-lactone to its acid form in hepatocytes

Model:

Recon3D

Reaction:

h2o_c + 4hatvlac_c → h_c + 4hatvacid_c

Metabolites:

Stoichiometry
BiGG ID
Name
1.0
h_c
H+
-1.0
h2o_c
H2O H2O
-1.0
4hatvlac_c
4-hydroxy-atorvastatin-lactone / para-hydroxy-atorvastatin lactone
1.0
4hatvacid_c
4-hydroxy-atorvastatin-acid / para-hydroxy-atorvastatin acid

Default bounds:

(0.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Drug metabolism

Gene Reaction Rule:

5446_AT1

Genes:

5446_AT1 (PON3)

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Universal reaction ?

External database links

Old identifiers

    4HATVACIDhc

4HATVACIDhc in other models