BiGG Models

Metabolite: h_c

Descriptive name:

H+

Model:

Formula:

H

Charge:

1

Compartment:

Reactions:

BiGG ID

Name

N1-Methylnicotinamide transport

2 3 cyclic nucleotide 2 phosphodiesterase 2 3 cyclic UMP

1-alpha hydroxylation of 25-hydroxy vitamin D

2 HydroxybutyrateNAD oxidoreductase

2 hydroxybutyrate cotransport with proton

Aldehyde dehydrogenase 3 4 dihydroxyphenylacetaldehyde NAD

3,4-Dihydroxyphenylethyleneglycol NAD+ oxidoreductase

3,4-Dihydroxyphenylacetate:amet O-methyltransferase

34DHPLACOX_NADP

34DHPLACOX LPAREN NADP RPAREN

3,4-Dihydroxymandelaldehyde:NAD+ oxidoreductase

34DHXMANDACOX_NADP

3,4-Dihydroxymandelaldehyde:NADP+ oxidoreductase

3 Dehydrosphinganine reductase

3 hydroxyanthranilate 3 4 dioxygenase

3-Hydroxy-L-tyrosine carboxy-lyase

3-Hydroxykynurenamine decarboxy-lyase

3-Methoxy-4-hydroxyphenylacetaldehyde:NAD+ oxidoreductase

3-methyl-2-oxobutanoate mitochondrial transport via proton symport

3-Methyl-2-oxopentanoate mitochondrial transport via proton symport

3MOX4HOXPGALDOX

3-Methoxy-4-hydroxyphenylglycolaldehyde:NAD+ oxidoreductase

3MOX4HOXPGALDOX_NADP

3-Methoxy-4-hydroxyphenylglycolaldehyde:NADP+ oxidoreductase

3-Sulfino-L-alanine carboxy-lyase

Cysteinesulfinic acid oxidase

3-sulfino-alanine transaminase (irreversible)

3-sulfinopyruvate hydrolase (spotaneous reaction)

Aldehyde dehydrogenase 4 hydroxyphenylacetaldehyde NAD

4HOXPACDOX_NADP

4HOXPACDOX LPAREN NADP RPAREN

4-methyl-2-oxopentanoate mitochondrial transport via proton symport

4-Nitrophenol Sulfotransferase

4-Pyridoxal secretion

5ADTSTSTERONEGLCte

Glucuronidated compound transport

5ADTSTSTERONESULT

5alpha-Dihydrotestosterone sulfotransferase

5-Hydroxy-L-tryptophan decarboxy-lyase

5-Hydroxyindoleacetaldehyde:oxygen oxidoreductase

5-Hydroxyindoleacetaldehyde:NAD+ oxidoreductase

5-hydroxy-L-tryptophan secretion via secretory vesicle (ATP driven)

5-Hydroxykynurenamine decarboxy-lyase

Lactosylceramide 4-alpha-galactosyltransferase

L-aminoadipate-semialdehyde dehydrogenase (NADH)

L-arabinitol 4-dehydrogenase

Aminobutyraldehyde dehydrogenase

4 aminobutyrate reversible transport in via proton symport

4-aminobutyrate reversible transport in via proton symport (lysosome)

Acetoacetate transport via proton symport

Acetoacetate mitochondrial transport via H+ symport

Acetyl-CoA carboxylase

Acetone transport via proton symport

Acetone mitochondrial transport via proton symport

N-acetylgalactosamine kinase

N-acetylgalactosamine kinase (ITP)

N acetylglucosamine 6 phosphate synthase

N-acetylglucosamine kinase

Acetylcholine secretion via secretory vesicle (ATP driven)

N-acetylneuraminate transport into lysososme

Acetyl-CoA hydrolase

Acetate mitochondrial transport via proton symport

Acetate reversible transport via proton symport

Acetol monooxygenase

Acetone monooxygenase

Acylphosphatase

Adenosine deaminase

Deoxycytidine kinase

Adenosylmethionine decarboxylase

Adenosine kinase

Adenosine kinase

Adenosine kinase

ADPglucose diphosphatase

ADPmannose diphosphatase

ADPribose diphosphatase

Adrenaline secretion via secretory vesicle (ATP driven)

Adenylyl-selenate kinase

Adenylyl-sulfate kinase

Adenylosuccinate synthase

Alkyl acylglycerol phosphocholine transferase

Alkyl acyl glycerophosphoethanolamine desaturase

Alkyl acylglycerol phosphoethanolamine transferase

Alkyl glycerol phosphate reductase

Alkyl glycerol phosphate acyltransferase

DGTP:pyruvate 2-O-phosphotransferase, cytosol

AHANDROSTANGLCte

Glucuronidated compound transport

Phosphoribosylaminoimidazole carboxylase

Aldo-keto reductase family 1, member C1 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)

Aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)

Aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)

Aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)

Aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)

Transport of Alanylalanine by the apical PEPT1 amino acid transporters across the brush border cells of the enterocytes of the intestine and renal cells

L alanine reversible transport via proton symport

L-alanine reversible transport via proton symport (lysosome)

Alanine transport (Na, H coupled)

Transport of Alanine by y+LAT1 or y+LAT2 with co-transporter of h in small intestine and kidney

Alcohol dehydrogenase (methanol)

Alcohol dehydrogenase glycerol NADP

Alcohol dehydrogenase (D-1,2-propanediol)

Alcohol dehydrogenase (D-lactaldehyde)

Alcohol dehydrogenase (L-lactaldehyde)

Alcohol dehydrogenase (ethanol)

Alcohol dehydrogenase (ethanol, NADP)

Aldehyde dehydrogenase (phenylacetaldehyde, NADP)

Aldehyde dehydrogenase (phenylacetaldehyde, NAD)

Aldehyde dehydrogenase (indole-3-acetaldehyde, NAD)

Aldehyde dehydrogenase (pristanal, NAD)

Aldehyde dehydrogenase (acetaldehyde, NAD)

Aldehyde dehydrogenase (acetaldehyde, NADP)

Aldose reductase

Aldose reductase (methylglyoxal)

Aldose reductase (acetol)

Aminomuconate-semialdehyde dehydrogenase

N-acetyl-D-mannosamine kinase

2-aminomuconate reductase

Adenosine monophosphate deaminase

Glucuronidated compound transport

Ap4A hydrolase, asymmetrically

ATP:pantetheine 4'-phosphotransferase

Apocarboxylase formation

Arabinose reductase

1;2-dihydroxy-3-keto-5-methylthiopentene dioxygenase

Argininosuccinate synthase

Arginine mitochondrial transport via ornithine carrier

R group coenzyme a ligase

R group coenzyme a ligase

R group coenzyme a ligase

Ascorbic acid oxidase

Transport of L-Ascorbate by SVCT1 or SVCT2 transporter

Asparagine synthase (glutamine-hydrolysing)

Asparagine transport (Na, H coupled)

Aspartate 1-decarboxylase

Aspartate carbamoyltransferase

D-aspartate transport via Na, H symport and K antiport

Aspartate-glutamate mitochondrial shuttle

L-aspartate transport via Na, H symport and K antiport

V-type ATPase, H+ transporting, lysosomal

ATP maintenance requirement

Biotin acetyl CoA carboxylase ligase

Beta Alanine transport in via proton symport

B-alanine secretion via secretory vesicle (ATP driven)

Beta-Aminopropion aldehyde NAD+ oxidoreductase

Beta-D-Glucosyl-2-coumarinate glucohydrolase

GDPmannose:chitobiosyldiphosphodolichol beta-D-mannosyltransferase (CHO)

Betaine-aldehyde dehydrogenase

Betaine-aldehyde dehydrogenase

(R)-3-Hydroxybutanoate transport via H+ symport

(R)-3-Hydroxybutanoate mitochondrial transport via H+ symport

Bilirubin beta-diglucuronide transport MDR

Bilirubin monoglucuronide transport MDR

Nad(p)h biliverdin reductase

Nadh biliverdin reductase

Biomass function

BIOMASS_cho_producing

Biomass for a producing cell line

Holocarboxylase synthestase (biotin protein ligase)

Biotin reversible transport via proton symport, mitochondria

Biotin transport via sodium symport

Beta-ureidopropionase (D-3-amino-isobutanoate forming)

Butyrate mitochondrial transport via proton symport, reversible

Butyrate transport via proton symport, reversible

CMP-N-acetylneuraminate monooxygenase, NADH

CMP-N-acetylneuraminate monooxygenase, NADPH

CAMP transport (ATP-dependent)

Carnosine synthase

Transport of L-Carnosine by the apical PEPT1 amino acid transporters across the brush border cells of the enterocytes of the intestine and renal cells

NADH:cob(III)alamine oxidoreductase

Carbamoyl-phosphate synthase (glutamine-hydrolysing)

Carbonyl reductase [NADPH] 1

Carbonyl reductase [NADPH] 1

Phosphatidylinositol synthase (Homo sapiens)

Phosphatidate cytidylyltransferase

Choline phosphotransferase

Ethanolamine phosphotransferase

Ceramide kinase

Cys-Gly transport in via proton symport

CGMP transport (ATP-dependent)

Choline phosphate cytididyltransferase

ABC bile acid transporter

Steroid sulfotransferase

Cholesterol efflux (ATP depedent)

Cholesterol efflux (ATP depedent), golgi

Citrulline mitochondrial transport via proton antiport

Citrate reversible transport via symport

ATP Creatine kinase (c)

Cardiolipin synthase (cho)

Choline-phosphate cytidylyltransferase

Coproporphyrinogen oxidase (O2 required)

L-carnitine outward transport (H+ antiport)

Cytosine deaminase

CTP synthase (glutamine)

Vitamin D3 25-hydroxylase

Cysteamine oxygenase

Cysteine oxidase

Transport of L-Cysteine into the cell coupled with co-transport with Sodium and counter transport with proton by SNAT5 transporter.

Cytidine deaminase

ATP:cytidine 5'-phosphotransferase

Cytidine kinase (GTP)

Deoxyadenosine deaminase

Deoxyadenosine kinase

Diacylglycerol phosphate kinase (cho)

D-alanine transport via proton symport

D-alanine transport via proton symport (lysosome)

Dehydroascorbate reductase

Transport of docosapentenoylcoa into peroxisomes.

Deoxycytidine deaminase

Dehydrodolichol diphosphate phosphatase (CHO)

Dehydrodolichol reductase (CHO)

Palmitoyl-CoA desaturase (n-C16:0CoA -> n-C16:1CoA)

Fatty acyl-CoA desaturase (n-C18:2CoA -> n-C18:3CoA)

Stearoyl-CoA desaturase (n-C18:0CoA -> n-C18:1CoA)

Stearoyl-CoA desaturase (n-C18:0CoA -> n-C18:1CoA)

Stearoyl-CoA desaturase (n-C18:0CoA -> n-C18:1CoA)

Linoleoyl-CoA, hydrogen-donor:oxygen oxidoreductase

Fatty acyl-CoA desaturase (n-C20:3CoA -> n-C20:4CoA)

Fatty acyl-CoA desaturase (n-C20:4CoA -> n-C20:5CoA)

Fatty acyl-CoA desaturase (n-C24:5CoA -> n-C24:6CoA)

Deoxyguanosine kinase

Dehydro-L-gulonate decarboxylase

Dihydroxyacetone kinase

Dihydroceramide desaturase

Dehydroepiandrosterone sulfotransferase

Dihydrofolate reductase

Dihydrofolate reductase (NAD+)

Dihydropyrimidinase (5,6-dihydrouracil)

Dihydropyrimidinase (dihydrothymine)

6,7-dihydropteridine reductase

6,7-dihydropteridine reduction

Diamine transaminase

Inosine diphosphate phosphatase

2,3-diketo-5-methylthio-1-phosphopentane degradation reaction 2

D lactate transport via proton symport

D lactate transport mitochondrial

Dimethylarginine Dimethylaminohydrolase

Deamino-NAD+ nucleotidohydrolase

Dinucleosidetriphosphatase

Transport of behenoylcoa into peroxisomes

2,3-dioxo-L-gulonate:hydrogen peroxide oxireductase

2,3-dioxo-L-gulonate:hydrogen peroxide oxireductase

Dolichol kinase

Dopamine:amet O-methyltransferase

Dopaquinone isomerase 1

Dopamine Sulfotransferase

Dopamine secretion via secretory vesicle (ATP driven)

Dephospho-CoA kinase

Pyrophasphatase (dephospho-CoA)

Diphosphoglyceromutase

Deoxyribokinase

Dihydrosphingosine N-acyltransferase

Dihydrouracil dehydrogenase (NADP)

Dihydrothymin dehydrogenase (NADP)

Dihydrouracil dehydrogenase (NAD)

Deoxyuridine kinase (ATP:Deoxyuridine)

DUTP:cytidine 5'-phosphotransferase

DUTP diphosphatase

DUTP:uridine 5'-phosphotransferase

Trans-2-enoyl-CoA reductase (18:0) (NADPH)

Ethanolamine-phosphate cytidylyltransferase

epo_translation

Epo translation

17-beta-D-glucuronide transport (ATP-dependent)

Glucuronidated compound transport

ABC transporter

Estrogen sulfotransferase

Ethanolamine kinase

Ethanol monooxygenase

Fucose-1-phosphate guanylyltransferase

Fatty-acyl-ACP hydrolase

Fatty-acyl-ACP hydrolase

Fatty-acyl-ACP hydrolase

Fatty-acyl-ACP hydrolase

Fatty acyl-CoA peroxisomal transport via ABC system (16:0)

Fatty-acyl-ACP hydrolase

Fatty acyl ACP hydrolase

Fatty acyl ACP hydrolase

Fatty-acyl-ACP hydrolase

Fatty-acyl-ACP hydrolase

Fatty acyl ACP hydrolase

Fatty-acid-CoA thioesterase (octadecanoate)

Fatty-acid-CoA thioesterase (octadecenoate)

FAD diphosphatase

Fatty-acyl-CoA elongation (n-C18:3CoA)

Fatty-acyl-CoA elongation (n-C20:4CoA)

Fatty-acyl-CoA elongation (n-C20:4CoA)

Fatty-acyl-CoA elongation (n-C20:5CoA)

Fatty acid omega-hydroxylase

Fatty acid omega-hydroxylase

Fatty acid omega-hydroxylase

Formaldehyde dehydrogenase

FAOXOHMC10DC10c

Fatty acid omega oxidation(w-OHMC10-->DC10)c

Fatty acid biosynthesis (n-C10:0ACP)

Fatty-acid biosynthesis (n-C12:0ACP)

Fatty-acid biosynthesis (n-C14:0ACP)

Fatty-acid biosynthesis (n-C16:0ACP)

Fatty-acid biosynthesis (n-C18:0ACP)

Fatty acid biosynthesis (n-C8:0ACP), lumped reaction

Formyl coa hydrolase

Uptake of food iron by DMT1 transporter

Iron (II) transport

N Formyl L kynurenine amidohydrolase

FMN adenylyltransferase

Folate transport via proton simport

Folylpolyglutamate synthetase

Folylpolyglutamate synthetase

Folylpolyglutamate synthetase

Folylpolyglutamate synthetase (DHF)

Folylpolyglutamate synthetase (DHF)

Folylpolyglutamate synthetase (DHF)

Folylpolyglutamate synthetase (10fthf)

Folylpolyglutamate synthetase (10fthf)

Folylpolyglutamate synthetase (10fthf)

Formimidoyltransferase cyclodeaminase reversible

10-formyltetrahydrofolate:NADP+ oxidoreductase

Fumarylacetoacetase

Fumarylpyruvate hydrolase

Glycolipid 1,2-alpha-D-mannosyltransferase

Glycolipid 1,2-alpha-D-mannosyltransferase

Glycolipid 1,3-alpha-D-mannosyltransferase (CHO)

Glycolipid 1,6-alpha-D-mannosyltransferase (CHO)

Glycerol 3 phosphate dehydrogenase NAD

L-glutamate 5-semialdehyde dehydratase (spontaneous)

Glucose 6-phosphate dehydrogenase

GABA secretion via secretory vesicle (ATP driven)

Guanidinoacetate N-methyltransferase (c)

D-Galactose:NADP+ 1-oxidoreductase

Transport of D-Galactose from extracellular space to cytosol of mucosal cells in small intestine

D-galactose transport via proton symport

UTP-glucose-1-phosphate uridylyltransferase (irreversible)

Glyceraldehyde-3-phosphate dehydrogenase

Phosphoribosylglycinamide formyltransferase

Glucose-1,6-bisphosphate synthase

Glycolaldehyde dehydrogenase

ABC bile acid transporter

Glutathione-disulfide reductase

GDP-L-fucose synthase

Glycogenin self-glucosylation

Glycine hydroxymethyltransferase

ADP-dependent glucokinase

D-Glucuronolactone:NAD+ oxidoreductase

UDP-GlcNAc:N-acetyl-D-glucosaminyl diphosphodolichol N-acetyl-D-glucosaminyltransferase

Transport of D-glucose from extracellular space to cytosol of mucosal cells in small intestine

D-glucose transport in via proton symport

D-glucose transport in via proton symport

Glucuronate transport into lysososme

Glycogen synthase (ggn -> glygn1)

Glutamine synthetase

Glutamine transport (Na, H coupled)

Transport of Glutamine by y+LAT1 or y+LAT2 with co-transporter of h in small intestine and kidney

Glucuronolactone reductase

Gamma-glutamylcysteine synthetase

Glutamate Decarboxylase

Formimidoyltransferase cyclodeaminase

Amino acid transporter (glu-L), mitochondrial

Glutamate transport via Na, H symport and K antiport

L-glutamate secretion via secretory vesicle (ATP driven)

Glyoxylate oxidase

D-Glyceraldehyde dehydrogenase

Glycerate kinase

Glycerate kinase

Glycolate dehydrogenase (NADP)

Glycerol kinase

Transport of Glycylleucine by the apical PEPT1 amino acid transporters across the brush border cells of the enterocytes of the intestine and renal cells

Hydroxyacylglutathione hydrolase

Transport of Glycylphenylalanine by the apical PEPT1 amino acid transporters across the brush border cells of the enterocytes of the intestine and renal cells

Transport of Glycylproline by the apical PEPT1 amino acid transporters across the brush border cells of the enterocytes of the intestine and renal cells

Transport of Glycylsarcosine by the apical PEPT1 amino acid transporters across the brush border cells of the enterocytes of the intestine, renal cells and brain.

Transport of Glycine into the cell coupled with co-transport with Sodium and counter transport with proton by SNAT5 transporter.

Glycine reversible transport via proton symport

Glycine reversible transport via proton symport (lysosome)

Glycine secretion via secretory vesicle (ATP driven)

Glycine N-methyltransferase

Glycerophosphodiester phosphodiesterase (Glycerophosphocholine)

Glutathione oxidoreductase

Glutathione transport into mitochondria

Glutathione synthetase

GTP cyclohydrolase I

Guanine deaminase

L-gulonate 3-dehydrogenase

Gulonate dehydrogenase

Hydrogen peroxide synthesis (NADPH dependent)

Hyaluronan synthase

Hyaluronan synthase

HCO3 equilibration reaction

Hexokinase (D-glucose:ATP)

Hexokinase (D-glucosamine:ATP)

Hexokinase (D-mannose:ATP)

Hexokinase (D-fructose:ATP)

Homogentisateoxygen 1 2 oxidoreductase decyclizing

Histidine decarboxylase

Transport of L-Histidine by hPT3 or hPT4 peptide transporters.

Histidine mitochondrial transport via proton symport

Histamine secretion via secretory vesicle (ATP driven)

Histidine transport (Na, H coupled)

Transport of Histidine by y+LAT1 or y+LAT2 with co-transporter of h in small intestine and kidney

Hydroxymethylglutaryl CoA reductase

Hydroxymethylglutaryl CoA synthase

Hydroxylysine kinase

Heme oxygenase 1

L hydroxyproline reductase NADP

Trans-4-Hydroxy-L-proline:NAD+ 5-oxidoreductase Arginine and proline metabolism EC:1.5.1.2

Hydroxypyruvate decarboxylase

Hydroxypyruvate reductase (NADH)

Hydroxypyruvate reductase (NADH)

Hydroxypyruvate reductase (NADPH)

Testicular 17-beta-hydroxysteroid dehydrogenase

3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type I

3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type I

Proton transport, Golgi

H transporter, endoplasmic reticulum

H transporter, peroxisome

5-hydroxyisourate amidohydrolase

Hypoxanthine dehydrogenase

Iodide:hydrogen-peroxide oxidoreductase 2

Iodide:hydrogen-peroxide oxidoreductase

Iduronate transport into lysososme

Imidazole acetaldeyde dehydrogenase

IMP dehydrogenase

Myo-Inositol:oxygen oxidoreductase

Insosine kinase

Inositol transport in via proton symport

Inositol-tetrakisphosphate 1-kinase

Imidazolonepropionase

B-ketoacyl synthetase (palmitate, n-C16:0)

Ketohexokinase (D-xylulose)

Ketohexokinase (D-tagatose)

Potassium transport via proton antiport

Potassium transport out via proton antiport

Kynurenine 3 monooxygenase

D-lactaldehyde dehydrogenase

D-Lactaldehyde NAD+ oxidoreductase (glutathione-formylating)

D-Lactaldehyde:NAD+ 1-oxidoreductase

Lactaldehyde dehydrogenase

Lactaldehyde dehydrogenase

Lacaldehyde reductase (R-propane-1,2-diol forming)

Lacaldehyde reductase (S-propane-1,2-diol forming)

3-Sulfoalanine carboxy-lyase

D-lactate dehydrogenase

L-lactate dehydrogenase

Transport of Leucylglycine by the apical PEPT1 amino acid transporters across the brush border cells of the enterocytes of the intestine and renal cells

Transport of Leucylleucine by the apical PEPT1 amino acid transporters across the brush border cells of the enterocytes of the intestine and renal cells

Transport of Leucine by y+LAT1 or y+LAT2 with co-transporter of h in small intestine and kidney

L-Formylkynurenine hydrolase

Transport of lignocericyl coenzyme A from cytosol to peroxisome.

Lipoate transport via sodium symport

L lactate reversible transport via proton symport

L lactate transport mitochondrial

Lysophospholipase

L-Tryptophan decarboxy-lyase

Lysine mitochondrial transport via ornithine carrier

3-Methylimidazole acetaldehyde:NAD+ oxidoreductase

Mannose 1 phosphate guanylyltransferase

Mannose-1-phosphate guanylyltransferase (GDP)

Malonyl-CoA Decarboxylase cytoplasmic

2-methylcitrate synthase

3-mercaptolactate:cysteine reductase

3-Mercaptolactate:NAD+ oxidoreductase irreversible

3-mercaptopyruvate sulfurtransferase

Malate dehydrogenase

Melatonin:NADP oxidoreductase

Metanephrine secretion via secretory vesicle (ATP driven)

Methionine synthase

Transport of Methionine by y+LAT1 or y+LAT2 with co-transporter of h in small intestine and kidney

Mevalonate kinase atp

Inositol-1,3,4,5,6-pentakisphosphate 2-kinase

ATP:1D-myo-inositol-1,3,4-trisphosphate 6-phosphotransferase

Inositol-1,4,5-trisphosphate 3-kinase

Inositol-3,4,5,6-tetrakisphosphate 1-kinase

Phosphatidylinositol-4-phosphate 3-kinase

Methenyltetrahydrofolate cyclohydrolase

5,10-methylenetetrahydrofolate reductase (NADH)

5 10 methylenetetrahydrofolatereductase NADPH

N4 AcetylaminobutanalNAD oxidoreductase

Transport of Nicotinate

NAD diphosphatase

NAD nucleosidase

NADP nucleosidase

Nicotinate-mononucleotide adenylyltransferase

Bicarbonate transport (HCl/NaHCO3 exchange)

Bicarbonate transport (HCl/NaHCO3 exchange) (2 HCO3)

Na+/K+ exchanging ATPase

Sodium proton antiporter HNA is 11

Sodium proton antiporter (H:NA is 1:1)

Nucleoside diphosphatase ADP

Nucleoside diphosphatase GDP

Nucleoside-diphosphatase (dCDP)

Nucleoside diphosphatase UDP

Nucleoside-diphosphatase (dUDP)

Ammonia transport via proton antiport

Nicotinate-nucleotide diphosphorylase (carboxylating)

Noradrenaline N-methyltransferase

L-Arginine,NADPH:oxygen oxidoreductase (N-(omega)-hydroxyarginine-forming)

Nitric Oxide Synthase (NO forming)

Nucleotide phosphatase

Norepinephrine Sulfotransferase

Noradrenaline secretion via secretory vesicle (ATP driven)

Transport of nervonylcoa into peroxisomes

Nucleoside-triphosphatase (ITP)

Nucleoside triphosphate pyrophosphorylase (ditp)

Nucleoside triphosphate pyrophosphorylase (xtp)

Nucleoside triphosphate pyrophosphorylase (gtp)

Nucleoside triphosphate pyrophosphorylase (dctp)

Nucleoside triphosphate pyrophosphorylase (datp)

Nucleoside triphosphate pyrophosphorylase (dttp)

Nucleoside triphosphate pyrophosphorylase (itp)

Oxaloacetate decarboxylase

2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase

Orotidine-5'-phosphate decarboxylase

5-Oxoproline amidohydrolase (ATP-hydrolysing) (ir)

Ornithine Decarboxylase

Ornithine mitochondrial transport via proton antiport

Ornithine mitochondrial transport exchange with citruline

Cytochrome P450 2A6

Cytochrome P450 2C18

Cytochrome P450 2C19

Cytochrome P450 2C8

Cytochrome P450 2C9

Cytochrome P450 2C9

Cytochrome P450 2C9

Cytochrome P450 2C9

Cytochrome P450 2D6

Cytochrome P450 2E1

Cytochrome P450 2F1

Cytochrome P450 3A4

Cytochrome P450 3A5

Pyrroline-5-carboxylate reductase

Pyrroline-5-carboxylate reductase(nadh)

Platelet-activating factor acetylhydrolase

Phosphoadenylyl-sulfate reductase (thioredoxin)

Phosphatidylcholine flippase

Choline phosphatase

Picolinic acid decarboxylase

Phosphatidylcholine transporter

3',5'-cyclic-nucleotide phosphodiesterase

3',5'-cyclic-nucleotide phosphodiesterase

Phosphatidylethanolamine flippase

Phosphatidylethanolamine flippase

Phosphoethanolamine cytidyltransferase

Phosphofructokinase

6 phosphofructo 2 kinase

Phosphoglycerate dehydrogenase

6-phosphogluconolactonase

Phosphatidyl-CMP: glycerophosphate phosphatidyltransferase

Prostaglandin G/H synthase

Phenylalanine mitochondrial transport via proton symport

Transport of Phenylalanine by y+LAT1 or y+LAT2 with co-transporter of h in small intestine and kidney

L-Phenylalanine carboxy-lyase

Phylloquinone transport

Phosphatidylinositol 3,4-bisphosphate 5-kinase

Phosphatidylinositol 3-phosphate 4-kinase

Phosphatidylinositol 3-phosphate 5-kinase

Phosphatidylinositol 4,5-bisphosphate 3-kinase

Phosphatidylinositol 4,5-bisphosphate phospholipase C

Phosphatidylinositol 4-phosphate 3-kinase

Phosphatidylinositol 4-phosphate 5-kinase

Phosphatidylinositol 4-phosphate phospholipase C

Phosphatidylinositol-5-phosphate 3-kinase

Phosphatidylinositol-5-phosphate 4-kinase

Phosphatidylinositol N-acetylglucosaminyltransferase

Phosphatidylinositol 3-kinase

Phosphatidylinositol 4-kinase

Phosphatidylinositol 5-kinase

Phosphatidylinositol phospholipase C

Phosphate transporter mitochondrial

Phosphate mitochondrial transport via proton symport

Phospholipase A2

Phospholipase A2

5 diphosphoinositol 1 2 3 4 6 pentakisphosphate diphosphohydrolase

Diphosphoinositol 1 3 4 6 tetrakisphosphate diphosphohydrolase

Purine nucleoside phosphorylase

Pantothenate kinase

Pantothenate sodium symporter II

Inorganic diphosphatase

Inorganic triphosphatase

Porphobilinogen synthase

Phosphopantothenoylcysteine decarboxylase

Propane-1,2-diol:NADP+ 1-oxidoreductase

Phosphopantothenate-cysteine ligase

4'-Phosphopantothenate:L-cysteine ligase

Polyphosphate phosphohydrolase

Phosphoribosylglycinamide synthase

Phosphoribosylaminoimidazole synthase

Phosphoribosylaminoimidazolesuccinocarboxamide synthase

Phosphoribosylformylglycinamidine synthase

Steroid sulfotransferase

Transport of pristanoylcoa from cytosol to peroxisomes.

Proline oxidase L proline NAD

Proline dehydrogenase

D-proline reversible transport via proton symport

D-proline reversible transport via proton symport (lysosome)

Transport of Prolylglycine by the apical PEPT1 amino acid transporters across the brush border cells of the enterocytes of the intestine and renal cells

Prostaglandine E1 transport (ATP-dependent)

Prostaglandine E2 transport (ATP-dependent)

L proline reversible transport via proton symport

L-proline reversible transport via proton symport (lysosome)

Phosphoribosylpyrophosphate synthetase

Phosphatidylserine flippase

Phosphatidylserine flippase

Pantetheine-phosphate adenylyltransferase

Putrescine acetyltransferase

Pyridoxamine kinase

Pyridoxal kinase

Pyridoxine kinase

Pyruvate kinase

Pyruvate kinase(2)

Pyruvate kinase(3)

Pyruvate kinase(4)

Perillyl aldehyde:NAD+ oxidoreductase

Pyruvate transport in via proton symport

Pyruvate mitochondrial transport via proton symport

Pyruvate peroxisomal transport via proton symport

Quinolinate Synthase Eukaryotic

NADPH:CoA-glutathione oxidoreductase EC:1.8.1.9

Acetyl adenylate:CoA ligase (AMP-forming) Pyruvate metabolism EC:6.2.1.1

Oxalosuccinate:NADP+ oxidoreductase (decarboxylating) Citrate cycle (TCA cycle) EC:1.1.1.42

Acetate:CoA ligase (AMP-forming) Pyruvate metabolism EC:6.2.1.1

GTP 7,8-8,9-dihydrolase Folate biosynthesis EC:3.5.4.16

UTP:D-fructose-6-phosphate 1-phosphotransferase EC:2.7.1.11

L-Cysteine L-homocysteine-lyase (deaminating) Cysteine metabolism EC:4.4.1.1

L-Serine hydro-lyase (adding homocysteine) Glycine, serine and threonine metabolism EC:4.2.1.22

Propinol adenylate:CoA ligase (AMP-forming) Propanoate metabolism EC:6.2.1.17 EC:6.2.1.1

N-Formylanthranilate amidohydrolase Tryptophan metabolism EC:3.5.1.9

CMP-N-acetylneuraminate,ferrocytochrome-b5:oxygen oxidoreductase (N-acetyl-hydroxylating) Aminosugars metabolism EC:1.14.18.2

Cytidine monophospho-N-acetylneuraminic acid hydroxylase EC:1.14.18.2

DATP:pyruvate O2-phosphotransferase Purine metabolism EC:2.7.1.40

L-Histidine:beta-alanine ligase (AMP-forming) Alanine and aspartate metabolism / Histidine metabolism / beta-Alanine metabolism EC:6.3.2.11

Propanoate:CoA ligase (AMP-forming) Propanoate metabolism EC:6.2.1.1 EC:6.2.1.17

5,6-Dihydrothymine:NAD+ oxidoreductase Pyrimidine metabolism EC:1.3.1.1

Glycolysis / Glyconeogenesis EC:2.7.1.1

Glycolysis / Glyconeogenesis EC:2.7.1.1

Glycolysis / Glyconeogenesis EC:2.7.1.1

Glycolysis / Glyconeogenesis EC:2.7.1.1

Glycolysis / Glyconeogenesis EC:2.7.1.1

Glycolysis / Glyconeogenesis EC:2.7.1.1

Glycolysis / Glyconeogenesis EC:2.7.1.1

Glycolysis / Glyconeogenesis EC:2.7.1.1

Hypotaurine:NAD+ oxidoreductase Taurine and hypotaurine metabolism EC:1.8.1.3

NADPH:6,7-dihydropteridine oxidoreductase Folate biosynthesis EC:1.5.1.34

N-acetylneuraminate,ferrocytochrome-b5:oxygen oxidoreductase (N-acetyl-hydroxylating) Aminosugars metabolism EC:1.14.18.2

Tetrahydrobiopterin:NADP+ oxidoreductase Folate biosynthesis EC:1.1.1.153

ATP:Sedoheptulose 7-phosphate 1-phosphotransferase EC:2.7.1.11

UTP:Sedoheptulose 7-phosphate 1-phosphotransferase EC:2.7.1.11

Isocitrate:NADP+ oxidoreductase (decarboxylating) Citrate cycle (TCA cycle) EC:1.1.1.42

L-Histidine:4-aminobutanoate ligase (AMP-forming) Urea cycle and metabolism of amino groups EC:6.3.2.11

S-Adenosyl-L-methionine:ethanolamine-phosphate N-methyltransferase Glycerophospholipid metabolism EC:2.1.1.103

Gentisate aldehyde:NAD+ oxidoreductase Tyrosine metabolism EC:1.2.1.29

Aldehyde oxidase Tyrosine metabolism EC:1.2.3.1

N-((R)-Pantothenoyl)-L-cysteine carboxy-lyase Pantothenate and CoA biosynthesis EC:4.1.1.30

3-Mercaptopyruvate:cyanide sulfurtransferase Cysteine metabolism EC:2.8.1.2

CTP:D-Tagatose 6-phosphate 1-phosphotransferase Galactose metabolism EC:2.7.1.11

ITP:D-Tagatose 6-phosphate 1-phosphotransferase Galactose metabolism EC:2.7.1.11

(S)-Methylmalonate semialdehyde:NAD+ oxidoreductase Valine, leucine and isoleucine degradation EC:1.2.1.3

(S)-Methylmalonate semialdehyde:oxygen oxidoreductase Valine, leucine and isoleucine degradation EC:1.2.3.1

6-Lactoyl-5,6,7,8-tetrahydropterin:NADP+ 2-oxidoreductase Folate biosynthesis EC:1.1.1.220

ATP:pantothenate 4-phosphotransferase Pantothenate and CoA biosynthesis EC:2.7.1.33

2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl) dihydropteridine triphosphate 7,8-8,9-dihydrolase Folate biosynthesis EC:3.5.4.16

Alcohol dehydrogenase Bile acid biosynthesis EC:1.1.1.1

3alpha,7alpha-Dihydroxy-5beta-cholestane:NADP+ oxidoreductase (B-specific); 3alpha,7alpha-Dihydroxy-5beta-cholestane:NADP+ oxidoreductase Bile acid biosynthesis EC:1.1.1.50

3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane:NADP+ oxidoreductase (B-specific); 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane:NADP+ oxidoreductase Bile acid biosynthesis EC:1.1.1.50

Formamidopyrimidine nucleoside triphosphate 7,8-8,9-dihydrolase Folate biosynthesis EC:3.5.4.16

GTP 7,8-8,9-dihydrolase Folate biosynthesis EC:3.5.4.16

GDP-L-fucose:NADP+ 4-oxidoreductase (3,5-epimerizing) Fructose and mannose metabolism EC:1.1.1.271

Xylitol:NAD oxidoreductase Pentose and glucuronate interconversions EC:1.1.1.15

S-Adenosyl-L-methionine:methylethanolamine phosphate N-methyltransferase Glycerophospholipid metabolism EC:2.1.1.103

Spontaneous reaction

Ribitol:NAD+ 2-oxidoreductase Pentose and glucuronate interconversions EC:1.1.1.56

Virtual reaction/potential definition

ATP-binding Cassette (ABC) TCDB:3.A.1.208.2

ATP-binding Cassette (ABC) TCDB:3.A.1.201.2

ATP-binding Cassette (ABC) TCDB:3.A.1.201.2

TCDB:2.A.1.13.5 TCDB:2.A.1.13.1

Active transport

S-(hydroxymethyl)glutathione dehydrogenase Methane metabolism EC:1.1.1.284

Guanosine aminohydrolase EC:3.5.4.15

TCDB:2.A.1.13.5 TCDB:2.A.1.13.1

Transport reaction

Hexadecanal:NADP+ delta2-oxidoreductase EC:1.3.1.27

ATP-binding Cassette (ABC) TCDB:3.A.1.211.1

ATP-binding Cassette (ABC) TCDB:3.A.1.211.1

ATP-binding Cassette (ABC) TCDB:3.A.1.211.1

ATP-binding Cassette (ABC) TCDB:3.A.1.211.1

ATP-binding Cassette (ABC) TCDB:3.A.1.211.1

ATP-binding Cassette (ABC) TCDB:3.A.1.211.1

ATP-binding Cassette (ABC) TCDB:3.A.1.211.1

ATP-binding Cassette (ABC) TCDB:3.A.1.211.1

ATP-binding Cassette (ABC) TCDB:3.A.1.211.1

ATP-binding Cassette (ABC) TCDB:3.A.1.211.1

ATP-binding Cassette (ABC) TCDB:3.A.1.211.1

ATP-binding Cassette (ABC) TCDB:3.A.1.211.1

ATP-binding Cassette (ABC) TCDB:3.A.1.211.1

ATP-binding Cassette (ABC) TCDB:3.A.1.211.1

ATP-binding Cassette (ABC) TCDB:3.A.1.211.1

ATP-binding Cassette (ABC) TCDB:3.A.1.208.15

ATP-binding Cassette (ABC) TCDB:3.A.1.208.15

ATP-binding Cassette (ABC) TCDB:3.A.1.208.15

ATP-binding Cassette (ABC) TCDB:3.A.1.208.15

ATP-binding Cassette (ABC) TCDB:3.A.1.208.7

Zinc (Zn2+)-Iron (Fe2+) Permease (ZIP), TCDB:2.A.55.2.3

Mitochondrial Carrier (MC) TCDB:2.A.29.7.2

Mitochondrial Carrier (MC) TCDB:2.A.29.7.2

Mitochondrial Carrier (MC) TCDB:2.A.29.7.2

Mitochondrial Carrier (MC) TCDB:2.A.29.7.2

Mitochondrial Carrier (MC) TCDB:2.A.29.7.2

Mitochondrial Carrier (MC) TCDB:2.A.29.7.2

Mitochondrial Carrier (MC) TCDB:2.A.29.7.2

Mitochondrial Carrier (MC) TCDB:2.A.29.7.2

Mitochondrial Carrier (MC) TCDB:2.A.29.7.2

Mitochondrial Carrier (MC) TCDB:2.A.29.7.2

Mitochondrial Carrier (MC) TCDB:2.A.29.7.2

Mitochondrial Carrier (MC) TCDB:2.A.29.19.1

Mitochondrial Carrier (MC) TCDB:2.A.29.19.1

Mitochondrial Carrier (MC) TCDB:2.A.29.19.1

Mitochondrial Carrier (MC) TCDB:2.A.29.19.1

Mitochondrial Carrier (MC) TCDB:2.A.29.19.1

Mitochondrial Carrier (MC) TCDB:2.A.29.19.1

Mitochondrial Carrier (MC) TCDB:2.A.29.19.1

Mitochondrial Carrier (MC) TCDB:2.A.29.19.1

Mitochondrial Carrier (MC) TCDB:2.A.29.19.1

Mitochondrial Carrier (MC) TCDB:2.A.29.19.1

Mitochondrial Carrier (MC) TCDB:2.A.29.19.1

Mitochondrial Carrier (MC) TCDB:2.A.29.19.1

Mitochondrial Carrier (MC) TCDB:2.A.29.19.1

Mitochondrial Carrier (MC) TCDB:2.A.29.19.1

Mitochondrial Carrier (MC) TCDB:2.A.29.19.1

Mitochondrial Carrier (MC) TCDB:2.A.29.19.1

Mitochondrial Carrier (MC) TCDB:2.A.29.19.1

Mitochondrial Carrier (MC) TCDB:2.A.29.19.1

Mitochondrial Carrier (MC) TCDB:2.A.29.19.1

ATP-binding Cassette (ABC) TCDB:3.A.1.203.3

ATP-binding Cassette (ABC) TCDB:3.A.1.203.3

ATP-binding Cassette (ABC) TCDB:3.A.1.203.3

ATP-binding Cassette (ABC) TCDB:3.A.1.203.3

ATP-binding Cassette (ABC) TCDB:3.A.1.203.3

ATP-binding Cassette (ABC) TCDB:3.A.1.203.3

ATP-binding Cassette (ABC) TCDB:3.A.1.208.8

Major Facilitator(MFS) TCDB:2.A.1.13.1

ATP-binding Cassette (ABC) TCDB:3.A.1.203.1

ATP-binding Cassette (ABC) TCDB:3.A.1.203.1

Retinal dehydrogenase

Retinal dehydrogenase (NADPH)

Retinal dehydrogenase

Retinal dehydrogenase (NADPH)

Retinoic acid hydroxylation (P450)

Riboflavin kinase

D-ribulokinase (D-ribulose)

Retinol dehydrogenase (all-trans)

Retinol dehydrogenase (all-trans,NADPH)

Retinol dehydrogenase (9-cis,NADH)

Retinol dehydrogenase (9-cis,NADPH)

Retinol dehydrogenase (11-cis,NADH)

Retinol dehydrogenase (11-cis,NADPH)

Retinol dehydrogenase (13-cis,NADH)

Palmitoyl Coenzyme A Hydrolase

Palmitoyl Coenzyme A Hydrolase

Steryl-Sulfatase

Steryl-Sulfatase

Aldehyde Reductase

Thymidine Kinase

Quinine 3-Monooxygenase

Catechol O-Methyltransferase

Quinine 3-Monooxygenase

Alcohol Dehydrogenase

Palmitoyl Coenzyme A Hydrolase

Palmitoyl Coenzyme A Hydrolase

Bile Acid-CoA:Amino Acid N-Acyltransferase

Deoxyhypusine Synthase

Aromatic-L-Amino-Acid Decarboxylase

Catechol O-Methyltransferase

Catechol O-Methyltransferase

Catechol O-Methyltransferase

3Alpha-Hydroxysteroid 3-Dehydrogenase (Si-Specific)

Steroid 21-Monooxygenase

Unspecific Monooxygenase

Catechol O-Methyltransferase

7-Dehydrocholesterol Reductase

NADPH:Quinone Reductase

Catechol O-Methyltransferase

17Beta-Estradiol 17-Dehydrogenase

Carbonyl Reductase (NADPH)

Aldehyde Dehydrogenase (NAD+)

Unspecific Monooxygenase

Arachidonate 5-Lipoxygenase

3Alpha-Hydroxysteroid 3-Dehydrogenase (Si-Specific)

Carbonyl Reductase (NADPH)

Carbonyl Reductase (NADPH)

Leukotriene-B4 20-Monooxygenase

Leukotriene-B4 20-Monooxygenase

Leukotriene-B4 20-Monooxygenase

Carbonyl Reductase (NADPH)

Carbonyl Reductase (NADPH)

Carbonyl Reductase (NADPH)

Retinyl ester hydrolase (9-cis)

Retinyl ester hydrolase (11-cis)

Riboflavin transport (ATP dependent)

Riboflavin transport out (ATP dependent)

Ribose transport in via proton symporter

Ribosylnicotinamide kinase

Sulfate adenylyltransferase

S-Adenosyl-L-methionine:catechol O-methyltransferase

S-Adenosyl-L-methionine:catechol O-methyltransferase

S-Adenosyl-L-methionine:histamine N-tele-methyltransferase

D sorbitol dehydrogenase D fructose producing

D sorbitol reductase

Transport of phytanoylcoa from cytosol to peroxisomes.

Selenate adenylyltransferase

Selenocysteine lyase

Selenocysteine lyase

Selenophosphate synthase

Serine C palmitoyltransferase

L serine reversible transport via proton symport

Serine transport (Na, H coupled)

Formation of sulfocysteine

S-Formylglutathione hydralase

Sphingolipid long chain base kinase sphinganine

L-sulfolactate dehydrogenase (NAD+)

Sphingomyelinase

Sphingomyelin phosphodiesterase

Sphingosine kinase

Spermidine acetyltransferase

Spermidine acetyltransferase (N8)

Spermidine synthase

Superoxide dismutase

Sepiapterin reductase

Spermine synthase

Acetyl-CoA:aralkylamine N-acetyltransferase

S-Adenosyl-L-methionine:amine N-methyltransferase (srtn)

Transport of Stearoyl-CoA from cytosol to peroxisomes

Transport of stearidonylcoa into peroxisomes.

Steryl-sulfatase

Steryl-sulfatase

Steryl-sulfatase

Steryl-sulfatase

Sulfite oxidase

Transport of taurine into the intestinal cells by PAT1

ABC bile acid transporter

Thiamin pyrophosphatase

NAD(P) transhydrogenase

Thiamine exit from the neterocytes

Thiamine transport in via proton symport, mitochondrial

Thiamine transport in via proton antiport

Thiamine-triphosphatase

L-threonine dehydrogenase

Thyroid peroxidase

4-trimethylaminobutyraldehyde dehydrogenase

Thymidine kinase (ATP:thymidine)

Thiamine diphosphokinase

Thioredoxin reductase (NADPH)

Thioredoxin (ubiquinone 10) reductase (NADPH)

Thioredoxin (ubiquinone 10) reductase (NADH)

Triiodothyronine Sulfotransferase

TSTSTERONEGLCte

Glucuronidated compound transport

Testosterone sulfotransferase

Tyramine Sulfotransferase

L-Tyrosine carboxy-lyase

UDP-N-acetyl-D-glucosamine 2-epimerase (Hydrolysis)

UDP-N-acetylgalactosamine diphosphorylase

UDP-N-acetylglucosamine diphosphorylase

UDPglucuronate uridine-monophosphohydrolase

UDPglucose 6-dehydrogenase

UDP-glucuronate glucuronohydrolase

UDP-glucose glucophosphohydrolase

Ceramide glucosyltransferase

2-keto-4-methylthiobutyrate transamination

Uroporphyrinogen decarboxylase (uroporphyrinogen III)

B-ureidopropionase

Uridine kinase ATPUridine

Uridine kinase (GTP:Uridine)

Efflux of alpha-Tocopherol into the lyphatics in chylomicrons

Xanthine dehydrogenase

D-xylose:NADP+ 1-oxidoreductase

Xylose reductase

Xylitol dehydrogenase D xyulose forming

Xylulose reductase

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Universal metabolite ?

h

External database links

InChI Key: GPRLSGONYQIRFK-UHFFFAOYSA-N
Reactome Compound: 1132304, 113529, 1470067, 156540, 163953, 193465, 194688, 2000349, 2872447, 351626, 372511, 374900, 425969, 425978, 425999, 427899, 428040, 428548, 5668577, 70106, 74722
SEED Compound: cpd00067
CHEBI: CHEBI:10744, CHEBI:13357, CHEBI:15378, CHEBI:5584
Human Metabolome Database: HMDB59597
MetaNetX (MNX) Chemical: MNXM1
KEGG Compound: C00080
BioCyc: META:PROTON

Provided by MetaNetX (CC BY 4.0)

Old identifiers

h[c]

h in other models