Reaction: HSD17B1

Descriptive name:

Testicular 17-beta-hydroxysteroid dehydrogenase

Model:

iCHOv1

Reaction:

h_c + nadph_c + estrone_c ⇌ nadp_c + estradiol_c

Metabolites:

Stoichiometry
BiGG ID
Name
-1.0
h_c
H+
1.0
nadp_c
Nicotinamide adenine dinucleotide phosphate
-1.0
nadph_c
Nicotinamide adenine dinucleotide phosphate - reduced
1.0
estradiol_c
Estradiol c
-1.0
estrone_c
Estrone cytosol

Default bounds:

(-1000.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

STEROID METABOLISM

Gene Reaction Rule:

100750866 or 100766230

Genes:

100750866 (Hsd17b1)
100766230 (Hsd17b8)

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Universal reaction ?

External database links

Provided by MetaNetX (CC BY 4.0)

Old identifiers

    HSD17B1

HSD17B1 in other models