Reaction: HSD17B1

Descriptive name:

Testicular 17-beta-hydroxysteroid dehydrogenase

Model:

iMM1415

Reaction:

h_c + nadph_c + estrone_c ⇌ nadp_c + estradiol_c

Metabolites:

Stoichiometry
BiGG ID
Name
-1.0
h_c
H+
1.0
nadp_c
Nicotinamide adenine dinucleotide phosphate
-1.0
nadph_c
Nicotinamide adenine dinucleotide phosphate - reduced
1.0
estradiol_c
Estradiol c
-1.0
estrone_c
Estrone cytosol

Default bounds:

(-100000.0, 100000.0)

Objective coefficient:

0.0

Subsystem:

Steroid Metabolism

Gene Reaction Rule:

15485 or 14979

Genes:

15485 (Hsd17b1)
14979 (H2-Ke6)

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Universal reaction ?

External database links

Provided by MetaNetX (CC BY 4.0)

Old identifiers

    HSD17B1

HSD17B1 in other models