Reaction: PDE4


Descriptive name:

3',5'-cyclic-nucleotide phosphodiesterase

Model:

iCHOv1

Reaction:

35cgmp_c + h2o_c → gmp_c + h_c

Metabolites:


Default bounds:

(0.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

NUCLEOTIDE INTERCONVERSION

Gene Reaction Rule:

100689193 or 100750420 or 100751551 or 100755315 or 100756511 or 100765436 or 100762910 or 100774584 or 100774969 or 100775064 or (((100766007 and 100762641) or 100752813) and 100764811 and 100762580)

Genes:

100689193 (Pde1b)
100751551 (Pde10a)
100752813 (Pde6c)
100755315 (Pde5a)
100756511 (Pde11a)
100750420 (Pde2a)
100764811 (Pde6g)
100765436 (Pde9a)
100762580 (Pde6d)
100762641 (Pde6a)
100766007 (Pde6b)
100774584 (Pde3a)
100762910 (Pde1a)
100774969 (Pde1c)
100775064 (Pde3b)


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