Reaction: PDE4

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Descriptive name:

3',5'-cyclic-nucleotide phosphodiesterase

Model:

iAT_PLT_636

Reaction:

35cgmp_c + h2o_c → gmp_c + h_c

Metabolites:

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Default bounds:

(0.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Nucleotides

Gene Reaction Rule:

(5145 and 5146 and 5147 and 5158 and 5148) or (5145 and 5158 and 5149) or 5152 or 5153 or 5148 or 8654 or 5136 or 5137 or 5138 or 5139 or 5140 or 5146 or 5147 or 50940 or 10846

Genes:

5136 (PDE1A)
5146 (PDE6C)
5138 (PDE2A)
5145 (PDE6A)
5149 (PDE6H)
5158 (PDE6B)
5152 (PDE9A)
5147 (PDE6D)
5140 (PDE3B)
10846 (PDE10A)
5137 (PDE1C)
8654 (PDE5A)
5139 (PDE3A)
5148 (PDE6G)
50940 (PDE11A)
5153 (PDE1B)

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