Reaction: PDE4

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Descriptive name:

3',5'-cyclic-nucleotide phosphodiesterase

Model:

iMM1415

Reaction:

35cgmp_c + h2o_c → gmp_c + h_c

Metabolites:

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Default bounds:

(0.0, 100000.0)

Objective coefficient:

0.0

Subsystem:

Nucleotides

Gene Reaction Rule:

54611 or 110855 or 242202 or 18573 or 241489 or 242202 or 23984 or (225600 and 18587 and 78600) or 18576 or 18575 or 18573 or 207728 or 18574 or 242202 or 18576 or (225600 and 110855 and 18582 and 18587 and 18588)

Genes:

18574 (Pde1b)
18575 (Pde1c)
18573 (Pde1a)
23984 (Pde10a)
18576 (Pde3b)
207728 (Pde2a)
54611 (Pde3a)
241489 (Pde11a)
225600 (Pde6a)
242202 (Pde5a)
18588 (Pde6g)
78600 (Pde6h)
110855 (Pde6c)
18587 (Pde6b)
18582 (Pde6d)

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