BiGG Models

Metabolite: h_m

Descriptive name:

H+

Model:

Formula:

H

Charge:

1

Compartment:

m - mitochondria

Reactions:

BiGG ID

Name

1a_24_25VITD2Hm

1-alpha-Vitamin D-24,25-hydroxylase (D2)

1a_24_25VITD3Hm

1-alpha-Vitamin D-24,25-hydroxylase (D3)

1-alpha,24R,25-Vitamin D-hydroxylase (D2)

1-alpha,24R,25-Vitamin D-hydroxylase (D3)

24R-Vitamin D-25-hydroxylase (D2)

24R-Vitamin D-25-hydroxylase (D3)

1-alpha-Vitamin D-25-hydroxylase (D2)

1-alpha-Vitamin D-25-hydroxylase (D3)

3 4 hydroxyphenyl lactate formation

Hydroxylation of 3-Decaprenyl-4-hydroxybenzoate (NADH)

Hydroxylation of 3-Decaprenyl-4-hydroxybenzoate (NADPH)

3-hydroxyisobutyryl-CoA hydrolase, mitochondrial

3-methyl-2-oxobutanoate mitochondrial transport via proton symport

3-Methyl-2-oxopentanoate mitochondrial transport via proton symport

3-sulfino-alanine transaminase (irreversible), mitochondrial

3-sulfinopyruvate hydrolase (spotaneous reaction), mitochondrial

4 hydroxybenzoyl CoA formation

4 hydroxybenzoate formation

L 4 hydroxyglutamate semialdehyde dehydrogenase mitochondrial

4-methyl-2-oxopentanoate mitochondrial transport via proton symport

5-Hydroxyindoleacetaldehyde:NAD+ oxidoreductase (mito)

L-aminoadipate-semialdehyde dehydrogenase (NADH), mitochondrial

4-Aminobutyraldehyde:NAD+ oxidoreductase

Aminobutyraldehyde dehydrogenase mitochondrial

Acetoacetate mitochondrial transport via H+ symport

Acetyl Coa carboxylase mitochondrial

Acetone mitochondrial transport via proton symport

N acteylglutamate synthase mitochondrial

Acetyl CoA hydrolase mitochondrial irreversible

Trans-2-enoyl-CoA reductase (NADPH) (C12:0)

Acetate mitochondrial transport via proton symport

Acetoacetate decarboxylation (irreversible), mitochondrial

Adenosine kinase, mitochondria

ADPribose diphosphatase (mitochondrial)

N acetyl g glutamyl phosphate reductase irreversible mitochondrial

5 aminolevulinate synthase

Aldehyde dehydrogenase indole 3 acetaldehyde NAD mitochondrial

Aldehyde dehydrogenase acetylaldehyde NAD mitochondrial

L-2-amino-3-oxobutanoate decarboxylation, mitochondrial (spontaneous)

Apocarboxylase formation, mitochondrial

Arginine decarboxylase, mitochondrial

Arginine mitochondrial transport via ornithine carrier

R group artificial flux (C18:3, n-3)

R group artificial flux

R group artificial flux

R group artificial flux

R group artificial flux

R group artificial flux

R group artificial flux

R group artificial flux

R group artificial flux

R group artificial flux

R group artificial flux

R group artificial flux

R group artificial flux

R group artificial flux

R group artificial flux

R group artificial flux

Aspartate-glutamate mitochondrial shuttle

Aspartate N-acetyltransferase, mitochondrial

ATP synthase (four protons for one ATP)

Biotin-[acetyl-CoA-carboxylase] ligase, mitochondrial

Beta-Aminopropion aldehyde:NAD+ oxidoreductase (m)

3-Hydroxybutanoate:NAD+ oxidoreductase, mitochondria

Betaine-aldehyde dehydrogenase, mitochondrial

(R)-3-Hydroxybutanoate mitochondrial transport via H+ symport

Holocarboxylase synthestase (biotin protein ligase), mitochondrial

Biotin reversible transport via proton symport, mitochondria

Butyrate mitochondrial transport via proton symport, reversible

Cob(I)alamin adenosyltransferase, mitochondrial

Carbamoyl-phosphate synthase (ammonia) (mitochondria

Phosphatidate cytidylyltransferase

Citrulline mitochondrial transport via proton antiport

ATP Creatine kinase

Methyltransferase COQ3

Ubiquinone biosynthesis methyltransferase COQ5

Ubiquinone biosynthesis COQ7

Citrate synthase

Cyanide sulfurtransferase, mitochondrial

Cytochrome c oxidase, mitochondrial Complex IV

Cytochrome c oxidase, mitochondrial Complex IV

Ubiquinol-10 cytochrome c reductase, Complex III

Cytidine kinase (ATP), mitochondrial

DATP diphosphatase, mitochondrial

Deoxycytidine kinase, mitochondrial (ATP)

DCTP diphosphatase, mitochondrial

Deoxyguanosine kinase

Dihydroxydecaprenylbenzoate methyltransferase

Dihydrofolate reductase mitochondrial

D lactate transport mitochondrial

Dephospho CoA kinase mitochondrial

3-Decaprenyl-4-hydroxy-5-methoxybenzoate decarboxylation

DTTP diphosphatase, mitochondrial

Deoxyuridine kinase (ATP:Deoxyuridine), mitochondrial

DUTP diphosphatase

Beta oxidation of long chain fatty acid

Beta oxidation fatty acid

Beta oxidation of long chain fatty acid (odd chain)

Beta oxidation of long chain fatty acid

Beta oxidation of long chain fatty acid

Beta oxidation fatty acid

Beta oxidation fatty acid

Beta oxidation fatty acid

FAOXC122_3E_6Em

Beta oxidation of fatty acid

FAOXC122_3Z_6Zm

Beta oxidation of long chain fatty acid

FAOXC123_3Z_6Z_9Zm

Beta oxidation of fatty acid

Beta oxidation of long chain fatty acid (odd chain)

Beta oxidation of long chain fatty acid

Beta oxidation fatty acid

Beta oxidation fatty acid

Beta oxidation fatty acid

FAOXC142_5E_8Em

Beta oxidation of fatty acid

FAOXC142_5Z_8Zm

Beta oxidation of long chain fatty acid

FAOXC143_5Z_8Z_11Zm

Beta oxidation of fatty acid

Beta oxidation of long chain fatty acid (odd chain)

Beta oxidation of long chain fatty acid

Beta oxidation fatty acid

Beta oxidation fatty acid

Beta oxidation fatty acid

Beta oxidation fatty acid

Beta oxidation fatty acid

FAOXC162_7E_10Em

Beta oxidation of fatty acid

FAOXC162_7Z_10Zm

Beta oxidation of fatty acid

FAOXC163_7Z_10Z_13Zm

Beta oxidation of fatty acid

Beta oxidation of long chain fatty acid (odd chain)

Beta oxidation of long chain fatty acid

Beta oxidation fatty acid

Beta oxidation fatty acid

Beta oxidation fatty acid

FAOXC182_9E_12Em

Beta oxidation of fatty acid

FAOXC182_9Z_12Zm

Beta oxidation of fatty acid

FAOXC183_6Z_9Z_12Zm

Beta oxidation of long chain fatty acid

FAOXC183_9Z_12Z_15Zm

Beta oxidation of fatty acid

FAOXC184_3Z_6Z_9Z_12Zm

Beta oxidation of long chain fatty acid

FAOXC184_6Z_9Z_12Z_15Zm

Beta oxidation of fatty acid

FAOXC185_3Z_6Z_9Z_12Z_15Zm

Beta oxidation of fatty acid

Beta oxidation of long chain fatty acid

Beta oxidation of fatty acid

Beta oxidation fatty acid

FAOXC204_5Z_8Z_11Z_14Zm

Beta oxidation of long chain fatty acid

FAOXC205_5Z_8Z_11Z_14Z_17Zm

Beta oxidation of fatty acid

Beta oxidation of long chain fatty acid

Beta oxidation of med/long chain fatty acid

Beta oxidation of long chain fatty acid (odd chain)

Beta oxidation of med/long chain fatty acid

Beta oxidation of fatty acid

Beta oxidation of long chain fatty acid (odd chain)

Beta oxidation of med/long chain fatty acid

Beta oxidation of fatty acid

Beta oxidation of long chain fatty acid (odd chain)

Fatty acyl-coa synthase (n-C8:0ACP) mitochondrial, lumped reaction

Ferrochelatase mitochondrial

Iron (II) transport

Folylpolyglutamate synthetase, mitochondrial

Folylpolyglutamate synthetase, mitochondrial

Folylpolyglutamate synthetase (DHF), mitochondrial

Folylpolyglutamate synthetase (DHF), mitochondrial

Folylpolyglutamate synthetase (DHF), mitochondrial

Folylpolyglutamate synthetase (10fthf), mitochondrial

Folylpolyglutamate synthetase (10fthf), mitochondrial

Folylpolyglutamate synthetase (10fthf), mitochondrial

Folylpolyglutamate synthetase, mitochondrial

L glutamate 5 semialdehyde dehydratase reversible mitochondrial

Glutamate-5-semialdehyde dehydrogenase, mitochondria

Glycolaldehyde dehydrogenase, mitochondrial

Glycine cleavage complex lipoamide mitochondrial

Glycine cleavage complex lipoamide mitochondrial

Glycine cleavage complex lipoylprotein mitochondrial

Glycine cleavage complex lipoylprotein mitochondrial

Glutamate dehydrogenase, mitochondria

Glutathione-disulfide reductase, mitochondria

Glycine hydroxymethyltransferase, mitochondrial

D-Glucuronolactone:NAD+ oxidoreductase, mitochondrial

Glutamate dehydrogenase (NADP), mitochondrial

Amino acid transporter (glu-L), mitochondrial

Glutaryl-CoA dehydrogenase (mitochondria)

Glycolate dehydrogenase (NADP), mitochondrial

Glycerol kinase

Hydroxyacylglutathione hydrolase mitochondrial

Guanosine kinase (mitochondrial)

Glutathione oxidoreductase

3-Hydroxybutanoyl-CoA:NAD+ oxidoreductase, mitochondria

(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA:NAD+ oxidoreductase

HCO3 equilibration reaction

3-hydroxyisobutyrate dehydrogenase, mitochondrial

Histidine mitochondrial transport via proton symport

Hydroxymethylglutaryl CoA synthase mitochondrial

L hydroxyproline dehydrogenase NAD mitochondrial

L hydroxyproline dehydrogenase NADP mitochondrial

Hydroxypyruvate decarboxylase, mitochondria

Uncoupling protein

Imidazole acetaldeyde dehydrogenase (mito)

Insosine kinase, mitochondrial

Lactaldehyde dehydrogenase, mitochondrial

Lactaldehyde dehydrogenase, mitochondrial

L-lactate dehydrogenase, mitochondria

L lactate transport mitochondrial

Lysine mitochondrial transport via ornithine carrier

Methylcrotonoyl-CoA carboxylase, mitochondrial

Malonyl-CoA Decarboxylase, mitochondrial

Malate dehydrogenase mitochondrial

Methylmalonyl-CoA decarboxylase, mitochondrial

Malonate-semialdehyde dehydrogenase (acetylating), mitochondrial

Methenyltetrahydrifikate cyclohydrolase mitochondrial

N4-Acetylaminobutanal:NAD+ oxidoreductase (m)

NADH dehydrogenase, mitochondrial

Nicotinamide nucleotide adenylyltransferase mitochondrial

Nicotinate nucleotide adenylyltransferase mitochondrial

Ornithine carbamoyltransferase, irreversible

Ornithine mitochondrial transport via proton antiport

Ornithine mitochondrial transport exchange with citruline

Cytochrome P450 11A1, mitochondrial [Precursor]

Steroid 11-beta-hydroxylase

Steroid 11-beta-hydroxylase

Steroid 11-beta-hydroxylase

5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase

5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase

5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase

5-beta-cytochrome P450, family 27, subfamily A, polypeptide 1

5-beta-cytochrome P450, family 27, subfamily A, polypeptide 1

Cytochrome P450 27

Cholesterol monooxygenase

1 pyrroline 5 carboxylate dehydrogenase mitochondrial

Pyrroline-5-carboxylate reductase, mitochondria

Pyrroline-5-carboxylate reductase (m)

Choline phosphatase

Pyruvate carboxylase

Phosphatidylethanolamine N-methyltransferase

Glycine N-phenylacetyltransferase

L 1 pyrroline 3 hydroxy 5 carboxylate dehydrogenase

L 1 Pyrroline 3 hydroxy 5 carboxylate spontaneous conversion to L 4 Hydroxyglutamate semialdehyde mitochondrial

Phenylalanine mitochondrial transport via proton symport

Phosphate transporter mitochondrial

Phosphate mitochondrial transport via proton symport

Pantothenate kinase (mitochondrial)

Inorganic triphosphatase, mitochondrial

Inorganic diphosphatase

Propionyl-CoA carboxylase, mitochondrial

Proline oxidase NAD mitochondrial

Proline dehydrogenase (m)

Phosphatidylserine decarboxylase

Panthetheine phosphate adenylyltransferase

Perillyl aldehyde:NAD+ oxidoreductase (m)

Pyruvate mitochondrial transport via proton symport

L-Glutamate 5-semialdehyde:NAD+ oxidoreductase Arginine and proline metabolism EC:1.5.1.12

Oxalosuccinate:NADP+ oxidoreductase (decarboxylating) Citrate cycle (TCA cycle) EC:1.1.1.42

L-threonine 3-dehydrogenase, mitochondrial

2-oxoglutarate dehydrogenase E1 component Citrate cycle (TCA cycle) EC:1.2.4.2

Succinate-semialdehyde:NADP+ oxidoreductase Glutamate metabolism / Tyrosine metabolism / Butanoate metabolism EC:1.2.1.16

Propinol adenylate:CoA ligase (AMP-forming) Propanoate metabolism EC:6.2.1.17

Glycerol:NADP+ oxidoreductase Glycerolipid metabolism EC:1.1.1.72 EC:1.1.1.2

Propanoate:CoA ligase (AMP-forming) Propanoate metabolism EC:6.2.1.1 EC:6.2.1.17

5,6-Dihydrothymine:NAD+ oxidoreductase Pyrimidine metabolism EC:1.3.1.1

ATP:(R)-glycerate 3-phosphotransferase Glycine, serine and threonine metabolism EC:2.7.1.31

3-hydroxypropanoate:NAD+ oxidoreductase beta-Alanine metabolism / Propanoate metabolism EC:1.1.1.59

Pyruvate:[dihydrolipoyllysine-residue acetyltransferase]-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-acetylating) EC:1.2.4.1

2-oxoglutarate:[dihydrolipoyllysine-residue succinyltransferase]-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-succinylating) EC:1.2.4.2

3-methyl-2-oxobutanoate:[dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-2-methylpropanoylating) EC:1.2.4.4

4-methyl-2-oxopentanoate:[dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-2-methylpropanoylating) EC:1.2.4.4

D-Glyceraldehyde:NAD+ oxidoreductase Glycerolipid metabolism EC:1.2.1.3

Isocitrate:NADP+ oxidoreductase (decarboxylating) Citrate cycle (TCA cycle) EC:1.1.1.42

2-Oxoadipate:lipoamde 2-oxidoreductase(decarboxylating and acceptor-succinylating) Lysine degradation EC:1.2.4.2

N6-(L-1,3-Dicarboxypropyl)-L-lysine:NAD+ oxidoreductase; N6-(L-1,3-Dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-glutamate-forming) Lysine degradation EC:1.5.1.9

Phenylacetaldehyde:NAD+ oxidoreductase Phenylalanine metabolism / Styrene degradation EC:1.2.1.5 EC:1.2.1.39

Aldehyde:NADP+ oxidoreductase Phenylalanine metabolism EC:1.2.1.5

(S)-Methylmalonyl-CoA hydrolase Propanoate metabolism EC:3.1.2.17

ATP:pantothenate 4-phosphotransferase Pantothenate and CoA biosynthesis EC:2.7.1.33

3-hydroxyisobutyryl-Coenzyme A hydrolase (mitochondrial)

N-[(R)-4-Phosphopantothenoyl]-L-cysteine carboxy-lyase Pantothenate and CoA biosynthesis EC:4.1.1.36

(S)-Methylmalonate semialdehyde:NAD+ oxidoreductase Valine, leucine and isoleucine degradation EC:1.2.1.3

Trans-Tetradec-2-enoyl-CoA reductase Fatty acid elongation in mitochondria EC:1.3.1.38

(S)-3-Methyl-2-oxopentanoate:[dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-2-methylpropanoylating) EC:1.2.4.4

ATP:pantothenate 4-phosphotransferase Pantothenate and CoA biosynthesis EC:2.7.1.33

L-1-Pyrroline-3-hydroxy-5-carboxylate:NADP+ oxidoreductase Arginine and proline metabolism EC:1.5.1.12

(S)-3-Hydroxyhexadecanoyl-CoA:NAD+ oxidoreductase Fatty acid elongation in mitochondria / Fatty acid metabolism EC:1.1.1.211 EC:1.1.1.35

3,4-Dihydroxymandelaldehyde:NAD+ oxidoreductase Tyrosine metabolism EC:1.2.1.5

3,4-Dihydroxymandelaldehyde:NADP+ oxidoreductase Tyrosine metabolism EC:1.2.1.5

3-Methoxy-4-hydroxyphenylacetaldehyde:NAD+ oxidoreductase Tyrosine metabolism EC:1.2.1.5

3-Methoxy-4-hydroxyphenylacetaldehyde:NADP+ oxidoreductase Tyrosine metabolism EC:1.2.1.5

3-Methoxy-4-hydroxyphenylglycolaldehyde:NAD+ oxidoreductase Tyrosine metabolism EC:1.2.1.5

3-Methoxy-4-hydroxyphenylglycolaldehyde:NADP+ oxidoreductase Tyrosine metabolism EC:1.2.1.5

TCDB:2.A.1.13.5 TCDB:2.A.1.13.1

TCDB:2.A.1.13.5 TCDB:2.A.1.13.1

Transport reaction

Mitochondrial Carrier (MC) TCDB:2.A.29.7.2

Mitochondrial Carrier (MC) TCDB:2.A.29.7.2

Mitochondrial Carrier (MC) TCDB:2.A.29.7.2

Mitochondrial Carrier (MC) TCDB:2.A.29.7.2

Mitochondrial Carrier (MC) TCDB:2.A.29.7.2

Mitochondrial Carrier (MC) TCDB:2.A.29.7.2

Mitochondrial Carrier (MC) TCDB:2.A.29.7.2

Mitochondrial Carrier (MC) TCDB:2.A.29.7.2

Mitochondrial Carrier (MC) TCDB:2.A.29.7.2

Mitochondrial Carrier (MC) TCDB:2.A.29.7.2

Mitochondrial Carrier (MC) TCDB:2.A.29.7.2

Mitochondrial Carrier (MC) TCDB:2.A.29.19.1

Mitochondrial Carrier (MC) TCDB:2.A.29.19.1

Mitochondrial Carrier (MC) TCDB:2.A.29.19.1

Mitochondrial Carrier (MC) TCDB:2.A.29.19.1

Mitochondrial Carrier (MC) TCDB:2.A.29.19.1

Mitochondrial Carrier (MC) TCDB:2.A.29.19.1

Mitochondrial Carrier (MC) TCDB:2.A.29.19.1

Mitochondrial Carrier (MC) TCDB:2.A.29.19.1

Mitochondrial Carrier (MC) TCDB:2.A.29.19.1

Mitochondrial Carrier (MC) TCDB:2.A.29.19.1

Mitochondrial Carrier (MC) TCDB:2.A.29.19.1

Mitochondrial Carrier (MC) TCDB:2.A.29.19.1

Mitochondrial Carrier (MC) TCDB:2.A.29.19.1

Mitochondrial Carrier (MC) TCDB:2.A.29.19.1

Mitochondrial Carrier (MC) TCDB:2.A.29.19.1

Mitochondrial Carrier (MC) TCDB:2.A.29.19.1

Mitochondrial Carrier (MC) TCDB:2.A.29.19.1

Mitochondrial Carrier (MC) TCDB:2.A.29.19.1

Mitochondrial Carrier (MC) TCDB:2.A.29.19.1

Thymidine Kinase

Steroid Delta-Isomerase

3Alpha-Hydroxysteroid 3-Dehydrogenase (Si-Specific)

Palmitoyl Coenzyme A Hydrolase

Amino-Acid N-Acetyltransferase

Glycine N-Acyltransferase

Amino-Acid N-Acetyltransferase

Glycine N-Acyltransferase

Glycine N-Acyltransferase

Glycine N-Acyltransferase

Palmitoyl Coenzyme A Hydrolase

Carbonyl Reductase (NADPH)

Alcohol Dehydrogenase

Aldehyde Dehydrogenase (NAD+)

Carbonyl Reductase (NADPH)

Carbonyl Reductase (NADPH)

Carbonyl Reductase (NADPH)

Carbonyl Reductase (NADPH)

Saccharopine dehydrogenase (NADP, L-lysine forming), mitochondrial

Saccharopine dehydrogenase (NAD, L-glutamate forming), mitochondrial

L-sulfolactate dehydrogenase (NAD+), mitochondrial

Superoxide dismutase

Succinate-semialdehyde:NAD+ oxidoreductase, mitochondria

Thiamin pyrophosphatase, mitochondrial

NAD(P) transhydrogenase

Tetrahydrofolate aminomethyltransferase mitochondrial

Thiamine transport in via proton symport, mitochondrial

Thymidine kinase (ATP:thymidine)

Thioredoxin reductase NADPH

Vitamin D-25-hydroxylase (D2)

Vitamin D-25-hydroxylase (D3)

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Universal metabolite ?

h

External database links

InChI Key: GPRLSGONYQIRFK-UHFFFAOYSA-N
Reactome Compound: 1132304, 113529, 1470067, 156540, 163953, 193465, 194688, 2000349, 2872447, 351626, 372511, 374900, 425969, 425978, 425999, 427899, 428040, 428548, 5668577, 70106, 74722
SEED Compound: cpd00067
CHEBI: CHEBI:10744, CHEBI:13357, CHEBI:15378, CHEBI:5584
Human Metabolome Database: HMDB59597
MetaNetX (MNX) Chemical: MNXM1
KEGG Compound: C00080
BioCyc: META:PROTON

Provided by MetaNetX (CC BY 4.0)

Old identifiers

h[m]

h in other models