BiGG Models

Metabolite: h_e

Descriptive name:

H+

Model:

Formula:

H

Charge:

1

Compartment:

e - extracellular space

Reactions:

BiGG ID

Name

2 hydroxybutyrate cotransport with proton

4 aminobutyrate reversible transport in via proton symport

Acetoacetate transport via proton symport

Acetone transport via proton symport

Acetylcholinesterase

Acetate reversible transport via proton symport

Adenosine deaminase, extracellular

Transport of Alanylalanine by the apical PEPT1 amino acid transporters across the brush border cells of the enterocytes of the intestine and renal cells

L alanine reversible transport via proton symport

Alanine transport (Na, H coupled)

Transport of Alanine by y+LAT1 or y+LAT2 with co-transporter of h in small intestine and kidney

Asparagine transport (Na, H coupled)

D-aspartate transport via Na, H symport and K antiport

L-aspartate transport via Na, H symport and K antiport

ATP diphosphohydrolase

ATP diphosphohydrolase

Beta Alanine transport in via proton symport

(R)-3-Hydroxybutanoate transport via H+ symport

Butyrate transport via proton symport, reversible

Transport of L-Carnosine by the apical PEPT1 amino acid transporters across the brush border cells of the enterocytes of the intestine and renal cells

Cys-Gly transport in via proton symport

Hydrolysis of cholesterol ester by cholesterol esterase

Citrate reversible transport via symport

L-carnitine outward transport (H+ antiport)

Cysteamine:Oxygen Oxidoreductase, Extracellular

Transport of L-Cysteine into the cell coupled with co-transport with Sodium and counter transport with proton by SNAT5 transporter.

Deoxyadenosine deaminase, extracellular

D-alanine transport via proton symport

D lactate transport via proton symport

Pyrophasphatase (dephospho-CoA, extracellular)

FAD diphosphatase

Uptake of food iron by DMT1 transporter

Fe(III) reduction (ascorbate)

Folate transport via proton simport

D-galactose transport via proton symport

D-glucose transport in via proton symport

D-glucose transport in via proton symport

Glutamine transport (Na, H coupled)

Transport of Glutamine by y+LAT1 or y+LAT2 with co-transporter of h in small intestine and kidney

Glutamate transport via Na, H symport and K antiport

Transport of Glycylleucine by the apical PEPT1 amino acid transporters across the brush border cells of the enterocytes of the intestine and renal cells

Transport of Glycylphenylalanine by the apical PEPT1 amino acid transporters across the brush border cells of the enterocytes of the intestine and renal cells

Transport of Glycylproline by the apical PEPT1 amino acid transporters across the brush border cells of the enterocytes of the intestine and renal cells

Transport of Glycylsarcosine by the apical PEPT1 amino acid transporters across the brush border cells of the enterocytes of the intestine, renal cells and brain.

Transport of Glycine into the cell coupled with co-transport with Sodium and counter transport with proton by SNAT5 transporter.

Glycine reversible transport via proton symport

HCO3 equilibration reaction, extracellular

Histidine transport (Na, H coupled)

Transport of Histidine by y+LAT1 or y+LAT2 with co-transporter of h in small intestine and kidney

H+/K+ gastric/non-gastric P-ATPase and ABC ATPase

Inositol transport in via proton symport

Potassium transport out via proton antiport

Transport of Leucylglycine by the apical PEPT1 amino acid transporters across the brush border cells of the enterocytes of the intestine and renal cells

Transport of Leucylleucine by the apical PEPT1 amino acid transporters across the brush border cells of the enterocytes of the intestine and renal cells

Transport of Leucine by y+LAT1 or y+LAT2 with co-transporter of h in small intestine and kidney

L lactate reversible transport via proton symport

Lipase, extracellular

Lipase, extracellular

Transport of Methionine by y+LAT1 or y+LAT2 with co-transporter of h in small intestine and kidney

Transport of Nicotinate

NAD nucleosidase,extracellular

NADP nucleosidase,extracellular

Bicarbonate transport (HCl/NaHCO3 exchange)

Bicarbonate transport (HCl/NaHCO3 exchange) (2 HCO3)

Sodium proton antiporter HNA is 11

Nucleoside-diphosphatase (IDP), extracellular

Nucleoside-diphosphatase (GDP), extracellular

Nucleoside-diphosphatase (UDP), extracellular

Nucleoside-diphosphatase (UTP), extracellular

Ammonia transport via proton antiport

Nucleoside-triphosphatase (GTP)

Platelet-activating factor acetylhydrolase

Binding of pectins with deoxycholic acid in the intestinal lumen, reducing serum cholsterol levels.

Binding of pectins with glycocholate in the intestinal lumen, reducing serum cholsterol levels.

Binding of pectins with taurocholate in the intestinal lumen, reducing serum cholsterol levels.

Transport of Phenylalanine by y+LAT1 or y+LAT2 with co-transporter of h in small intestine and kidney

Phospholipase A2

D-proline reversible transport via proton symport

Transport of Prolylglycine by the apical PEPT1 amino acid transporters across the brush border cells of the enterocytes of the intestine and renal cells

L proline reversible transport via proton symport

Phosphopantetheine Adenylyltransferase, Extracellular

Pyruvate transport in via proton symport

Fe(II):oxygen oxidoreductase Porphyrin and chlorophyll metabolism EC:1.16.3.1

UDPglucose pyrophosphohydrolase Pyrimidine metabolism / Starch and sucrose metabolism EC:3.6.1.45

CDP diphosphohydrolase Pyrimidine metabolism EC:3.6.1.5

CTP diphosphohydrolase Pyrimidine metabolism EC:3.6.1.5

Uridine triphosphate pyrophosphohydrolase Pyrimidine metabolism EC:3.6.1.19

2-Deoxyguanosine 5-triphosphate pyrophosphohydrolase Purine metabolism EC:3.6.1.19

DTDP diphosphohydrolase Pyrimidine metabolism EC:3.6.1.5

DTTP nucleotidohydrolase Pyrimidine metabolism EC:3.6.1.39

(5-Glutamyl)-peptide:amino-acid 5-glutamyltransferase Cyanoamino acid metabolism EC:2.3.2.2

(5-Glutamyl)-peptide:amino-acid 5-glutamyltransferase Cyanoamino acid metabolism EC:2.3.2.2

2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl) dihydropteridine triphosphate phosphohydrolase (alkaline optimum) Folate biosynthesis EC:3.1.3.1

Uroporphyrinogen I carboxy-lyase Porphyrin and chlorophyll metabolism EC:4.1.1.37

Zinc (Zn2+)-Iron (Fe2+) Permease (ZIP), TCDB:2.A.55.2.3

2',3'-Cyclic-Nucleotide 3'-Phosphodiesterase

Beta-Glucuronidase

Beta-Glucuronidase

Retinyl ester hydrolase (9-cis), extracellular

Retinyl ester hydrolase (11-cis), extracellular

Retinyl ester hydrolase, extracellular

Ribose transport in via proton symporter

L serine reversible transport via proton symport

Serine transport (Na, H coupled)

Sphingomyelin phosphodiesterase

Superoxide dismutase, extracellular

Transport of taurine into the intestinal cells by PAT1

Thiamine transport in via proton antiport

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Universal metabolite ?

h

External database links

InChI Key: GPRLSGONYQIRFK-UHFFFAOYSA-N
Reactome Compound: 1132304, 113529, 1470067, 156540, 163953, 193465, 194688, 2000349, 2872447, 351626, 372511, 374900, 425969, 425978, 425999, 427899, 428040, 428548, 5668577, 70106, 74722
SEED Compound: cpd00067
CHEBI: CHEBI:10744, CHEBI:13357, CHEBI:15378, CHEBI:5584
Human Metabolome Database: HMDB59597
MetaNetX (MNX) Chemical: MNXM1
KEGG Compound: C00080
BioCyc: META:PROTON

Provided by MetaNetX (CC BY 4.0)

Old identifiers

h[e]

h in other models