Reaction: IBUP_SCYP3hep


Descriptive name:

Oxidation of S-ibuprofen to 3-hydroxy-ibuprofen in heaptocytes

Model:

Recon3D

Reaction:

h_r + nadph_r + o2_r + ibup__S_r → h2o_r + nadp_r + 3hibup__S_r

Metabolites:


Default bounds:

(0.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Drug metabolism

Gene Reaction Rule:

1559_AT1 or 1558_AT1 or 1576_AT1 or 1557_AT1

Genes:

1576_AT1 (CYP3A4)
1558_AT1 (CYP2C8)
1559_AT1 (CYP2C9)
1557_AT1 (CYP2C19)


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Universal reaction ?

External database links

Old identifiers

    IBUP_SCYP3hep

IBUP_SCYP3hep in other models