Oxidation of atorvastatin acid to 4-hydroxy-atorvastatin-acid in hepatocytes
h_r + nadph_r + o2_r + atvacid_r → h2o_r + nadp_r + 4hatvacid_r
(0.0, 1000.0)
0.0
Drug metabolism
1576_AT1 or 1577_AT1 or 1558_AT1
1576_AT1
(CYP3A4)
1558_AT1
(CYP2C8)
1577_AT1
(CYP3A5)