Reaction: TMDM1hr

Descriptive name:

Tolyl methylhydroxylation of torasemide in hepatocytes

Model:

Recon3D

Reaction:

h_r + nadph_r + o2_r + tmd_r → h2o_r + nadp_r + tmdm1_r

Metabolites:

Stoichiometry
BiGG ID
Name
1.0
h2o_r
H2O H2O
-1.0
h_r
H+
1.0
nadp_r
Nicotinamide adenine dinucleotide phosphate
-1.0
nadph_r
Nicotinamide adenine dinucleotide phosphate - reduced
-1.0
o2_r
O2 O2
-1.0
tmd_r
Torasemide
1.0
tmdm1_r
Torasemide-M1

Default bounds:

(0.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Drug metabolism

Gene Reaction Rule:

1559_AT1

Genes:

1559_AT1 (CYP2C9)

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Universal reaction ?

External database links

Old identifiers

    TMDM1hr

TMDM1hr in other models