Reaction: P4501B1r

Descriptive name:

Cytochrome P450 1B1

Model:

Recon3D

Reaction:

h_r + nadph_r + o2_r + estradiol_r → h2o_r + nadp_r + hestratriol_r

Metabolites:

Stoichiometry
BiGG ID
Name
1.0
h2o_r
H2O H2O
-1.0
h_r
H+
1.0
nadp_r
Nicotinamide adenine dinucleotide phosphate
-1.0
nadph_r
Nicotinamide adenine dinucleotide phosphate - reduced
-1.0
o2_r
O2 O2
-1.0
estradiol_r
Estradiol c
1.0
hestratriol_r
4,17 dihydroxy estradiol

Default bounds:

(0.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Steroid metabolism

Gene Reaction Rule:

1545_AT1 or 1576_AT1

Genes:

1576_AT1 (CYP3A4)
1545_AT1 (CYP1B1)

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Universal reaction ?

External database links

Provided by MetaNetX (CC BY 4.0)

Old identifiers

    P4501B1r

P4501B1r in other models