Demethylation of rosuvastatin in hepatocytes
h_r + nadph_r + o2_r + 2.0 ahcys_r + rsv_r → nadp_r + 2.0 amet_r + h2o2_r + ndersv_r
(0.0, 1000.0)
0.0
Drug metabolism
1559_AT1 or 1557_AT1
1557_AT1
(CYP2C19)
1559_AT1
(CYP2C9)