Reaction: NDERSVhc


Descriptive name:

Demethylation of rosuvastatin in hepatocytes

Model:

Recon3D

Reaction:

h_r + nadph_r + o2_r + 2.0 ahcys_r + rsv_r → nadp_r + 2.0 amet_r + h2o2_r + ndersv_r

Metabolites:


Default bounds:

(0.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Drug metabolism

Gene Reaction Rule:

1559_AT1 or 1557_AT1

Genes:

1557_AT1 (CYP2C19)
1559_AT1 (CYP2C9)


Report an error on this page ?

Universal reaction ?

External database links

Old identifiers

    NDERSVhc

NDERSVhc in other models