Universal reaction: NDERSVhc

Descriptive name:

Demethylation of rosuvastatin in hepatocytes

Reaction:

h_r + nadph_r + o2_r + 2.0 ahcys_r + rsv_r ⇌ nadp_r + 2.0 amet_r + h2o2_r + ndersv_r

Metabolites:

Stoichiometry
BiGG ID
Name
-1.0
h_r
H+
1.0
nadp_r
Nicotinamide adenine dinucleotide phosphate
-1.0
nadph_r
Nicotinamide adenine dinucleotide phosphate - reduced
-1.0
o2_r
O2 O2
-2.0
ahcys_r
S-Adenosyl-L-homocysteine
2.0
amet_r
S-Adenosyl-L-methionine
1.0
h2o2_r
Hydrogen peroxide
-1.0
rsv_r
Rosuvastatin
1.0
ndersv_r
N-desmethyl-rosuvastatin

NDERSVhc in BiGG models:

Organism
Model
Homo sapiens
Recon3D

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External database links

Old identifiers

    NDERSVhc