Reaction: DESFVShc

Descriptive name:

Oxidation of fluvastatin to N-desisopropyl-fluvastatin in hepatocytes

Model:

Recon3D

Reaction:

4.0 h_r + nadph_r + o2_r + 3.0 ahcys_r + fvs_r → nadp_r + 3.0 amet_r + h2o2_r + desfvs_r

Metabolites:

Stoichiometry
BiGG ID
Name
-4.0
h_r
H+
1.0
nadp_r
Nicotinamide adenine dinucleotide phosphate
-1.0
nadph_r
Nicotinamide adenine dinucleotide phosphate - reduced
-1.0
o2_r
O2 O2
-3.0
ahcys_r
S-Adenosyl-L-homocysteine
3.0
amet_r
S-Adenosyl-L-methionine
1.0
h2o2_r
Hydrogen peroxide
-1.0
fvs_r
Fluvastatin
1.0
desfvs_r
N-desisopropyl-fluvastatin

Default bounds:

(0.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Drug metabolism

Gene Reaction Rule:

1559_AT1

Genes:

1559_AT1 (CYP2C9)

Report an error on this page ?

Universal reaction ?

External database links

Old identifiers

    DESFVShc

DESFVShc in other models