Universal reaction: DESFVShc

Descriptive name:

Oxidation of fluvastatin to N-desisopropyl-fluvastatin in hepatocytes

Reaction:

4.0 h_r + nadph_r + o2_r + 3.0 ahcys_r + fvs_r ⇌ nadp_r + 3.0 amet_r + h2o2_r + desfvs_r

Metabolites:

Stoichiometry
BiGG ID
Name
-4.0
h_r
H+
1.0
nadp_r
Nicotinamide adenine dinucleotide phosphate
-1.0
nadph_r
Nicotinamide adenine dinucleotide phosphate - reduced
-1.0
o2_r
O2 O2
-3.0
ahcys_r
S-Adenosyl-L-homocysteine
3.0
amet_r
S-Adenosyl-L-methionine
1.0
h2o2_r
Hydrogen peroxide
-1.0
fvs_r
Fluvastatin
1.0
desfvs_r
N-desisopropyl-fluvastatin

DESFVShc in BiGG models:

Organism
Model
Homo sapiens
Recon3D

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External database links

Old identifiers

    DESFVShc