Reaction: ATVLACGLCURhc

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Descriptive name:

Glucuronidation of atorvastatin lactone to atorvastain lactone ether glucuronide (G3) in hepatocytes

Model:

Recon3D

Reaction:

udpglcur_r + atvlac_r → h_r + udp_r + atvlacgluc_r

Metabolites:

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Default bounds:

(0.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Drug metabolism

Gene Reaction Rule:

54659_AT1 or 54657_AT1 or 54658_AT1 or 54576_AT1 or 7364_AT1

Genes:

54576_AT1 (UGT1A8)
54657_AT1 (UGT1A4)
54658_AT1 (UGT1A1)
54659_AT1 (UGT1A3)
7364_AT1 (UGT2B7)

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