Gene: 54576_AT1

Descriptive name:

UGT1A8

Model:

Recon3D

Position:

Left: 233617708 – Right: 233772559

Strand:

Plus

Chromosome:

NC_000002.12

Associated reactions:

BiGG ID
Name
Gene reaction rule
UGT1A10r_1
UDP-Glucuronosyltransferase 1-10 Precursor, Microsomal
54576_AT1
UGT1A1r
UDP-glucuronosyltransferase 1-10 precursor, microsomal
54575_AT1 or 54576_AT1
UGT1A2r
UDP-glucuronosyltransferase 1-10 precursor, microsomal
54575_AT1 or 54576_AT1 or 54578_AT1 or 54579_AT1 or 54600_AT1 or 54658_AT1 or 54659_AT1 or 54577_AT1 or 54657_AT1
UGT1A3r
UDP-glucuronosyltransferase 1-10 precursor, microsomal
7364_AT1 or 54575_AT1 or 54490_AT1 or 54576_AT1 or 7367_AT1
UGT1A4r
UDP-glucuronosyltransferase 1-10 precursor, microsomal
54575_AT1 or 54490_AT1 or 54576_AT1
UGT1A5r
UDP-glucuronosyltransferase 1-10 precursor, microsomal
54575_AT1 or 54576_AT1
UGT1A5r2
UDP-glucuronosyltransferase 1-10 precursor, microsomal (13-cis)
54576_AT1 or 54575_AT1 or 54600_AT1 or 10720_AT1 or 7367_AT1 or 7363_AT1 or 54578_AT1 or 54657_AT1 or 54659_AT1 or 54579_AT1 or 7365_AT1 or 7366_AT1 or 54490_AT1 or 54577_AT1 or 54658_AT1
UGT1A6r
UDP-glucuronosyltransferase 1-10 precursor, microsomal
54575_AT1 or 54576_AT1
UGT1A7r
UDP-glucuronosyltransferase 1-10 precursor, microsomal
54575_AT1 or 54576_AT1
UGT1A8r
UDP-glucuronosyltransferase 1-10 precursor, microsomal
7363_AT1 or 54575_AT1 or 54490_AT1 or 54576_AT1
BIDGLCURr
Bilirubin Di-Glucuronide Production
54576_AT1
ATVACYLGLUChc
Glucuronidation of atorvastatin to atorvastatin acyl glucuronide (G2) in hepatocytes
54659_AT1 or 54657_AT1 or 54658_AT1 or 54576_AT1 or 7364_AT1
ATVLACGLCURhc
Glucuronidation of atorvastatin lactone to atorvastain lactone ether glucuronide (G3) in hepatocytes
54659_AT1 or 54657_AT1 or 54658_AT1 or 54576_AT1 or 7364_AT1
LSTNM7hr
Glucuronidation of losartan to losartan-M7/Losartan-N2-glucuronide in hepatocytes
54658_AT1 or 54659_AT1 or 54657_AT1 or 54577_AT1 or 54576_AT1 or 54600_AT1 or 54575_AT1 or 7364_AT1 or 7367_AT1

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External database links

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Old identifiers

    54576.1

Latest BiGG Models publication:

King ZA, Lu JS, Dräger A, Miller PC, Federowicz S, Lerman JA, Ebrahim A, Palsson BO, and Lewis NE. BiGG Models: A platform for integrating, standardizing, and sharing genome-scale models (2016) Nucleic Acids Research 44(D1):D515-D522. doi:10.1093/nar/gkv1049

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