Gene: 54658_AT1


Descriptive name:

UGT1A1

Model:

Recon3D

Position:

Left: 233760288 – Right: 233772559

Strand:

Plus

Chromosome:

NC_000002.12

Associated reactions:

BiGG ID
Name
Gene reaction rule
UGT1A2r
UDP-glucuronosyltransferase 1-10 precursor, microsomal
54575_AT1 or 54576_AT1 or 54578_AT1 or 54579_AT1 or 54600_AT1 or 54658_AT1 or 54659_AT1 or 54577_AT1 or 54657_AT1
UGT1A5r2
UDP-glucuronosyltransferase 1-10 precursor, microsomal (13-cis)
54576_AT1 or 54575_AT1 or 54600_AT1 or 10720_AT1 or 7367_AT1 or 7363_AT1 or 54578_AT1 or 54657_AT1 or 54659_AT1 or 54579_AT1 or 7365_AT1 or 7366_AT1 or 54490_AT1 or 54577_AT1 or 54658_AT1
RE2147C
Glucuronosyltransferase
54658_AT1
RE2404C
Glucuronosyltransferase
54658_AT1
RE2405C
Glucuronosyltransferase
54658_AT1
ACMPGLUChr
Glucuronidation of acetaminophen in hepatocytes
54600_AT1 or 54578_AT1 or 54658_AT1
ATVACYLGLUChc
Glucuronidation of atorvastatin to atorvastatin acyl glucuronide (G2) in hepatocytes
54659_AT1 or 54657_AT1 or 54658_AT1 or 54576_AT1 or 7364_AT1
ATVLACGLCURhc
Glucuronidation of atorvastatin lactone to atorvastain lactone ether glucuronide (G3) in hepatocytes
54659_AT1 or 54657_AT1 or 54658_AT1 or 54576_AT1 or 7364_AT1
CVM1GLUChc
Glucuronidation of cerivastatin-M1
54658_AT1 or 54659_AT1
CVM23GLUChc
Glucuronidation of cerivastatin-M23
54658_AT1 or 54659_AT1
GLC3MEACPhr
Glucuronidation of 3-methoxy-acetaminophen in hepatocytes
54600_AT1 or 54578_AT1 or 54658_AT1
LSTNM7hr
Glucuronidation of losartan to losartan-M7/Losartan-N2-glucuronide in hepatocytes
54658_AT1 or 54659_AT1 or 54657_AT1 or 54577_AT1 or 54576_AT1 or 54600_AT1 or 54575_AT1 or 7364_AT1 or 7367_AT1
PTVSTGLUChc
Glucuronidation of pitavastatin in hepatocytes
54658_AT1 or 54659_AT1 or 7364_AT1 or 54657_AT1 or 54578_AT1
SMVGLUChep
Glucuronidation of the open acid form of simvastatin
54658_AT1 or 54659_AT1

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External database links

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Old identifiers

    54658.1

Latest BiGG Models publication:

King ZA, Lu JS, Dräger A, Miller PC, Federowicz S, Lerman JA, Ebrahim A, Palsson BO, and Lewis NE. BiGG Models: A platform for integrating, standardizing, and sharing genome-scale models (2016) Nucleic Acids Research 44(D1):D515-D522. doi:10.1093/nar/gkv1049


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