Gene: 54659_AT1


Descriptive name:

UGT1A3

Model:

Recon3D

Position:

Left: 233729127 – Right: 233772559

Strand:

Plus

Chromosome:

NC_000002.12

Associated reactions:

BiGG ID
Name
Gene reaction rule
UGT1A2r
UDP-glucuronosyltransferase 1-10 precursor, microsomal
54575_AT1 or 54576_AT1 or 54578_AT1 or 54579_AT1 or 54600_AT1 or 54658_AT1 or 54659_AT1 or 54577_AT1 or 54657_AT1
UGT1A5r2
UDP-glucuronosyltransferase 1-10 precursor, microsomal (13-cis)
54576_AT1 or 54575_AT1 or 54600_AT1 or 10720_AT1 or 7367_AT1 or 7363_AT1 or 54578_AT1 or 54657_AT1 or 54659_AT1 or 54579_AT1 or 7365_AT1 or 7366_AT1 or 54490_AT1 or 54577_AT1 or 54658_AT1
CDCA24GSc
UDP-Glucuronosyltransferase (UGT) cytosolic (chenodeoxycholic acid)
54659_AT1 or 10941_AT1 or 79799_AT1
CDCA24GSr
UDP-Glucuronosyltransferase (UGT) (chenodeoxycholic acid)
54659_AT1 or 10941_AT1 or 79799_AT1
HDCA24GSc
UDP-Glucuronosyltransferase (UGT) cytosolic (hyodeoxycholic acid)
54659_AT1 or 10941_AT1 or 79799_AT1
HDCA24GSr
UDP-Glucuronosyltransferase (UGT) (hyodeoxycholic acid)
54659_AT1 or 10941_AT1 or 79799_AT1
LCA24GSc
UDP-Glucuronosyltransferase (UGT) cytosolic (lithocholic acid)
54659_AT1 or 7364_AT1 or 10941_AT1 or 79799_AT1
LCA24GSr
UDP-Glucuronosyltransferase (UGT) ER (lithocholic acid)
54659_AT1 or 7364_AT1 or 10941_AT1 or 79799_AT1
1HIBUP_SGLUhep
Glucuronidation of 1-hydroxy ibuprofen
54659_AT1 or 54600_AT1 or 7364_AT1
2HATVACIDGLUChr
Glucuronidation of 2-hydroxy-atorvastatin-acid in hepatocytes
54659_AT1 or 54657_AT1
2HATVLACGLUChr
Glucuronidation of 2-hydroxy-atorvastatin-lactone in hepatocytes
54659_AT1 or 54657_AT1
2HIBUP_SGLUhep
Glucuronidation of S-2-hydroxy ibuprofen
54659_AT1 or 54600_AT1 or 7364_AT1
3HIBUP_SGLUhep
Glucuronidation of S-3-hydroxy ibuprofen
54659_AT1 or 54600_AT1 or 7364_AT1
ATVACYLGLUChc
Glucuronidation of atorvastatin to atorvastatin acyl glucuronide (G2) in hepatocytes
54659_AT1 or 54657_AT1 or 54658_AT1 or 54576_AT1 or 7364_AT1
ATVETHGLUChc
Glucuronidation of atorvastatin to atorvastatin ether glucuronide (G1) in hepatocytes
54659_AT1 or 54657_AT1 or 54600_AT1
ATVLACGLCURhc
Glucuronidation of atorvastatin lactone to atorvastain lactone ether glucuronide (G3) in hepatocytes
54659_AT1 or 54657_AT1 or 54658_AT1 or 54576_AT1 or 7364_AT1
CARIBUP_SGLUhep
Glucuronidation of S-carboxy ibuprofen
54659_AT1 or 54600_AT1 or 7364_AT1
CVM1GLUChc
Glucuronidation of cerivastatin-M1
54658_AT1 or 54659_AT1
CVM23GLUChc
Glucuronidation of cerivastatin-M23
54658_AT1 or 54659_AT1
IBUPGT_HEP
Glucuronidation of ibuprofen in hepatocytes
54659_AT1 or 54600_AT1 or 7364_AT1
LSTNM7hr
Glucuronidation of losartan to losartan-M7/Losartan-N2-glucuronide in hepatocytes
54658_AT1 or 54659_AT1 or 54657_AT1 or 54577_AT1 or 54576_AT1 or 54600_AT1 or 54575_AT1 or 7364_AT1 or 7367_AT1
PTVSTGLUChc
Glucuronidation of pitavastatin in hepatocytes
54658_AT1 or 54659_AT1 or 7364_AT1 or 54657_AT1 or 54578_AT1
SMVGLUChep
Glucuronidation of the open acid form of simvastatin
54658_AT1 or 54659_AT1

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External database links

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Old identifiers

    54659.1

Latest BiGG Models publication:

King ZA, Lu JS, Dräger A, Miller PC, Federowicz S, Lerman JA, Ebrahim A, Palsson BO, and Lewis NE. BiGG Models: A platform for integrating, standardizing, and sharing genome-scale models (2016) Nucleic Acids Research 44(D1):D515-D522. doi:10.1093/nar/gkv1049


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