Reaction: ATVETHGLUChc

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Descriptive name:

Glucuronidation of atorvastatin to atorvastatin ether glucuronide (G1) in hepatocytes

Model:

Recon3D

Reaction:

2.0 udpglcur_r + atvacid_r → 2.0 h_r + 2.0 udp_r + atvethgluc_r

Metabolites:

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Default bounds:

(0.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Drug metabolism

Gene Reaction Rule:

54659_AT1 or 54657_AT1 or 54600_AT1

Genes:

54657_AT1 (UGT1A4)
54659_AT1 (UGT1A3)
54600_AT1 (UGT1A9)

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