Reaction: 56EPPVShc

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Descriptive name:

Oxidation of 3-alpha-iso-pravastatin to 5,6-epoxy-3-alpha-iso-pravastatin in hepatocytes

Model:

Recon3D

Reaction:

h_r + nadph_r + o2_r + 3ispvs_r → h2o_r + nadp_r + 56eppvs_r

Metabolites:

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Default bounds:

(0.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Drug metabolism

Gene Reaction Rule:

1576_AT1

Genes:

1576_AT1 (CYP3A4)

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