Reaction: 3OHACMPhr

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Descriptive name:

Oxidation of acetaminophen to 3-OH-acetaminophen in hepatocytes

Model:

Recon3D

Reaction:

h_r + nadph_r + o2_r + acmp_r → h2o_r + nadp_r + 3ohacmp_r

Metabolites:

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Default bounds:

(0.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Drug metabolism

Gene Reaction Rule:

1548_AT1 or 1571_AT1

Genes:

1548_AT1 (CYP2A6)
1571_AT1 (CYP2E1)

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