Reaction: TRIPVShc

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Descriptive name:

Formation of triol metabolite of pravastatin in hepatocytes

Model:

Recon3D

Reaction:

2.0 h_r + 2.0 nadph_r + 2.0 o2_r + pvs_r → 2.0 nadp_r + h2o2_r + tripvs_r

Metabolites:

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Default bounds:

(0.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Drug metabolism

Gene Reaction Rule:

1576_AT1

Genes:

1576_AT1 (CYP3A4)

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