Reaction: LNS14DMr

Descriptive name:

Cytochrome P450 lanosterol 14-alpha-demethylase

Model:

Recon3D

Reaction:

2.0 h_r + 3.0 nadph_r + 3.0 o2_r + lanost_r → 4.0 h2o_r + 3.0 nadp_r + 44mctr_r + for_r

Metabolites:

Stoichiometry
BiGG ID
Name
4.0
h2o_r
H2O H2O
-2.0
h_r
H+
3.0
nadp_r
Nicotinamide adenine dinucleotide phosphate
-3.0
nadph_r
Nicotinamide adenine dinucleotide phosphate - reduced
-3.0
o2_r
O2 O2
1.0
44mctr_r
4 4 dimethylcholesta 8 14 24 trienol C29H46O
1.0
for_r
Formate
-1.0
lanost_r
Lanosterol C30H50O

Default bounds:

(0.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Cholesterol metabolism

Gene Reaction Rule:

1595_AT1

Genes:

1595_AT1 (CYP51A1)

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Universal reaction ?

External database links

Provided by MetaNetX (CC BY 4.0)

Old identifiers

    r0781

LNS14DMr in other models