Reaction: I2FE2SS

Descriptive name:

ISC [2Fe-2S] Synthesis

Model:

iECDH10B_1368

Reaction:

fadh2_c + 2.0 fe2_c + 2.0 iscssh_c + iscu_c → fad_c + 6.0 h_c + 2.0 iscs_c + iscu_2fe2s_c

Metabolites:

Stoichiometry
BiGG ID
Name
1.0
fad_c
Flavin adenine dinucleotide oxidized
-1.0
fadh2_c
Flavin adenine dinucleotide reduced
-2.0
fe2_c
Fe2+ mitochondria
6.0
h_c
H+
2.0
iscs_c
IscS sulfur acceptor protein
-2.0
iscssh_c
IscS with bound sulfur
-1.0
iscu_c
IscU scaffold protein
1.0
iscu_2fe2s_c
IscU with bound [2Fe-2S] cluster

Default bounds:

(0.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Cofactor and Prosthetic Group Biosynthesis

Gene Reaction Rule:

ECDH10B_3998 and ECDH10B_2697 and ECDH10B_2696

Genes:

ECDH10B_2697 (iscS)
ECDH10B_2696 (iscU)
ECDH10B_3998 (cyaY)

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Universal reaction ?

External database links

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Old identifiers

    I2FE2SS

I2FE2SS in other models