Reaction: EPOXTAChr

Descriptive name:

Formation of epoxy derivative of tacrolimus in hepatocytes

Model:

Recon3D

Reaction:

3.0 h_r + o2_r + 3.0 ahcys_r + tacr_r → 3.0 amet_r + epoxtac_r

Metabolites:

Stoichiometry
BiGG ID
Name
-3.0
h_r
H+
-1.0
o2_r
O2 O2
-3.0
ahcys_r
S-Adenosyl-L-homocysteine
3.0
amet_r
S-Adenosyl-L-methionine
-1.0
tacr_r
Tacrolimus
1.0
epoxtac_r
31-O-Desmethyl,19-Hydroxy,37, 39-Epoxy-tacrolimus

Default bounds:

(0.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Drug metabolism

Gene Reaction Rule:

Genes:

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Universal reaction ?

External database links

Old identifiers

    EPOXTAChr

EPOXTAChr in other models