Reaction: 1331TACRhr

Descriptive name:

Demethylation of 31-O-desmethyl-tacrolimus to 13,31-O-Didesmethyl-tacrolimus in hepatocytes

Model:

Recon3D

Reaction:

h_r + ahcys_r + 31dmt_r → amet_r + 1331tacr_r

Metabolites:

Stoichiometry
BiGG ID
Name
-1.0
h_r
H+
-1.0
ahcys_r
S-Adenosyl-L-homocysteine
1.0
amet_r
S-Adenosyl-L-methionine
1.0
1331tacr_r
13,31-O-Didesmethyl-tacrolimus
-1.0
31dmt_r
31-DMT or M-II, 31-O-desmethyl tacrolimus

Default bounds:

(0.0, 1000.0)

Objective coefficient:

0.0

Subsystem:

Drug metabolism

Gene Reaction Rule:

Genes:

Report an error on this page ?

Universal reaction ?

External database links

Old identifiers

    1331TACRhr

1331TACRhr in other models